Breast cancer personalized medicine: Challenges and opportunities

American Journal of Pathology

Volumn 183, Issue 4, 2013, Pages 1036-1037

  Coleman, William B ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BRCA1 PROTEIN; BRCA2 PROTEIN; PROTEIN P53;

BREAST CANCER; CANCER MORTALITY; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA METHYLATION; EDITORIAL; ENVIRONMENTAL EXPOSURE; EPIGENETICS; ETHNICITY; FAMILIAL CANCER; GENE EXPRESSION; GENE MUTATION; GENETIC PREDISPOSITION; GENOMICS; HISTONE MODIFICATION; HISTOPATHOLOGY; HUMAN; LIFESPAN; LONG TERM SURVIVAL; MOLECULAR BIOLOGY; MOLECULAR EVOLUTION; MOLECULAR PATHOLOGY; PATIENT CARE; PERSONALIZED MEDICINE; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; SYNDROME; TREATMENT RESPONSE;

BREAST NEOPLASMS; BREAST NEOPLASMS, MALE; EPIGENESIS, GENETIC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDIVIDUALIZED MEDICINE; MALE; RISK FACTORS;

EID: 84884582994     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.08.001     Document Type: Editorial

References (15)

1. R. Snyderman Personalized health care: from theory to practice Biotechnol J 7 2012 973 979
2. K. Polyak Breast cancer: origins and evolution J Clin Invest 117 2007 3155 3163
3. S.A. Gayther, P.D. Pharoah, and B.A. Ponder The genetics of inherited breast cancer J Mammary Gland Biol Neoplasia 3 1998 365 376
4. S. Sutcliffe, P.D. Pharoah, D.F. Easton, and B.A. Ponder Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer Int J Cancer 87 2000 110 117
5. B.A. Ponder, A. Antoniou, A. Dunning, D.F. Easton, and P.D. Pharoah Polygenic inherited predisposition to breast cancer Cold Spring Harb Symp Quant Biol 70 2005 35 41
6. J.L. Kelsey, and G.S. Berkowitz Breast cancer epidemiology Cancer Res 48 1988 5615 5623
7. S. Ogino, C.S. Fuchs, and E. Giovannucci How many molecular subtypes? Implications of the unique tumor principle in personalized medicine Expert Rev Mol Diagn 12 2012 621 628
8. R. Dienstmann, J. Rodon, J. Barretina, and J. Tabernero Genomic medicine frontier in human solid tumors: prospects and challenges J Clin Oncol 31 2013 1874 1884
9. M. Ghoussaini, P.D.P. Pharoah, and D.F. Easton Inherited genetic susceptibility to breast cancer: the beginning of the end or the end of the beginning Am J Pathol 183 2013 1038 1051
10. O.A. Stefansson, and M. Esteller Epigenetic modifications in breast cancer and their role in personalized medicine Am J Pathol 183 2013 1052 1063
11. O. Engebraaten, H.K. Vollan, H.G. Russnes, H. Gythfeldt, and A.L. Borresen-Dale Triple-negative breast cancer and the need for new therapeutic targets Am J Pathol 183 2013 1064 1074
12. F.B. De Abreu, W.A. Wells, and G.J. Tsongalis The emerging role of the molecular diagnostics laboratory in breast cancer personalized medicine Am J Pathol 183 2013 1075 1083
13. N. Marino, S. Woditschka, L.T. Reed, J. Nakayama, M. Mayer, M. Wetzel, and P.S. Steeg Breast cancer metastasis: issues for the personalization of its prevention and treatment Am J Pathol 183 2013 1084 1095
14. A. Mohamed, K. Krajewski, B. Cakar, and C.X. Ma Targeted therapy for breast cancer Am J Pathol 183 2013 1096 1112
15. A.G. Rivenbark, S.M. O'Connor, and W.B. Coleman Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine Am J Pathol 183 2013 1113 1124