Is time the missing component in protective ventilation strategies?

Critical Care Medicine

Volumn 41, Issue 10, 2013, Pages 2461-2462

  Nieman, Gary ^a   Gatto, Louis A ^b   Marx, William ^c   Habashi, Nader ^d  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c SYRACUSE VA MEDICAL CENTER   (United States)

^d R ADAMS COWLEY SHOCK TRAUMA CENTER   (United States)

Author keywords

mechanical ventilation; recruitment maneuver; tidal volume; ventilator induced lung injury; whole breath analysis

Indexed keywords

ENDOTOXIN; SURFACTANT PROTEIN B;

ADULT RESPIRATORY DISTRESS SYNDROME; AIRWAY PRESSURE; ARTIFICIAL VENTILATION; BREATH ANALYSIS; BREATHING MECHANICS; CELL DAMAGE; COMPLIANCE (PHYSICAL); EDITORIAL; ENDOTHELIUM INJURY; FLOW RATE; FUNCTIONAL RESIDUAL CAPACITY; LUNG INJURY; LUNG VOLUME; MICROCIRCULATION; NONHUMAN; PATHOPHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL;

ACUTE LUNG INJURY; ANIMALS; CONTINUOUS POSITIVE AIRWAY PRESSURE; ENDOTHELIAL CELLS; EPITHELIAL CELLS; LUNG COMPLIANCE; MALE;

EID: 84884828636     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31828ce91b     Document Type: Editorial

References (8)

1. Webb HH, Tierney DF: Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am Rev Respir Dis 1974; 110:556-565
2. De Prost N, Dreyfuss D: How to prevent ventilator-induced lung injury? Minerva Anestesiol 2012; 78:1054-1066
3. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-1308
4. Villar J, Blanco J, Añón JM, et al; ALIEN Network: The ALIEN study: Incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intensive Care Med 2011; 37:1932-1941
5. Silva PL, Moraes L, Santos RS, et al: Impact of pressure profile and duration of recruitment maneuvers on morphofunctional and biochemical variables in experimental lung injury. Crit Care Med 2011; 39:1074-1081
6. Ferguson ND, Cook, DJ, Guyatt GH, et al; the Oscillate Trial Investigators: the Canadian Critical Care Trials, Group. High- Frequency Oscillation in Early Acute Respiratory Distress Syndrome. N Engl J Med 2013; [Epub ahead of print]
7. Silva PL, Moraes L, Santos RS, et al: Recruitment Maneuvers Modulate Epithelial and Endothelial Cell Response According to Acute Lung Injury Etiology. Crit Care Med 2013; 41:e256-e265
8. Roy S, et al: Early airway pressure release ventilation prevents ARDS-A novel preventive approach to lung injury. Shock 2013; 39:28-38