Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1

Developmental Biology

Volumn 382, Issue 2, 2013, Pages 567-575

  Barembaum, Meyer ^a   Bronner, Marianne E ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Enhancer; Ets 1; Neural crest; Pax7; Sox9; TFAP2

Indexed keywords

CIS ACTING ELEMENT; HOMEODOMAIN PROTEIN; MYC PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR FOXD3; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR PAX7; TRANSCRIPTION FACTOR SOX; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; BIRD; CHICKEN; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; GENE MUTATION; GENE REGULATORY NETWORK; GENETIC CONSERVATION; LOSS OF FUNCTION MUTATION; MAMMAL; NEURAL CREST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPORTER GENE;

AVES; MAMMALIA;

EID: 84884815740     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2013.08.009     Document Type: Article

References (27)

1. Betancur P., Bronner-Fraser M., Sauka-Spengler T. Assembling neural crest regulatory circuits into a gene regulatory network. Annu. Rev. Cell Dev. Biol. 2010, 26:581-603.
2. Betancur P., Bronner-Fraser M., Sauka-Spengler T. Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. Proc. Natl. Acad. Sci. U S A. 2010, 107:3570-3575.
3. Boardman P.E., Sanz-Ezquerro J., Overton I.M., Burt D.W., Bosch E., Fong W.T., Tickle C., Brown W.R.A., Wilson S.A., Hubbard S.J. A comprehensive collection of chicken cDNAs. Curr. Biol. 2002, 12:1965-1969.
4. Bryne J.C., Valen E., Tang M.H., Marstrand T., Winther O., da Piedade I., Krogh A., Lenhard B., Sandelin A. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Res. 2008, 36:D102-D106.
5. Chen J.H., Wright C.D. PEA3, Oct 1 and Oct 2 positively regulate the human ETS1 promoter. Oncogene 1993, 8:3375-3383.
6. Cheung M., Briscoe J. Neural crest development is regulated by the transcription factor Sox9. Development 2003, 130:5681-5693.
7. Dittmer J. The biology of the Ets-1 proto-oncogene. Mol. Cancer 2003, 2:229.
8. Gao Z., Kim G.H., Mackinnon A.C., Flagg A.E., Bassett B., Earley J.U., Svensson E.C. Ets1 is required for proper migration and differentiation of the cardiac neural crest. Development 2010, 137:1543-1551.
9. Hamburger H., Hamilton H.L. A series of normal stages in thedevelopment of the chick embryo. J. Morphol. 1953, 88:49-92.
10. Jorcyk C.L., Watson D.K., Mavrothalassitis G.J., Papas T.S. The human ETS1 gene: genomic structure, promoter characterization and alternative splicing. Oncogene 1991, 6:523-532.
11. Jorcyk C.L., Garrett L.J., Maroulakou I.G., Watson D.K., Green J.E. Multiple regulatory regions control the expression of Ets-1 in the developing mouse: vascular expression conferred by intron I. Cell Mol. Biol. 1997, 43:211-225.
12. Kent W.J., Sugnet C.W., Furey T.S., Roskin K.M., Pringle T.H., Zahler A.M., Haussler D. The human genome browser at UCSC. Genome Res. 2002, 12:996-1006.
13. Meulemans D., Bronner-Fraser M. Gene-regulatory interactions in neural crest evolution and development. Dev. Cell 2004, 7:291-299.
14. Mori-Akiyama Y., Akiyama H., Rowitch D.H., de Crombrugghe B. Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. Proc. Natl. Acad. Sci. U S A. 2003, 100:9360-9365.
15. Oka T., Rairkar A., Chen J.H. Structural and functional analysis of the regulatory sequences of the ets-1 gene. Oncogene 1991, 6:2077-2083.
16. Sauka-Spengler T., Barembaum M. Gain- and loss-of-function approaches in the chick embryo. Methods Cell Biol. 2008, 87:237-256.
17. Sauka-Spengler T., Bronner-Fraser M. A gene regulatory network orchestrates neural crest formation. Nat. Rev. Mol. Cell Biol. 2008, 9:557-568.
18. Simões-Costa M.S., McKeown S.J., Tan-Cabugao J., Sauka-Spengler T., Bronner M.E. Dynamic and differential regulation of stem cell factor FoxD3 in the neural crest is encrypted in the genome. PLoS Genet. 2012, 8:e1003142.
19. Stuhlmiller T.J., Garcia-Castro M.I. Current perspectives of the signaling pathways directing neural crest induction. Cell. Mol. Life Sci. 2012, 69:3715-3737.
20. Szewczyk E., Nayak T., Oakley C.E., Edgerton H., Xiong Y., Taheri-Talesh N., Osmani S.A., Oakley B.R. Fusion PCR and gene targeting in Aspergillus nidulans. Nat. Protoc. 2006, 1:3111-3120.
21. Tahtakran S.A., Selleck M.A. Ets-1 expression is associated with cranial neural crest migration and vasculogenesis in the chick embryo. Gene Expr. Patterns 2003, 3:455-458.
22. Théveneau E., Duband J.L., Altabef M. Ets-1 confers cranial features on neural crest delamination. PLoS One 2007, 2:e1142.
23. Uchikawa M., Ishida Y., Takemoto T., Kamachi Y., Kondoh H. Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals. Dev. Cell 2003, 4:509-519.
24. Wahlbuhl M., Reiprich S., Vogl M.R., Bösl M.R., Wegner M. Transcription factor Sox10 orchestrates activity of a neural crest-specific enhancer in the vicinity of its gene. Nucleic Acids Res. 2012, 40:88-101.
25. Werner T., Hammer A., Wahlbuhl M., Bösl M.R., Wegner M. Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis. Nucleic Acids Res. 2007, 35:6526-6538.
26. Wilkinson D.G. Wholemount in situ hybridization of vertebrate embryos. In Situ Hybridization: A Practical Approach 1992, 75-83. IRL Press, Oxford. D.G. Wilkinson (Ed.).
27. Ye M., Coldren C., Liang X., Mattina T., Goldmuntz E., Benson D.W., Ivy D., Perryman M.B., Garrett-Sinha L.A., Grossfeld P. Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice. Hum. Mol. Genet 2010, 19:648-656.