Physical hydrogels composed of polyampholytes demonstrate high toughness and viscoelasticity

Nature Materials

Volumn 12, Issue 10, 2013, Pages 932-937

  Sun, Tao Lin ^a   Kurokawa, Takayuki ^a   Kuroda, Shinya ^a   Ihsan, Abu Bin ^a   Akasaki, Taigo ^a   Sato, Koshiro ^a   Haque, Md Anamul ^a   Nakajima, Tasuku ^a   Gong, Jian Ping ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL TISSUES; DISTRIBUTION OF STRENGTH; HIGH TOUGHNESS; IONIC BONDS; POLYAMPHOLYTES; SELF-HEALING; SUPRAMOLECULAR STRUCTURE; VISCOELASTIC HYDROGELS;

BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; CROSSLINKING; ELASTICITY; IONIC STRENGTH; STIFFNESS; TOUGHNESS;

HYDROGELS;

BIOMATERIAL; ELECTROLYTE;

ARTICLE; CHEMISTRY; ELASTICITY; ELECTRON; HYDROGEL; POLYMERIZATION; TENSILE STRENGTH; VISCOSITY;

BIOCOMPATIBLE MATERIALS; ELASTICITY; ELECTROLYTES; ELECTRONS; HYDROGELS; POLYMERIZATION; TENSILE STRENGTH; VISCOSITY;

EID: 84884596662     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat3713     Document Type: Article

References (37)

1. Yasuda, K. et al. A novel double-network hydrogel induces spontaneous articular cartilage regeneration in vivo in a large osteochondral defect. Macromol. Biosci. 9, 307-316 (2009).
2. Drury, J. L. & Mooney, D. J. Hydrogels for tissue engineering: Scaffold design variables and applications. Biomaterials 24, 4337-4351 (2003).
3. Bodugoz-Senturk, H., Macias, C. E., Kung, J. H. & Muratoglu, O. K. Poly(vinyl alcohol)-acrylamide hydrogels as load-bearing cartilage substitute. Biomaterials 30, 589-596 (2009).
4. Tanaka, Y., Fukao, K. & Miyamoto, Y. Fracture energy of gels. Eur. Phys. J. E 3, 395-401 (2000).
5. Baumberger, T., Caroli, C. & Martina, D. Solvent control of crack dynamics in a reversible hydrogel. Nature Mater. 5, 552-555 (2006).
6. Naficy, S., Brown, H. R., Razal, J. M., Spinks, G. M. & Whitten, P. G. Progress toward robust polymer hydrogels. Aust. J. Chem. 64, 1007-1025 (2011).
7. Haraguchi, K. & Takehisa, T. Nanocomposite hydrogels: A unique organic-inorganic network structure with extraordinary mechanical, optical, and swelling/de-swelling properties. Adv. Mater. 14, 1120-1124 (2002).
8. Gong, J. P., Katsuyama, Y., Kurokawa, T. & Osada, Y. Double-network hydrogels with extremely high mechanical strength. Adv. Mater. 15, 1155-1158 (2003).
9. Huang, T. et al. A novel hydrogel with high mechanical strength: A macromolecular microsphere composite hydrogel. Adv. Mater. 19, 1622-1626 (2007).
10. Moutos, F. T., Freed, L. E. & Guilak, F. A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage. Nature Mater 6, 162-167 (2007).
11. Fung, Y. C. Biomechanics: Mechanical Properties of Living Tissues 2nd edn (Springer, 1993).
12. Gong, J. P. Why are double network hydrogels so tough? Soft Matter 6, 2583-2590 (2010).
13. Na, Y. H. et al. Necking phenomenon of double-network gels. Macromolecules 39, 4641-4645 (2006).
14. Webber, R. E., Creton, C., Brown, H. R. & Gong, J. P. Large strain hysteresis and mullins effect of tough double-network hydrogels. Macromolecules 40, 2919-2927 (2007).
15. Fantner, G. E. et al. Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture. Nature Mater. 4, 612-616 (2005).
16. Henderson, K. J., Zhou, T. C., Otim, K. J. & Shull, K. R. Ionically cross-linked triblock copolymer hydrogels with high strength. Macromolecules 43, 6193-6201 (2010).
17. Haque, M. A., Kurokawa, T., Kamita, G. & Gong, J. P. Lamellar bilayers as reversible sacrificial bonds to toughen hydrogel: Hysteresis, self-recovery, fatigue resistance, and crack blunting. Macromolecules 44, 8916-8924 (2011).
18. Sun, J. Y. et al. Highly stretchable and tough hydrogels. Nature 489, 133-136 (2012).
19. Higgs, P. G. & Joanny, J. F. Theory of polyampholyte solutions. J. Chem. Phys. 94, 1543-1554 (1991).
20. Kudaibergenov, S. E. Recent advances in the study of synthetic polyampholytes in solutions. Adv. Polym. Sci. 144, 115-197 (1999).
21. Nisato, G., Munch, J. P. & Candau, S. J. Swelling, structure, and elasticity of polyampholyte hydrogels. Langmuir 15, 4236-4244 (1999).
22. Pafiti, K. S., Philippou, Z., Loizou, E., Porcar, L. & Patrickios, C. S. End-linked poly[2-(dimethylamino)ethyl methacrylate]-poly(methacrylic acid) polyampholyte conetworks: Synthesis by sequential raft polymerization and swelling and sans characterization. Macromolecules 44, 5352-5362 (2011).
23. Takeoka, Y. et al. First order phase transition and evidence for frustrations in polyampholytic gels. Phys. Rev. Lett. 82, 4863-4865 (1999).
24. Zavitsas, A. A. Quantitative relationship between bond dissociation energies, infrared stretching frequencies, and force-constants in polyatomic molecules. J. Phys. Chem. 91, 5573-5577 (1987).
25. Holyst, R. Some features of soft matter systems. Soft Matter 1, 329-333 (2005).
26. Yu, Q. M., Tanaka, Y., Furukawa, H., Kurokawa, T. & Gong, J. P. Direct observation of damage zone around crack tips in double-network gels. Macromolecules 42, 3852-3855 (2009).
27. Persson, B. N. J. & Brener, E. A. Crack propagation in viscoelastic solids. Phys. Rev. E 71, 036123 (2005).
28. Varley, R. J., Shen, S. & van der Zwaag, S. The effect of cluster plasticisation on the self healing behaviour of ionomers. Polymer 51, 679-686 (2010).
29. Nakajima, T. et al. True chemical structure of double network hydrogels. Macromolecules 42, 2184-2189 (2009).
30. Bauer, A. M., Russell, A. P. & Shadwick, R. E. Mechanical properties and morphological correlates of fragile skin in gekkonid lizards. J. Exp. Biol. 145, 79-102 (1989).
31. Taylor, D., O'Mara, N., Ryan, E., Takaza, M. & Simms, C. The fracture toughness of soft tissues. J. Mech. Behav. Biomed. Mater. 6, 139-147 (2012).
32. Wang, Q. et al. High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder. Nature 463, 339-343 (2010).
33. Nakahata, M., Takashima, Y., Yamaguchi, H. & Harada, A. Redox-responsive self-healing materials formed from host-guest polymers. Nature Commun. 2, 511-516 (2011).
34. Zhang, M. M. et al. Self-healing supramolecular gels formed by crown ether based host-guest interactions. Angew. Chem. Int. Ed. 51, 7011-7015 (2012).
35. Cordier, P., Tournilhac, F., Soulié-Ziakovic, C. & Leibler, L. Self-healing and thermoreversible rubber from supramolecular assembly. Nature 451, 977-980 (2008).
36. Tanaka, Y. et al. Determination of fracture energy of high strength double network hydrogels. J. Phys. Chem. B 109, 11559-11562 (2005).
37. Rivlin, R. S. & Thomas, A. G. Rupture of rubber. I. Characteristic energy for tearing. J. Polym. Sci. 10, 291-318 (1953).