A Penicillium sp. F33 metabolite and its synthetic derivatives inhibit acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in platelet-activating factor biosynthesis) and carrageenan-induced paw edema in mice

Biochemical Pharmacology

Volumn 86, Issue 5, 2013, Pages 632-644

  Yamazaki, Yasuhiro ^a   Yasuda, Kengo ^a   Matsuyama, Tensei ^a   Ishihara, Takuya ^a   Higa, Ryoko ^a   Sawairi, Taira ^a   Yamaguchi, Masahiko ^a   Egi, Masahiro ^a   Akai, Shuji ^a   Miyase, Toshio ^a   Ikari, Akira ^a   Miwa, Masao ^a   Sugatani, Junko ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Carrageenan induced edema; Fumigatin; Lyso PAF acetyltransferase; PAF biosynthesis; Platelet activating factor

Indexed keywords

ACETYL COENZYME A; ACYLTRANSFERASE; CARRAGEENAN; FUMIGATIN; LIPOPOLYSACCHARIDE; SATURATED FATTY ACID; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; GENE EXPRESSION; MACROPHAGE; MALE; METABOLITE; MOUSE; NONHUMAN; PAW EDEMA; PENICILLIUM; PRIORITY JOURNAL; RAT;

EID: 84884910253     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.06.021     Document Type: Article

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