Resting perfusion MPI-SPECT combined with cardiac 123I-mIBG sympathetic innervation imaging improves prediction of arrhythmic events in non-ischemic cardiomyopathy patients: Sub-study from the ADMIRE-HF trial

Journal of Nuclear Cardiology

Volumn 20, Issue 5, 2013, Pages 813-820

  Sood, Nitesh ^a   Al Badarin, Firas ^b   Parker, Matthew ^c,d   Pullatt, Raja ^c   Jacobson, Arnold F ^e   Bateman, Timothy M ^b   Heller, Gary V ^d  

^a Development for Southcoast Health System   (United States)

^b SAINT LUKE S MID AMERICA HEART INSTITUTE   (United States)

^c HARTFORD HOSPITAL   (United States)

^d UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^e GE HEALTHCARE   (United States)

Author keywords

delayed H M ratio; ICD risk stratification; ICD therapy; scar; Summed rest score

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123;

ADULT; AGED; ARTICLE; CARDIAC IMAGING; CLINICAL TRIAL (TOPIC); DISEASE SEVERITY; FEMALE; FOLLOW UP; HEART LEFT VENTRICLE EJECTION FRACTION; HEART VENTRICLE ARRHYTHMIA; HIGH RISK POPULATION; HUMAN; ISCHEMIC CARDIOMYOPATHY; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; MYOCARDIAL PERFUSION IMAGING; NONISCHEMIC CARDIOMYOPATHY; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RISK ASSESSMENT; SCAR; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYMPATHETIC INNERVATION;

3-IODOBENZYLGUANIDINE; ADULT; AGED; ANALYSIS OF VARIANCE; ARRHYTHMIAS, CARDIAC; CARDIOMYOPATHIES; CLINICAL TRIALS AS TOPIC; COHORT STUDIES; FEMALE; HEART; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL PERFUSION IMAGING; MYOCARDIUM; PERFUSION; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RISK; SYMPATHETIC NERVOUS SYSTEM; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84884700754     PISSN: 10713581     EISSN: 15326551     Source Type: Journal    
DOI: 10.1007/s12350-013-9750-y     Document Type: Article

References (23)

1. Stevenson WG, Stevenson LW, Middlekauff HR, Saxon LA. Sudden death prevention in patients with advanced ventricular dysfunction. Circulation 1993;88:2953-61.
2. Bardy GH, Lee KL, Mark DB, et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 2005;352:225-37.
3. Kadish A, Dyer A, Daubert JP, et al. Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy. N Engl J Med 2004;350:2151-8.
4. Epstein AE, DiMarco JP, Ellenbogen KA, et al. ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol 2008;51:e1-62.
5. Poole JE, Johnson GW, Hellkamp AS, et al. Prognostic importance of defibrillator shocks in patients with heart failure. N Engl J Med 2008;359:1009-17.
6. Daubert JP, Zareba W, Cannom DS, et al. Inappropriate implantable cardioverter-defibrillator shocks in MADIT II: Frequency, mechanisms, predictors, and survival impact. J Am Coll Cardiol 2008;51:1357-65.
7. Carroll DL, Hamilton GA. Quality of life in implanted cardioverter defibrillator recipients: The impact of a device shock. Heart Lung 2005;34:169-78.
8. Buxton AE, Lee KL, Hafley GE, et al. Limitations of ejection fraction for prediction of sudden death risk in patients with coronary artery disease: Lessons from the MUSTT study. J Am Coll Cardiol 2007;50:1150-7.
9. Jacobson AF, Senior R, Cerqueira MD, et al. Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView myocardial imaging for risk evaluation in heart failure) study. J Am Coll Cardiol 2010;55:2212-21.
10. Iles L, Pfluger H, Lefkovits L, et al. Myocardial fibrosis predicts appropriate device therapy in patients with implantable cardioverter- defibrillators for primary prevention of sudden cardiac death. J Am Coll Cardiol 2011;57:821-8.
11. van der Burg AE, Bax JJ, Boersma E, Pauwels EK, van der Wall EE, Schalij MJ. Impact of viability, ischemia, scar tissue, and revascularization on outcome after aborted sudden death. Circulation 2003;108:1954-9.
12. van den Heuvel AF, van Veldhuisen DJ, van der Wall EE, et al. Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 2000;35:19-28.
13. 123I-mIBG scintigraphy to predict risk for adverse cardiac outcomes in heart failure patients: Design of two prospective multicenter international trials. J Nucl Cardiol 2009;16:113-21.
14. Cerqueira MD, Weissman NJ, Dilsizian V, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation 2002;105:539-42.
15. Sharir T, Berman DS, Lewin HC, et al. Incremental prognostic value of rest-redistribution (201)Tl single-photon emission computed tomography. Circulation 1999;100:1964-70.
16. Dunn RF, Uren RF, Sadick N, et al. Comparison of thallium-201 scanning in idiopathic dilated cardiomyopathy and severe coronary artery disease. Circulation 1982;66:804-10.
17. Borges-Neto S, Shaw LK, Tuttle RH, et al. Incremental prognostic power of single-photon emission computed tomographic myocardial perfusion imaging in patients with known or suspected coronary artery disease. Am J Cardiol 2005;95:182-8.
18. Nishisato K, Hashimoto A, Nakata T, et al. Impaired cardiac sympathetic innervation and myocardial perfusion are related to lethal arrhythmia: Quantification of cardiac tracers in patients with ICDs. J Nucl Med 2010;51:1241-9.
19. Backs J, Haunstetter A, Gerber SH, et al. The neuronal norepinephrine transporter in experimental heart failure: Evidence for a posttranscriptional downregulation. J Mol Cell Cardiol 2001;33:461-72.
20. Brunner-La Rocca HP, Esler MD, Jennings GL, Kaye DM. Effect of cardiac sympathetic nervous activity on mode of death in congestive heart failure. Eur Heart J 2001;22:1136-43.
21. Danias PG, Ahlberg AW, Clark BA 3rd, et al. Combined assessment of myocardial perfusion and left ventricular function with exercise technetium-99m sestamibi gated single-photon emission computed tomography can differentiate between ischemic and nonischemic dilated cardiomyopathy. Am J Cardiol 1998;82:1253-8.
22. Pitcher D, Wainwright R, Maisey M, Curry P, Sowton E. Assessment of chest pain in hypertrophic cardiomyopathy using exercise thallium-201 myocardial scintigraphy. Br Heart J 1980;44:650-6.
23. Soman P, Lahiri A, Mieres JH, et al. Etiology and pathophysiology of new-onset heart failure: Evaluation by myocardial perfusion imaging. J Nucl Cardiol 2009;16:82-91.