Comparison of mycophenolic acid concentrations determined by a new PETINIA assay on the Dimension EXL analyzer and a HPLC-UV method

Clinical Biochemistry

Volumn 46, Issue 7-8, 2013, Pages 685-687

  Dasgupta, Amitava ^a   Tso, Gertie ^a   Chow, Loretta ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

CEDIA; HPLC UV; Mycophenolic acid; Positive bias

Indexed keywords

MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID; IMMUNOSUPPRESSIVE AGENT;

ACCURACY; ARTICLE; CALIBRATOR; CONTROLLED STUDY; CROSS REACTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; GRAFT RECIPIENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOASSAY; IMMUNOASSAY ANALYZER; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; PARTICLE ENHANCED TURBIDIMETRIC INHIBITION IMMUNOASSAY; PRIORITY JOURNAL; ULTRAVIOLET RADIATION; BLOOD; METHODOLOGY; ORGAN TRANSPLANTATION; PHOTOMETRY; PHYSIOLOGY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG MONITORING; HUMANS; IMMUNOASSAY; IMMUNOSUPPRESSIVE AGENTS; MYCOPHENOLIC ACID; NEPHELOMETRY AND TURBIDIMETRY; ORGAN TRANSPLANTATION; ULTRAVIOLET RAYS;

EID: 84884762296     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2012.11.025     Document Type: Article

References (10)

1. Wu J.C. Mycophenolate mofetil: molecular mechanisms of action. Perspex Drug Discov Design 1994, 2:185-204.
2. Bullingham R.E., Nicholls A.J., Kamm B.R. Clinical pharmacokinetics of mycophenolate mofetil. Clin Pharmacokinet 1998, 34:429-455.
3. Korecka M., Nikolic D., van Breemen R.B., Shaw L.M. Inhibition of inosine monophosphate dehydrogenase by mycophenolic acid glucuronide is attributable to the presence of trace quantities of mycophenolic acid. Clin Chem 1999, 45:1047-1050.
4. Tredger J.M., Brown N.W., Adams J., Gonde C.E., Dhawan A., Rela M., et al. Monitoring mycophenolate in liver transplant recipients: toward a therapeutic range. Liver Transpl 2004, 10:492-502.
5. Patel C.G., Akhlaghi F. High performance liquid chromatography method for the determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human plasma. Ther Drug Monit 2006, 28:116-122.
6. Tsina I., Kaloostian M., Lee R., Tarnowsaki T., Wong B. High performance liquid chromatographic method for the determination of mycophenolate mofetil in human plasma. J Chromatogr B Biomed Appl 1996, 681:347-353.
7. Elbarbry F.A., Shoker A. Simple high performance liquid chromatographic assay for mycophenolic acid in renal transplant patients. J Pharm Biomed Anal 2007, 43:788-792.
8. Shipkova M., Schutz E., Besenthal I., Fraunberger P., Weiland E. Investigation of the crossreactivity of mycophenolic acid glucuronide metabolites and of mycophenolic acid mofetil in the Cedia MPA assay. Ther Drug Monit 2010, 32:79-85.
9. Westley I.S., Ray J.E., Morris R.G. CEDIA mycophenolic acid assay compared with HPLC-UV in specimens from transplant recipients. Ther Drug Monit 2006, 28:632-636.
10. Irtan S., Azougagh S., Monchaud C., Popon M., Baudouin V., Jacqz-Aigrain E. Comparison of high performance liquid chromatography and enzyme multiplied immunoassay technique to monitor mycophenolic acid in pediatric renal recipients. Pediatr Nephrol 2008, 23:1859-1865.