HLA-DQB1*02 and DQB1*06:03P are associated with peanut allergy

European Journal of Human Genetics

Volumn 21, Issue 10, 2013, Pages 1181-1184

  Madore, Anne Marie ^a   Vaillancourt, Vanessa T ^a   Asai, Yuka ^b   Alizadehfar, Reza ^b   Ben Shoshan, Moshe ^b   Michel, Deborah L ^c   Kozyrskyj, Anita L ^d,e   Becker, Allan ^e   Chan Yeung, Moira ^f   Clarke, Ann E ^g   Hull, Peter ^c   Daley, Denise ^f   Sandford, Andrew J ^f   Laprise, Catherine ^a  

^a UNIVERSITÉ DU QUÉBEC À CHICOUTIMI   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

^e UNIVERSITY OF MANITOBA   (Canada)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

association; Caucasian; food allergy; HLA DQB1; peanut allergy

Indexed keywords

HLA DQB1 ANTIGEN; HLA DQ ANTIGEN; HLA-DQB1 ANTIGEN;

ALLELE; ARTICLE; CAUCASIAN; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PEANUT ALLERGY; PRIORITY JOURNAL; SCHOOL CHILD; SEX DIFFERENCE; CASE CONTROL STUDY; GENETIC ASSOCIATION STUDY; GENETICS; PRESCHOOL CHILD;

ARACHIS HYPOGAEA;

ALLELES; CASE-CONTROL STUDIES; CHILD, PRESCHOOL; FEMALE; GENETIC ASSOCIATION STUDIES; HLA-DQ BETA-CHAINS; HUMANS; MALE; PEANUT HYPERSENSITIVITY;

EID: 84884595586     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2013.13     Document Type: Article

References (17)

1. Hourihane JO: Peanut allergy. Pediatr Clin North Am 2011; 58: 445-458, xi
2. Ben-Shoshan M, Harrington DW, Soller L et al: A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada. J Allergy Clin Immunol 2010; 125: 1327-1335
3. Moffatt MF, Gut IG, Demenais F et al: A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010; 363: 1211-1221
4. Simpson AB, Yousef E, Hossain J: Association between peanut allergy and asthma morbidity. J Pediatr 2010; 156: 781. e771
5. Shreffler WG, Charlop-Powers Z, Sicherer SH: Lack of association of HLA class II alleles with peanut allergy. Ann Allergy Asthma Immunol 2006; 96: 865-869
6. Dreskin SC, Tripputi MT, Aubrey MT et al: Peanut-allergic subjects and their peanuttolerant siblings have large differences in peanut-specific IgG that are independent of HLA class II. Clin Immunol 2010; 137: 366-373
7. Howell WM, Turner SJ, Hourihane JO, Dean TP, Warner JO: HLA class II DRB1, DQB1 and DPB1 genotypic associations with peanut allergy: Evidence from a family-based and case-control study. Clin Exp Allergy 1998; 28: 156-162
8. Nguyen-Luu NU, Ben-Shoshan M, Alizadehfar R et al: Inadvertent exposures in children with peanut allergy. Pediatr Allergy Immunol 2012; 23: 133-139
9. Chan-Yeung M, Manfreda J, Dimich-Ward H, Ferguson A, Watson W, Becker A: A randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants. Arch Pediatr Adolesc Med 2000; 154: 657-663
10. Liem JJ, Huq S, Kozyrskyj AL, Becker AB: Should younger siblings of peanut-allergic children be assessed by an allergist before being fed peanut? Allergy Asthma Clin Immunol 2008; 4: 144-149
11. Robinson J, Halliwell JA, McWilliam H, Lopez R, Parham P, Marsh SGE: The IMGT/HLA Database. Nucleic Acids Research 2013; 41: D1222-D1227
12. Robinson J, Malik A, Parham P, Bodmer JG, Marsh SGE: IMGT/HLA - a sequence database for the human major histocompatibility complex. Tissue Antigens 2000; 55: 280-287
13. Hollenbach JA, Mack SJ, Gourraud PA et al: A community standard for immunogenomic data reporting and analysis: Proposal for a STrengthening the REporting of Immunogenomic Studies statement. Tissue Antigens 2011; 78: 333-344
14. HLA nomenclature: Nomenclature for factors of the HLA system; 2012; Accessed on September 2012. http://hla.alleles.org/alleles/p-groups.html
15. Heinze G, Schemper M: A solution to the problem of separation in logistic regression. Stat Med 2002; 21: 2409-2419
16. Miretti MM, Walsh EC, Ke X et al: A high-resolution linkage- disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet 2005; 76: 634-646
17. Ramagopalan SV, Ebers GC: Multiple sclerosis: Major histocompatibility complexity and antigen presentation. Genome Med 2009; 1: 105