Insulin hypersecretion in islets from diet-induced hyperinsulinemic obese female mice is associated with several functional adaptations in individual β-cells

Endocrinology

Volumn 154, Issue 10, 2013, Pages 3515-3524

  Gonzalez, Alejandro ^a,b   Merino, Beatriz ^a,b   Marroquí, Laura ^a,b   Ñeco, Patricia ^a,b   Alonso Magdalena, Paloma ^a,b   Caballero Garrido, Ernesto ^a,b   Vieira, Elaine ^a,b,c   Soriano, Sergi ^d   Gomis, Ramon ^b,c,e   Nadal, Angel ^a,b   Quesada, Ivan ^a,b  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d UNIVERSITY OF ALICANTE   (Spain)

^e UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL POPULATION; CONTROLLED STUDY; DEPOLARIZATION; EXOCYTOSIS; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HYPERINSULINEMIA; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID DIET; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ACTION POTENTIALS; ALLOSTASIS; ANIMALS; CALCIUM SIGNALING; CELL SIZE; CELLS, CULTURED; DIET, HIGH-FAT; ELECTRIC CONDUCTIVITY; EXOCYTOSIS; FEMALE; GLUCOSE INTOLERANCE; HYPERINSULINISM; HYPERTROPHY; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; KATP CHANNELS; MICE; MICE, INBRED C57BL; OBESITY; UP-REGULATION;

EID: 84884677487     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1424     Document Type: Article

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