Punctate lesion pattern suggestive of perivascular inflammation in acute natalizumab-associated progressive multifocal leukoencephalopathy: Productive JC virus infection or preclinical PML-IRIS manifestation?

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 84, Issue 10, 2013, Pages 1176-1177

  Wattjes, Mike P ^a   Verhoeff, Lonneke ^b   Zentjens, Willemijn ^b   Killestein, Joep ^a   Van Munster, Erik T ^b   Barkhof, Frederik ^a   Van Eijk, Jeroen J J ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b JEROEN BOSCH HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DNA; MEFLOQUINE; METHYLPREDNISOLONE; MIRTAZAPINE; NATALIZUMAB;

ADULT; ATAXIA; CASE REPORT; CEREBROSPINAL FLUID CYTOLOGY; CLINICAL FEATURE; CONTRAST ENHANCEMENT; DISEASE ASSOCIATION; DISEASE COURSE; DNA DETERMINATION; DNA VIRUS; FEMALE; GENERAL CONDITION DETERIORATION; HUMAN; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; JC VIRUS; LETTER; LUMBAR PUNCTURE; MULTIPLE SCLEROSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIVASCULAR INFLAMMATION; PLASMAPHERESIS; PNEUMONIA; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; REAL TIME POLYMERASE CHAIN REACTION; SLURRED SPEECH; TREATMENT RESPONSE; TREATMENT WITHDRAWAL; VIRUS INFECTION; WHITE MATTER LESION;

EID: 84884593714     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2013-304986     Document Type: Letter

References (5)

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3. Kleinschmidt-DeMasters BK, Miravalle A, Schowinsky J, et al. Update on PML and PML-IRIS occurring in multiple sclerosis patients treated with natalizumab. J Neuropathol Exp Neurol 2012; 71: 604-17.
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5. Yousry TA, Pelletier D, Cadavid D, et al. MRI pattern in natalizumab-associated progressive multifocal leukoencephalopathy. Ann Neurol 2012; 72: 779-87.