The prevalence of fat-soluble vitamin deficiencies and a decreased bone mass in patients with chronic pancreatitis

Pancreatology

Volumn 13, Issue 3, 2013, Pages 238-242

  Sikkens, Edmée C M ^a   Cahen, Djuna L ^a   Koch, Arjun D ^a   Braat, Henri ^a   Poley, Jan Werner ^a   Kuipers, Ernst J ^a   Bruno, Marco J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Bone loss; Chronic pancreatitis; Exocrine pancreatic insufficiency; Fat soluble vitamins; Pancreatic enzyme supplementation

Indexed keywords

ALPHA TOCOPHEROL; PANCREAS ENZYME; RETINOL; VITAMIN D; VITAMIN K GROUP;

ADULT; ALCOHOL ABUSE; ALPHA TOCOPHEROL DEFICIENCY; ARTICLE; BONE DENSITOMETRY; BONE MASS; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; OSTEOPENIA; OSTEOPOROSIS; PANCREAS EXOCRINE INSUFFICIENCY; PANCREAS FUNCTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETINOL DEFICIENCY; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN DEFICIENCY; VITAMIN K DEFICIENCY;

EID: 84884671075     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1016/j.pan.2013.02.008     Document Type: Article

References (49)

1. Nair RJ, Lawler L, Miller MR. Chronic pancreatitis. Am Fam Physician 2007;76: 1679-88.
2. Lankisch PG, Lembcke B, Wemken G, Creutzfeldt W. Functional reserve capacity of the exocrine pancreas. Digestion 1986;35:175-81.
3. Layer P, Go VL, DiMagno EP. Fate of pancreatic enzymes during small intestinal aboral transit in humans. Am J Physiol 1986;251:G475-80.
4. Layer P, Keller J. Pancreatic enzymes: secretion and luminal nutrient digestion in health and disease. J Clin Gastroenterol 1999;28:3-10.
5. Layer PH, DiMagno EP. Natural histories of alcoholic and idiopathic chronic pancreatitis. Pancreas 1996;12:318-20.
6. Pasquali C, Fogar P, Sperti C, Basso D, De Paoli M, Plebani M, et al. Efficacy of a pancreatic enzyme formulation in the treatment of steatorrhea in patients with chronic pancreatitis. Curr Ther Res Clin Exp 1996;57:358-65.
7. Rivers JP, Hassam AG. Defective essential-fatty-acid metabolism in cystic fibrosis. Lancet 1975;2:642-3.
8. Roberts IM. Enzyme therapy for malabsorption in exocrine pancreatic insufficiency. Pancreas 1989;4:496-503.
9. Rosenlund ML, Kim HK, Kritchevsky D. Essential fatty acids in cystic fibrosis. Nature 1974;251:719.
10. Dutta SK, Bustin MP, Russell RM, Costa BS. Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency. Ann Intern Med 1982;97: 549-52.
11. Kalivianakis M, Minich DM, Bijleveld CM, van Aalderen WM, Stellaard F, Laseur M, et al. Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. Am J Clin Nutr 1999;69:127-34.
12. Lankisch PG, Lembcke B, Goke B, Creutzfeldt W. Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage? Z Gastroenterol 1986;24:753-7.
13. Conway SP, Wolfe SP, Brownlee KG, White H, Oldroyd B, Truscott JG, et al. Vitamin K status among children with cystic fibrosis and its relationship to bone mineral density and bone turnover. Pediatrics 2005;115:1325-31.
14. Gundberg CM, Nieman SD, Abrams S, Rosen H. Vitamin K status and bone health: an analysis of methods for determination of undercarboxylated osteocalcin. J Clin Endocrinol Metab 1998;83:3258-66.
15. Shearer MJ. Vitamin K. Lancet 1995;345:229-34.
16. Vermeer C, Knapen MH, Schurgers LJ. Vitamin K and metabolic bone disease. J Clin Pathol 1998;51:424-6.
17. Haaber AB, Rosenfalck AM, Hansen B, Hilsted J, Larsen S. Bone mineral metabolism, bone mineral density, and body composition in patients with chronic pancreatitis and pancreatic exocrine insufficiency. Int J Pancreatol 2000;27:21-7.
18. Moran CE, Sosa EG, Martinez SM, Geldern P, Messina D, Russo A, et al. Bone mineral density in patients with pancreatic insufficiency and steatorrhea. Am J Gastroenterol 1997;92:867-71.
19. Catignani GL, Bieri JG. Simultaneous determination of retinol and alphatocopherol in serum or plasma by liquid chromatography. Clin Chem 1983;29:708-12.
20. Van Haard PM, Engel R, Postma T. Routine clinical determination of carotene, vitamin E, vitamin A, 25-hydroxy vitamin D3 and trans-vitamin K1 in human serum by straight phase HPLC. Biomed Chromatogr 1987;2: 79-88.
21. Janssen MJ, Wielders JP, Bekker CC, Boesten LS, Buijs MM, Heijboer AC, et al. Multicenter comparison study of current methods to measure 25-hydroxyvitamin D in serum. Steroids 2012;77:1366-72.
22. Blokstra WMMV A, Baen CA, Boshuizen HC, Feenstra TL, Hoogenveen RT, Picavet HSJ, et al. Vergrijzing en toekomstige ziektelast; Prognose chronische ziekte prevalentie 2005-2025. 98, http://www.rivm.nl/bibliotheek/rapporten/ 260401004.pdf; 2007.
23. Hd Valk. Voorkomen osteoporose in Nederland. vol. 2013. http://www.cbbr.nl/nieuws-osteopenie.html; 2005.
24. Volksgezondheid NK. Hoe vaak komt osteoporose voor en hoeveel mensen sterven eraan?. 4.10 ed. vol. 2013. Bilthoven, http://www.nationaalkompas.nl/ gezondheid-en-ziekte/ziekten-en-aandoeningen/bewegingsstelsel-en-bindweefsel/ osteoporose/omvang/; 2012.
25. Bauss F, Minne HW, Sterz H, Weng U, Wesch H, Ziegler R. Comparative bone analysis via inflammation-mediated osteopenia (IMO) in the rat. Calcif Tissue Int 1985;37:539-46.
26. Pfeilschifter J, Minne HW, Enzmann E, Krempien B, Ziegler R. Inflammation-mediated osteopenia in the rat: the effects of artificial granuloma and sham operation on cortical and trabecular bone. Bone 1985;6:461-5.
27. Bernstein CN, Leslie WD. The pathophysiology of bone disease in gastrointestinal disease. Eur J Gastroenterol Hepatol 2003;15:857-64.
28. Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Hamada S, et al. Fibrinogen induces cytokine and collagen production in pancreatic stellate cells. Gut 2009;58:550-9.
29. Talukdar R, Tandon RK. Pancreatic stellate cells: new target in the treatment of chronic pancreatitis. J Gastroenterol Hepatol 2008;23:34-41.
30. Tilg H, Moschen AR, Kaser A, Pines A, Dotan I. Gut, inflammation and osteoporosis: basic and clinical concepts. Gut 2008;57:684-94.
31. IMvd Meer. Vitamine D-tekort in een multi-etnische populatie; determinanten, prevalentie en consequenties. Epidemiol Bull 2010;45:2-6.
32. IMvd Meer. Is er samenhang tussen de vitamine D-status en diabetes bij nietwesterse allochtonen? Epidemiol Bull 2008;43:10-3.
33. Kuchuk NO, Pluijm SM, van Schoor NM, Looman CW, Smit JH, Lips P. Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons. J Clin Endocrinol Metab 2009;94:1244-50.
34. Lips P, Duong T, Oleksik A, Black D, Cummings S, Cox D, et al. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. J Clin Endocrinol Metab 2001;86: 1212-21.
35. van der Meer IM, Boeke AJ, Lips P, Grootjans-Geerts I, Wuister JD, Deville WL, et al. Fatty fish and supplements are the greatest modifiable contributors to the serum 25-hydroxyvitamin D concentration in a multiethnic population. Clin Endocrinol 2008;68:466-72.
36. Marotta F, Labadarios D, Frazer L, Girdwood A, Marks IN. Fat-soluble vitamin concentration in chronic alcohol-induced pancreatitis. Relationship with steatorrhea. Dig Dis Sci 1994;39:993-8.
37. Mosler K, von Kries R, Vermeer C, Saupe J, Schmitz T, Schuster A. Assessment of vitamin K deficiency in CF - how much sophistication is useful? J Cyst Fibros 2003;2:91-6.
38. Wilson DC, Rashid M, Durie PR, Tsang A, Kalnins D, Andrew M, et al. Treatment of vitamin K deficiency in cystic fibrosis: effectiveness of a daily fatsoluble vitamin combination. J Pediatr 2001;138:851-5.
39. Dominguez-Munoz JE, Iglesias-Garcia J. Oral pancreatic enzyme substitution therapy in chronic pancreatitis: is clinical response an appropriate marker for evaluation of therapeutic efficacy? JOP 2010;11:158-62.
40. Mann ST, Stracke H, Lange U, Klor HU, Teichmann J. Alterations of bone mineral density and bone metabolism in patients with various grades of chronic pancreatitis. Metabolism 2003;52:579-85.
41. Dujsikova H, Dite P, Tomandl J, Sevcikova A, Precechtelova M. Occurrence of metabolic osteopathy in patients with chronic pancreatitis. Pancreatology 2008;8:583-6.
42. Sudeep K, Chacko A, Thomas N, Selvakumar R, George B, Paul TV, et al. Predictors of osteodystrophy in patients with chronic nonalcoholic pancreatitis with or without diabetes. Endocr Pract 2011;17:897-905.
43. van Staa TP, Dennison EM, Leufkens HG, Cooper C. Epidemiology of fractures in England and Wales. Bone 2001;29:517-22.
44. Boulton-Jones JR, Fenn RM, West J, Logan RF, Ryder SD. Fracture risk of women with primary biliary cirrhosis: no increase compared with general population controls. Aliment Pharmacol Ther 2004;20:551-7.
45. Tignor AS, Wu BU, Whitlock TL, Lopez R, Repas K, Banks PA, et al. High prevalence of low-trauma fracture in chronic pancreatitis. Am J Gastroenterol 2010;105:2680-6.
46. Dominguez-Munoz JE. Pancreatic enzyme therapy for pancreatic exocrine insufficiency. Curr Gastroenterol Rep 2007;9:116-22.
47. Dominguez-Munoz JE, Iglesias-Garcia J, Vilarino-Insua M, Iglesias-Rey M. 13Cmixed triglyceride breath test to assess oral enzyme substitution therapy in patients with chronic pancreatitis. Clin Gastroenterol Hepatol 2007;5:484-8.
48. Dominguez-Munoz JE. Pancreatic enzyme replacement therapy: exocrine pancreatic insufficiency after gastrointestinal surgery. HPB (Oxford) 2009;11(Suppl. 3):3-6.
49. Bang Jorgensen B, Thorsgaard Pedersen N, Worning H. Short report: lipid and vitamin B12 malassimilation in pancreatic insufficiency. Aliment Pharmacol Ther 1991;5:207-10.