-
1
-
-
0035991260
-
Genetic and environmental determinants of peak bone mass in young men and women
-
McGuigan FE, Murray L, Gallagher A, Davey-Smith G, Neville CE, et al. (2002) Genetic and environmental determinants of peak bone mass in young men and women. J Bone Miner Res 17: 1273-1279.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1273-1279
-
-
McGuigan, F.E.1
Murray, L.2
Gallagher, A.3
Davey-Smith, G.4
Neville, C.E.5
-
2
-
-
0028060362
-
The diagnosis of osteoporosis
-
Kanis JA, Melton III LJ, Christiansen J, Johnston CC, Khaltaev N, (1994) The diagnosis of osteoporosis. J Bone Miner Res 9: 1137-1141.
-
(1994)
J Bone Miner Res
, vol.9
, pp. 1137-1141
-
-
Kanis, J.A.1
Melton III, L.J.2
Christiansen, J.3
Johnston, C.C.4
Khaltaev, N.5
-
3
-
-
84857064587
-
Absolute fracture-risk prediction by a combination of calcaneal quantitative ultrasound and bone mineral density
-
Chan MY, Nguyen ND, Center JR, Eisman JA, Nguyen TV, (2012) Absolute fracture-risk prediction by a combination of calcaneal quantitative ultrasound and bone mineral density. Calcif Tissue Int 90: 128-136.
-
(2012)
Calcif Tissue Int
, vol.90
, pp. 128-136
-
-
Chan, M.Y.1
Nguyen, N.D.2
Center, J.R.3
Eisman, J.A.4
Nguyen, T.V.5
-
4
-
-
0030678549
-
Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G, (1997) Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89: 747-754.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
5
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, et al. (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89: 755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
-
6
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, et al. (1997) Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89: 765-771.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
-
7
-
-
15444351110
-
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia
-
Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, et al. (1997) Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell 89: 773-779.
-
(1997)
Cell
, vol.89
, pp. 773-779
-
-
Mundlos, S.1
Otto, F.2
Mundlos, C.3
Mulliken, J.B.4
Aylsworth, A.S.5
-
8
-
-
84255200563
-
Building strong bones: molecular regulation of the osteoblast lineage
-
Long F, (2011) Building strong bones: molecular regulation of the osteoblast lineage. Nat Rev Mol Cell Biol 13: 27-38.
-
(2011)
Nat Rev Mol Cell Biol
, vol.13
, pp. 27-38
-
-
Long, F.1
-
9
-
-
33745959553
-
Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development
-
Kanatani N, Fujita T, Fukuyama R, Liu W, Yoshida CA, et al. (2006) Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development. Dev Biol 296: 48-61.
-
(2006)
Dev Biol
, vol.296
, pp. 48-61
-
-
Kanatani, N.1
Fujita, T.2
Fukuyama, R.3
Liu, W.4
Yoshida, C.A.5
-
10
-
-
0036781942
-
Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations
-
Yoshida T, Kanegane H, Osato M, Yanagida M, Miyawaki T, et al. (2002) Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations. Am J Hum Genet 71: 724-738.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 724-738
-
-
Yoshida, T.1
Kanegane, H.2
Osato, M.3
Yanagida, M.4
Miyawaki, T.5
-
11
-
-
84884581840
-
-
Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD). Available:, CLEIDOCRANIAL DYSPLASIA; CCD. Accessed 2012
-
Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD). Available: http://omim.org/#119600, CLEIDOCRANIAL DYSPLASIA; CCD. Accessed 2012.
-
-
-
-
13
-
-
22144436962
-
Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice
-
Xiao Z, Awad HA, Liu S, Mahlios J, Zhang S, et al. (2005) Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice. Dev Biol 283: 345-356.
-
(2005)
Dev Biol
, vol.283
, pp. 345-356
-
-
Xiao, Z.1
Awad, H.A.2
Liu, S.3
Mahlios, J.4
Zhang, S.5
-
14
-
-
80051924950
-
Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation
-
Liu JC, Lengner CJ, Gaur T, Lou Y, Hussain S, et al. (2011) Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation. J Biol Chem 286: 30057-30070.
-
(2011)
J Biol Chem
, vol.286
, pp. 30057-30070
-
-
Liu, J.C.1
Lengner, C.J.2
Gaur, T.3
Lou, Y.4
Hussain, S.5
-
15
-
-
0031877209
-
The exclusion of high trauma fractures may underestimate the prevalence of bone fragility fractures in the community: the Geelong Osteoporosis Study
-
Sanders KM, Pasco JA, Ugoni AM, Nicholson GC, Seeman E, et al. (1998) The exclusion of high trauma fractures may underestimate the prevalence of bone fragility fractures in the community: the Geelong Osteoporosis Study. J Bone Miner Res 13: 1337-1342.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1337-1342
-
-
Sanders, K.M.1
Pasco, J.A.2
Ugoni, A.M.3
Nicholson, G.C.4
Seeman, E.5
-
16
-
-
0033738714
-
Prevalence of osteoporosis in Australian women: Geelong osteoporosis study
-
Henry MJ, Pasco JA, Seeman E, Nicholson GC, Kotowicz MA, (2000) Prevalence of osteoporosis in Australian women: Geelong osteoporosis study. J Clin Densitom 3: 261-268.
-
(2000)
J Clin Densitom
, vol.3
, pp. 261-268
-
-
Henry, M.J.1
Pasco, J.A.2
Seeman, E.3
Nicholson, G.C.4
Kotowicz, M.A.5
-
17
-
-
0026586120
-
New approaches for interpreting projected bone densitometry data
-
Carter DR, Bouxsein ML, Marcus R, (1992) New approaches for interpreting projected bone densitometry data. J Bone Miner Res 7: 137-145.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 137-145
-
-
Carter, D.R.1
Bouxsein, M.L.2
Marcus, R.3
-
18
-
-
0032901943
-
Identification of incident fractures: the Geelong Osteoporosis Study
-
Pasco JA, Henry MJ, Gaudry T, Nicholson GC, Kotowicz MA, (1999) Identification of incident fractures: the Geelong Osteoporosis Study. Aust N Z J Med 29: 203-206.
-
(1999)
Aust N Z J Med
, vol.29
, pp. 203-206
-
-
Pasco, J.A.1
Henry, M.J.2
Gaudry, T.3
Nicholson, G.C.4
Kotowicz, M.A.5
-
19
-
-
0032875190
-
Age- and gender-specific rate of fractures in Australia: a population-based study
-
Sanders KM, Seeman E, Ugoni AM, Pasco JA, Martin TJ, et al. (1999) Age- and gender-specific rate of fractures in Australia: a population-based study. Osteoporos Int 10: 240-247.
-
(1999)
Osteoporos Int
, vol.10
, pp. 240-247
-
-
Sanders, K.M.1
Seeman, E.2
Ugoni, A.M.3
Pasco, J.A.4
Martin, T.J.5
-
20
-
-
0033984390
-
Serum CTX: a new marker of bone resorption that shows treatment effect more often than other markers because of low coefficient of variability and large changes with bisphosphonate therapy
-
Rosen HN, Moses AC, Garber J, Iloputaife ID, Ross DS, et al. (2000) Serum CTX: a new marker of bone resorption that shows treatment effect more often than other markers because of low coefficient of variability and large changes with bisphosphonate therapy. Calcif Tissue Int 66: 100-103.
-
(2000)
Calcif Tissue Int
, vol.66
, pp. 100-103
-
-
Rosen, H.N.1
Moses, A.C.2
Garber, J.3
Iloputaife, I.D.4
Ross, D.S.5
-
21
-
-
84855678849
-
Bone turnover markers for osteoporotic status assessment? A systematic review of their diagnosis value at baseline in osteoporosis
-
Biver E, Chopin F, Coiffier G, Brentano TF, Bouvard B, et al. (2012) Bone turnover markers for osteoporotic status assessment? A systematic review of their diagnosis value at baseline in osteoporosis. Joint Bone Spine 79: 20-25.
-
(2012)
Joint Bone Spine
, vol.79
, pp. 20-25
-
-
Biver, E.1
Chopin, F.2
Coiffier, G.3
Brentano, T.F.4
Bouvard, B.5
-
22
-
-
0035992658
-
Alleles of RUNX2/CBFA1 gene are associated with differences in bone mineral density and risk of fracture
-
Vaughan T, Pasco JA, Kotowicz MA, Nicholson GC, Morrison NA, (2002) Alleles of RUNX2/CBFA1 gene are associated with differences in bone mineral density and risk of fracture. J Bone Miner Res 17: 1527-1534.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1527-1534
-
-
Vaughan, T.1
Pasco, J.A.2
Kotowicz, M.A.3
Nicholson, G.C.4
Morrison, N.A.5
-
23
-
-
0034641617
-
A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia
-
Zhang YW, Yasui N, Ito K, Huang G, Fujii M, et al. (2000) A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia. Proc Natl Acad Sci USA 97: 10549-10554.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10549-10554
-
-
Zhang, Y.W.1
Yasui, N.2
Ito, K.3
Huang, G.4
Fujii, M.5
-
24
-
-
84865060439
-
Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation
-
Morrison NA, Stephens AS, Osato M, Polly P, Tan TC, et al. (2012) Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation. Plos_ONE 7 (8) (): e42617.
-
(2012)
Plos_ONE
, vol.7
, Issue.8
-
-
Morrison, N.A.1
Stephens, A.S.2
Osato, M.3
Polly, P.4
Tan, T.C.5
-
25
-
-
0034660683
-
A noncommercial dual luciferase enzyme assay system for reporter gene analysis
-
Dyer BW, Ferrer FA, Klinedinst DK, Rodriguez R, (2000) A noncommercial dual luciferase enzyme assay system for reporter gene analysis. Anal Biochem 282: 158-161.
-
(2000)
Anal Biochem
, vol.282
, pp. 158-161
-
-
Dyer, B.W.1
Ferrer, F.A.2
Klinedinst, D.K.3
Rodriguez, R.4
-
26
-
-
77952136530
-
A draft sequence of the Neandertal genome
-
Green RE, Krause J, Briggs AW, Maricic T, Stenzel U, et al. (2010) A draft sequence of the Neandertal genome. Science 328: 710-722.
-
(2010)
Science
, vol.328
, pp. 710-722
-
-
Green, R.E.1
Krause, J.2
Briggs, A.W.3
Maricic, T.4
Stenzel, U.5
-
27
-
-
84555206233
-
On characterizing adaptive events unique to modern humans
-
Crisci JL, Wong A, Good JM, Jensen JD, (2011) On characterizing adaptive events unique to modern humans. Genome Biol Evol 3: 791-798.
-
(2011)
Genome Biol Evol
, vol.3
, pp. 791-798
-
-
Crisci, J.L.1
Wong, A.2
Good, J.M.3
Jensen, J.D.4
-
28
-
-
84867331947
-
A high-coverage genome sequence from an archaic Denisovan individual
-
Meyer M, Kircher M, Gansauge MT, Li H, Racimo F, et al. (2012) A high-coverage genome sequence from an archaic Denisovan individual. Science 338: 222-226.
-
(2012)
Science
, vol.338
, pp. 222-226
-
-
Meyer, M.1
Kircher, M.2
Gansauge, M.T.3
Li, H.4
Racimo, F.5
-
29
-
-
79959536171
-
Induction and patterning of intramembranous bone
-
Franz-Odendaal TA, (2011) Induction and patterning of intramembranous bone. Front Biosci 16: 2734-2746.
-
(2011)
Front Biosci
, vol.16
, pp. 2734-2746
-
-
Franz-Odendaal, T.A.1
-
30
-
-
58749111473
-
A Runx2 threshold for the cleidocranial dysplasia phenotype
-
Lou Y, Javed A, Hussain S, Colby J, Frederick D, et al. (2009) A Runx2 threshold for the cleidocranial dysplasia phenotype. Hum Mol Genet 18: 556-558.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 556-558
-
-
Lou, Y.1
Javed, A.2
Hussain, S.3
Colby, J.4
Frederick, D.5
-
31
-
-
84860331458
-
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
-
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, et al. (2012) Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 44: 491-501.
-
(2012)
Nat Genet
, vol.44
, pp. 491-501
-
-
Estrada, K.1
Styrkarsdottir, U.2
Evangelou, E.3
Hsu, Y.H.4
Duncan, E.L.5
-
32
-
-
33144479730
-
Association of functionally different RUNX2 P2 promoter alleles with BMD
-
Doecke JD, Day CJ, Stephens AS, Carter SL, van Daal A, et al. (2006) Association of functionally different RUNX2 P2 promoter alleles with BMD. J Bone Miner Res 21: 265-273.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 265-273
-
-
Doecke, J.D.1
Day, C.J.2
Stephens, A.S.3
Carter, S.L.4
van Daal, A.5
-
33
-
-
34848816852
-
Promoter 2 -1025 T/C polymorphism in the RUNX2 gene is associated with femoral neck BMD in Spanish postmenopausal women
-
Bustamante M, Nogués X, Agueda L, Jurado S, Wesselius A, et al. (2007) Promoter 2-1025 T/C polymorphism in the RUNX2 gene is associated with femoral neck BMD in Spanish postmenopausal women. Calcif Tissue Int 81: 327-332.
-
(2007)
Calcif Tissue Int
, vol.81
, pp. 327-332
-
-
Bustamante, M.1
Nogués, X.2
Agueda, L.3
Jurado, S.4
Wesselius, A.5
-
34
-
-
78349276509
-
Common polymorphisms rather than rare genetic variants of the Runx2 gene are associated with femoral neck BMD in Spanish women
-
Pineda B, Hermenegildo C, Laporta P, Tarín JJ, Cano A, et al. (2010) Common polymorphisms rather than rare genetic variants of the Runx2 gene are associated with femoral neck BMD in Spanish women. J Bone Miner Metab 28: 696-705.
-
(2010)
J Bone Miner Metab
, vol.28
, pp. 696-705
-
-
Pineda, B.1
Hermenegildo, C.2
Laporta, P.3
Tarín, J.J.4
Cano, A.5
-
35
-
-
45149117995
-
Family-based association study of polymorphisms in the RUNX2 locus with hand bone length and hand BMD
-
Ermakov S, Malkin I, Keter M, Kobyliansky E, Livshits G, (2008) Family-based association study of polymorphisms in the RUNX2 locus with hand bone length and hand BMD. Ann Hum Genet 72: 510-518.
-
(2008)
Ann Hum Genet
, vol.72
, pp. 510-518
-
-
Ermakov, S.1
Malkin, I.2
Keter, M.3
Kobyliansky, E.4
Livshits, G.5
-
36
-
-
67349133555
-
Association of a RUNX2 promoter polymorphism with bone mineral density in postmenopausal Korean women
-
Lee HJ, Koh JM, Hwang JY, Choi KY, Lee SH, et al. (2009) Association of a RUNX2 promoter polymorphism with bone mineral density in postmenopausal Korean women. Calcif Tissue Int 84: 439-445.
-
(2009)
Calcif Tissue Int
, vol.84
, pp. 439-445
-
-
Lee, H.J.1
Koh, J.M.2
Hwang, J.Y.3
Choi, K.Y.4
Lee, S.H.5
-
37
-
-
31544483312
-
Variation in femoral length is associated with polymorphisms in RUNX2 gene
-
Ermakov S, Malkin I, Kobyliansky E, Livshits G, (2006) Variation in femoral length is associated with polymorphisms in RUNX2 gene. Bone 38: 199-205.
-
(2006)
Bone
, vol.38
, pp. 199-205
-
-
Ermakov, S.1
Malkin, I.2
Kobyliansky, E.3
Livshits, G.4
-
38
-
-
26244452990
-
Mutations and promoter SNPs in RUNX2, a transcriptional regulator of bone formation
-
Napierala D, Garcia-Rojas X, Sam K, Wakui K, Chen C, et al. (2005) Mutations and promoter SNPs in RUNX2, a transcriptional regulator of bone formation. Mol Genet Metab 86: 257-268.
-
(2005)
Mol Genet Metab
, vol.86
, pp. 257-268
-
-
Napierala, D.1
Garcia-Rojas, X.2
Sam, K.3
Wakui, K.4
Chen, C.5
-
39
-
-
2442500486
-
Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis
-
Xiao ZS, Hjelmeland AB, Quarles LD, (2004) Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis. J Biol Chem 79: 20307-20313.
-
(2004)
J Biol Chem
, vol.79
, pp. 20307-20313
-
-
Xiao, Z.S.1
Hjelmeland, A.B.2
Quarles, L.D.3
-
40
-
-
73949100416
-
Dose dependent effect of RUNX2 on bone development
-
Zhang S, Xiao Z, Luo J, He N, Mahlio J, et al. (2009) Dose dependent effect of RUNX2 on bone development. J Bone Miner Res 24: 1889-1904.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 1889-1904
-
-
Zhang, S.1
Xiao, Z.2
Luo, J.3
He, N.4
Mahlio, J.5
-
42
-
-
11144230088
-
Molecular origins of rapid and continuous morphological evolution
-
Fondon JW 3rd, Garner HR, (2004) Molecular origins of rapid and continuous morphological evolution. Proc Natl Acad Sci USA 101: 18058-18063.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 18058-18063
-
-
Fondon 3rd, J.W.1
Garner, H.R.2
-
43
-
-
35748963803
-
The correlated evolution of Runx2 tandem repeats, transcriptional activity, and facial length in carnivora
-
Sears KE, Goswami A, Flynn JJ, Niswander LA, (2007) The correlated evolution of Runx2 tandem repeats, transcriptional activity, and facial length in carnivora. Evol Dev 9: 555-565.
-
(2007)
Evol Dev
, vol.9
, pp. 555-565
-
-
Sears, K.E.1
Goswami, A.2
Flynn, J.J.3
Niswander, L.A.4
-
44
-
-
84862759216
-
RUNX2 tandem repeats and the evolution of facial length in placental mammals
-
Pointer MA, Kamilar JM, Warmuth V, Chester SGB, Delsuc F, et al. (2012) RUNX2 tandem repeats and the evolution of facial length in placental mammals. BMC Evol Biol 12: 103.
-
(2012)
BMC Evol Biol
, vol.12
, pp. 103
-
-
Pointer, M.A.1
Kamilar, J.M.2
Warmuth, V.3
Chester, S.G.B.4
Delsuc, F.5
|