High Coxiella burnetii DNA load in serum during acute Q fever is associated with progression to a serologic profile indicative of chronic Q fever

Journal of Clinical Microbiology

Volumn 51, Issue 10, 2013, Pages 3192-3198

  Wielders, C C H ^a,b   Wijnbergen, P C A ^a   Renders, N H M ^a   Schellekens, J J A ^a   Schneeberger, P M ^a   Wever, P C ^a   Hermans, M H A ^a  

^a JEROEN BOSCH HOSPITAL   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; ANTIBODY TITER; ARTICLE; BACTERIAL LOAD; BLOOD ANALYSIS; CONTROLLED STUDY; COXIELLA BURNETII; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE COURSE; ELISA KIT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; IMMUNOFLUORESCENCE TEST; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; PATIENT MONITORING; PREDICTIVE VALUE; PRIORITY JOURNAL; Q FEVER; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

ADULT; BACTERIAL LOAD; CHRONIC DISEASE; COXIELLA BURNETII; DNA, BACTERIAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; Q FEVER; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SERUM;

EID: 84884754180     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00993-13     Document Type: Article

References (29)

1. Maurin M, Raoult D. 1999. Q fever. Clin. Microbiol. Rev. 12:518-553. (Pubitemid 29484745)
2. van der Hoek W, Schneeberger PM, Oomen T, Wegdam-Blans MC, Dijkstra F, Notermans DW, Bijlmer HA, Groeneveld K, Wijkmans CJ, Rietveld A, Kampschreur LM, van Duynhoven Y. 2012. Shifting priorities in the aftermath of a Q fever epidemic in 2007 to 2009 in the Netherlands: from acute to chronic infection. Euro Surveill. 17:pii-20059. http://www.eurosurveillance.org/ViewArticle.aspx? ArticleId=20059.
3. Dijkstra F, van der Hoek W, Wijers N, Schimmer B, Rietveld A, Wijkmans CJ, Vellema P, Schneeberger PM. 2012. The 2007-2010 Q fever epidemic in The Netherlands: characteristics of notified acute Q fever patients and the association with dairy goat farming. FEMS Immunol. Med. Microbiol. 64:3-12.
4. Karagiannis I, Schimmer B, Van Lier A, Timen A, Schneeberger P, Van Rotterdam B, De Bruin A, Wijkmans C, Rietveld A, Van Duynhoven Y. 2009. Investigation of a Q fever outbreak in a rural area of The Netherlands. Epidemiol. Infect. 137:1283-1294.
5. Schimmer B, ter Schegget R, Wegdam M, Zuchner L, de Bruin A, Schneeberger PM, Veenstra T, Vellema P, van der Hoek W. 2010. The use of a geographic information system to identify a dairy goat farm as the most likely source of an urban Q-fever outbreak. BMC Infect. Dis. 10:69. doi:10.1186/1471-2334-10-69.
6. Veenstra T, Snijders BE, Schimmer B, Rietveld A, Van Dam S, Schneeberger PM, Dijkstra F, Van Der Sande MA, Van Der Hoek W. 2011. Risk factors for Q fever in the Netherlands. Webmed Central Infect. Dis. 2:WMC002006.
7. Dupont HT, Thirion X, Raoult D. 1994. Q fever serology: cutoff determination for microimmunofluorescence. Clin. Diagn. Lab. Immunol. 1:189-196. (Pubitemid 2057614)
8. Dupuis G, Péter O, Peacock M, Burgdorfer W, Haller E. 1985. Immunoglobulin responses in acute Q fever. J. Clin. Microbiol. 22:484-487. (Pubitemid 15239256)
9. Fournier PE, Marrie TJ, Raoult D. 1998. Diagnosis of Q fever. J. Clin. Microbiol. 36:1823-1834. (Pubitemid 28277760)
10. Raoult D, Marrie T, Mege J. 2005. Natural history and pathophysiology of Q fever. Lancet Infect. Dis. 5:219-226. (Pubitemid 40410067)
11. Wegdam-Blans MCA, Wielders CCH, Meekelenkamp J, Korbeeck JM, Herremans T, Tjhie HT, Bijlmer HA, Koopmans MPG, Schneeberger PM. 2012. Evaluation of commonly used serological tests for detection of Coxiella burnetii antibodies in well-defined acute and follow-up sera. Clin. Vaccine Immunol. 19:1110-1115.
12. Schneeberger PM, Hermans MHA, van Hannen EJ, Schellekens JJA, Leenders ACAP, Wever PC. 2010. Real-time PCR with serum samples is indispensable for early diagnosis of acute Qfever. Clin. Vaccine Immunol. 17:286-290.
13. Canadian Diseases Weekly Report. 1977. Comment on Q fever transmitted by blood transfusion-United States. Can. Dis. Wkly. Rep. 3:210. (Editorial.)
14. Fournier PE, Raoult D. 2003. Comparison of PCR and serology assays for early diagnosis of acute Q fever. J. Clin. Microbiol. 41:5094-5098. (Pubitemid 37429921)
15. Turra M, Chang G, Whybrow D, Higgins G, Qiao M. 2006. Diagnosis of acute Q fever by PCR on sera during a recent outbreak in rural South Australia. Ann. N. Y. Acad. Sci. 1078:566-569. (Pubitemid 44968680)
16. Parker NR, Barralet JH, Bell AM. 2006. Q fever. Lancet 367:679-688. (Pubitemid 43289158)
17. European Centre for Disease Prevention and Control. 2010. Risk assessment on Q fever. European Centre for Disease Prevention and Control, Stockholm, Sweden.
18. Wegdam-Blans MCA, Kampschreur LM, Delsing CE, Bleeker-Rovers CP, Sprong T, van Kasteren MEE, Notermans DW, Renders NHM, Bijlmer HA, Lestrade PJ, Koopmans MPG, Nabuurs-Franssen MH, Oosterheert JJ, Dutch Q Fever Consensus Group. 2012. Chronic Q fever: review of the literature and a proposal of new diagnostic criteria. J. Infect. 64:247-259.
19. Million M, Thuny F, Richet H, Raoult D. 2010. Long-term outcome of Qfever endocarditis: a 26-year personal survey. Lancet Infect. Dis. 10:527-535.
20. Schimmer B, Morroy G, Dijkstra F, Schneeberger PM, Weers-Pothoff G, Timen A, Wijkmans C, van der Hoek W. 2008. Large ongoing Q fever outbreak in the south of The Netherlands, 2008. Euro Surveill. 13: pii-18939. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId-18939.
21. Gikas A, Kofteridis DP, Manios A, Pediaditis J, Tselentis Y. 2001. Newer macrolides as empiric treatment for acute Q fever infection. Antimicrob. Agents Chemother. 45:3644-3646. (Pubitemid 33107898)
22. Marrie TJ. 2003. Coxiella burnetii pneumonia. Eur. Respir. J. 21:713-719. (Pubitemid 36432530)
23. van der Hoek W, Dijkstra F, Schimmer B, Schneeberger PM, Vellema P, Wijkmans C, ter Schegget R, Hackert V, van Duynhoven Y. 2010. Q fever in the Netherlands: an update on the epidemiology and control measures. Euro Surveill. 15:pii-19520. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19520.
24. van der Hoek W, Dijkstra F, Wijers N, Rietveld A, Wijkmans CJ, van Steenbergen JE, Notermans DW, Schneeberger PM. 2010. Three years of Q fever in the Netherlands: faster diagnosis. Ned. Tijdschr. Geneeskd. 154:A1845. (In Dutch.)
25. Jager MM, Weers-Pothoff G, Hermans MHA, Meekelenkamp JCE, Schellekens JJA, Renders NHM, Leenders ACAP, Schneeberger PM, Wever PC. 2011. Evaluation of a diagnostic algorithm for acute Q fever in an outbreak setting. Clin. Vaccine Immunol. 18:963-968.
26. Tilburg JJ, Melchers WJ, Pettersson AM, Rossen JWA, Hermans MHA, van Hannen EJ, Nabuurs-Franssen MH, de Vries MC, Horrevorts AM, Klaassen CHW. 2010. Interlaboratory evaluation of different extraction and real-time PCR methods for detection of Coxiella burnetii DNA in serum. J. Clin. Microbiol. 48:3923-3927.
27. van der Hoek W, Versteeg B, Meekelenkamp JCE, Renders NHM, Leenders ACAP, Weers-Pothoff I, Hermans MHA, Zaaijer HL, Wever PC, Schneeberger PM. 2011. Follow-up of 686 patients with acute Q fever and detection of chronic infection. Clin. Infect. Dis. 52:1431-1436.
28. Schuurman T, de Boer R, Patty R, Kooistra-Smid M, van Zwet A. 2007. Comparative evaluation of in-house manual, and commercial semiautomated and automated DNA extraction platforms in the sample preparation of human stool specimens for a Salmonella enterica 5=-nuclease assay. J. Microbiol. Methods 71:238-245. (Pubitemid 350151516)
29. Hogema BM, Slot E, Molier M, Schneeberger PM, Hermans MH, van Hannen EJ, van der Hoek W, Cuijpers HT, Zaaijer HL. 2012. Coxiella burnetii infection among blood donors during the 2009 Q-fever outbreak in The Netherlands. Transfusion 52:144-150.