Effects of recovery sleep after one work week of mild sleep restriction on interleukin-6 and cortisol secretion and daytime sleepiness and performance

American Journal of Physiology - Endocrinology and Metabolism

Volumn 305, Issue 7, 2013, Pages

  Pejovic, Slobodanka ^a   Basta, Maria ^a,c   Vgontzas, Alexandros N ^a   Kritikou, Ilia ^a   Shaffer, Michele L ^a   Tsaoussoglou, Marina ^b   Stiffler, David ^a,d   Stefanakis, Zacharias ^c   Bixler, Edward O ^a   Chrousos, George P ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

^d New York School of Medicine   (United States)

Author keywords

Alertness; Cortisol; Il 6; Recovery sleep; Sleep restriction

Indexed keywords

HYDROCORTISONE; INTERLEUKIN 6;

ADULT; ALERTNESS; ARTICLE; BODY MASS; CYTOKINE RELEASE; DAYTIME SOMNOLENCE; FATIGUE; FEMALE; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; MALE; NIGHT SLEEP; NORMAL HUMAN; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SLEEP; SOMNOLENCE; TASK PERFORMANCE;

ALERTNESS; CORTISOL; IL-6; RECOVERY SLEEP; SLEEP RESTRICTION;

ADOLESCENT; ADULT; AROUSAL; ATTENTION; FATIGUE; FEMALE; HUMANS; HYDROCORTISONE; INTERLEUKIN-6; MALE; POLYSOMNOGRAPHY; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SLEEP; SLEEP DEPRIVATION; WAKEFULNESS;

EID: 84884915953     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00301.2013     Document Type: Article

References (44)

1. Akerstedt T, Kecklund G, Ingre M, Lekander M, Axelsson J. Sleep homeostasis during repeated sleep restriction and recovery: support from EEG dynamics. Sleep 32: 217-222, 2009.
2. Axelsson J, Kecklund G, Akerstedt T, Donofrio P, Lekander M, Ingre M. Sleepiness and performance in response to repeated sleep restriction and subsequent recovery during semi-laboratory conditions. Chronobiol Int 25: 297-308, 2008.
3. Balkin TJ, Rupp T, Picchioni D, Wesensten NJ. Sleep loss and sleepiness: current issues. Chest 134: 653-660, 2008.
4. Banks S, Van Dongen HP, Maislin G, Dinges DF. Neurobehavioral dynamics following chronic sleep restriction: dose-response effects of one night for recovery. Sleep 33: 1013-1026, 2010.
5. Belenky G, Wesensten NJ, Thorne DR, Thomas ML, Sing HC, Redmond DP, Russo MB, Balkin TJ. Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: a sleep dose-response study. J Sleep Res 12: 1-12, 2003.
6. Bixler EO, Papaliaga MN, Vgontzas AN, Lin HM, Pejovic S, Karataraki M, Vela-Bueno A, Chrousos GP. Women sleep objectively better than men and the sleep of young women is more resilient to external stressors: effects of age and menopause. J Sleep Res 18: 221-228, 2009.
7. Bixler EO, Vgontzas AN, Lin HM, Calhoun SL, Vela-Bueno A, Kales A. Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression. J Clin Endocrinol Metab 90: 4510-4515, 2005.
8. Bonnet MH, Arand DL. We are chronically sleep deprived. Sleep 18: 908-911, 1995.
9. Borbély AA, Achermann P. Sleep homeostasis and models of sleep regulation. J Biol Rhythms 14: 557-568, 1999.
10. Brunner DP, Dijk DJ, Borbély AA. Repeated partial sleep deprivation progressively changes in EEG during sleep and wakefulness. Sleep 16: 100-113, 1993.
11. Dinges DF, Pack F, Williams K, Gillen KA, Powell JW, Ott GE, Aptowicz C, Pack AI. Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4-5 hours per night. Sleep 20: 267-77, 1997.
12. Everson CA, Szabo A. Recurrent restriction of sleep and inadequate recuperation induce both adaptive changes and pathological outcomes. Am J Physiol Regul Integr Comp Physiol 297: R1430-R1440, 2009.
13. Everson CA, Szabo A. Repeated exposure to severely limited sleep results in distinctive and persistent physiological imbalances in rats. PLoS One 6: e22987, 2011.
14. Faraut B, Boudjeltia KZ, Dyzma M, Rousseau A, David E, Stenuit P, Franck T, Van Antwerpen P, Vanhaeverbeek M, Kerkhofs M. Benefits of napping and an extended duration of recovery sleep on alertness and immune cells after acute sleep restriction. Brain Behav Immun 25: 16-24, 2010.
15. Haack M, Sanchez E, Mullington JM. Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep 30: 1145-1152, 2007.
16. Haack M, Kraus T, Schuld A, Dalal M, Koethe D, Pollmächer T. Diurnal variations of interleukin-6 plasma levels are confounded by blood drawing procedures. Psychoneuroendocrinology 27: 921-931, 2002.
17. Hoddes E, Zarcone V, Smythe H, Phillips R, Dement WC. Quantification of sleepiness: a new approach. Psychophysiology 10: 431-436, 1973.
18. Horne J. Why We Sleep. New York: Oxford Univ. Press, 1988.
19. Irwin MR, Carrillo C, Olmstead R. Sleep loss activates cellular markers of inflammation: sex differences. Brain Behav Immun 24: 54-57, 2010.
20. Irwin MR, Wang M, Campomayor CO, Collado-Hidalgo A, Cole S. Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation. Arch Intern Med 166: 1756-1762, 2006.
21. Leproult R, Copinschi G, Buxton O, Van Cauter E. Sleep loss results in an elevation of cortisol levels the next evening. Sleep 20: 865-870, 1997.
22. Meier-Ewert HK, Ridker PM, Rifai N, Regan MM, Price NJ, Dinges DF, Mullington JM. Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol 43: 678-683, 2004.
23. National Sleep Foundation. Sleep in America. Poll, 2010.
24. Nedeltcheva AV, Kessler L, Imperial J, Penev PD. Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance. J Clin Endocrinol Metab 94: 3242-3250, 2009.
25. Omisade A, Buxton OM, Rusak B. Impact of acute sleep restriction on cortisol and leptin levels in young women. Physiol Behav 99: 651-656, 2010.
26. Rechtschaffen A, Kales A. Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. Los Angeles: UCLA Brain Information Services, 1968.
27. Redline S, Kirchner HL, Quan SF, Gottlieb DJ, Kapur V, Newman A. The effects of age, sex, ethnicity, and sleep-disordered breathing on sleep architecture. Arch Intern Med 164: 406-418, 2004.
28. Richardson GS, Carskadon MA, Flagg W, van den Hoed J, Dement WC, Mitler MM. Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects. Electroencephalogr Clin Neurophysiol 45: 621-627, 1978.
29. Ridker PM, Rifai N, Stampfer MJ, Hennekens CH. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 101: 1767-1772, 2000.
30. Rupp TL, Wesensten NJ, Bliese PD, Balkin TJ. Banking sleep: realization of benefits during subsequent sleep restriction and recovery. Sleep 32: 311-321, 2009.
31. Schmid SM, Hallschmid M, Jauch-Chara K, Wilms B, Lehnert H, Born J, Schultes B. Disturbed glucoregulatory response to food intake after moderate sleep restriction. Sleep 34: 371-377, 2011.
32. Spiegel K, Leproult R, L'hermite-Balériaux M, Copinschi G, Penev PD, Van Cauter E. Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. J Clin Endocrinol Metab 89: 5762-5771, 2004.
33. Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet 354: 1435-1439, 1999.
34. Van Dongen HP, Maislin G, Mullington JM, Dinges DF. The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep 26: 117-126, 2003.
35. Van Leeuwen WM, Lehto M, Karisola P, Lindholm H, Luukkonen R, Sallinen M, Härmä M, Porkka-Heiskanen T, Alenius H. Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP. PLoS One 4: e4589, 2009.
36. Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Collins B, Basta M, Pejovic S, Chrousos GP. Selective effects of CPAP on sleep apnoeaassociated manifestations. Eur J Clin Invest 38: 585-595, 2008.
37. Vgontzas AN, Pejovic S, Zoumakis E, Lin HM, Bixler EO, Basta M, Fang J, Sarrigiannidis A, Chrousos GP. Daytime napping after a night of sleep loss decreases sleepiness, improves performance, and causes beneficial changes in cortisol and interleukin-6 secretion. Am J Physiol Endocrinol Metab 292: E253-E261, 2007.
38. Vgontzas AN, Bixler EO, Lin HM, Prolo P, Trakada G, Chrousos GP. IL-6 and its circadian secretion in humans. Neuroimmunomodulation 12: 131-140, 2005.
39. Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Follett H, Kales A, Chrousos GP. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab 89: 2119-2126, 2004.
40. Vgontzas AN, Chrousos GP. Sleep, the hypothalamic-pituitary-adrenal axis, and cytokines: multiple interactions and disturbances in sleep disorders. Endocrinol Metab Clin North Am 31: 15-36, 2002.
41. Vgontzas AN, Papanicolaou DA, Bixler EO, Hopper K, Lotsikas A, Lin HM, Kales A, Chrousos GP. Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia. J Clin Endocrinol Metab 85: 1151-1158, 2000.
42. Vgontzas AN, Mastorakos G, Bixler EO, Kales A, Gold PW, Chrousos GP. Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications. Clin Endocrinol (Oxf) 51: 205-215, 1999.
43. Ware JC, Risser MR, Manser T, Karlson KH Jr. Medical resident driving simulator performance following a night on call. Behav Sleep 4: 1-12, 2006.
44. Wu H, Zhao Z, Stone WS, Huang L, Zhuang J, He B, Zhang P, Li Y. Effects of sleep restriction periods on serum cortisol levels in healthy men. Brain Res Bull 77: 241-245, 2008.