Stereospecific asymmetric N-heterocyclic carbene (NHC)-catalyzed redox synthesis of trifluoromethyl dihydropyranones and mechanistic insights

Journal of Organic Chemistry

Volumn 78, Issue 18, 2013, Pages 9243-9257

  Davies, Alyn T ^a   Taylor, James E ^a   Douglas, James ^a   Collett, Christopher J ^a   Morrill, Louis C ^a   Fallan, Charlene ^a   Slawin, Alexandra M Z ^a   Churchill, Gwydion ^b   Smith, Andrew D ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIASTEREO-SELECTIVITY; DIHYDROPYRANONES; HETERO-DIELS-ALDER REACTIONS; MECHANISTIC STUDIES; N-HETEROCYCLIC CARBENES; REDOX SYNTHESIS; STEREOSPECIFIC; TRIFLUOROMETHYL;

CATALYSIS;

ORGANIC COMPOUNDS;

CARBENE; ISOTOPE; PYRAN DERIVATIVE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHIRALITY; DERIVATIZATION; DIELS ALDER REACTION; ENANTIOSELECTIVITY; MEASUREMENT; MOLECULAR DYNAMICS; OXIDATION REDUCTION REACTION; STEREOCHEMISTRY; STEREOSPECIFICITY; SYNTHESIS;

EID: 84884579203     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo401433q     Document Type: Article

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