Comparative tissue distribution profiles of five major bio-active components in normal and blood deficiency rats after oral administration of Danggui Buxue Decoction by UPLC-TQ/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 207-215

  Shi, Xuqin ^a   Tang, Yuping ^a   Zhu, Huaxu ^a   Li, Weixia ^a   Li, Zhenhao ^a   Li, Wei ^a   Duan, Jin ao ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Bleeding; Blood deficiency; Blood loss anemia; Danggui Buxue Decoction; Tissue distribution; UPLC TQ MS

Indexed keywords

ASTRAGALOSIDE IV; CAFFEIC ACID; CALYCOSIN 7 O BETA GLUCOSIDE; CARBOHYDRATE DERIVATIVE; CHINESE DRUG; CHLORAMPHENICOL; CLARITHROMYCIN; DANGGUI BUXUE; FERULIC ACID; ONONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING; DRUG DISTRIBUTION; FEMALE; HEART; KIDNEY; LIVER; LUNG; MALE; NONHUMAN; ORBIT; PRIORITY JOURNAL; RAT; SPLEEN; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION; TISSUE HOMOGENATE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BLEEDING; BLOOD DEFICIENCY; BLOOD LOSS ANEMIA; DANGGUI BUXUE DECOCTION; TISSUE DISTRIBUTION; UPLC-TQ/MS;

ADMINISTRATION, ORAL; ANEMIA; ANIMALS; CAFFEIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARIC ACIDS; DRUGS, CHINESE HERBAL; FEMALE; GLUCOSIDES; ISOFLAVONES; MALE; MASS SPECTROMETRY; MEDICINE, CHINESE TRADITIONAL; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SAPONINS; TISSUE DISTRIBUTION; TRITERPENES;

EID: 84884574727     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.08.043     Document Type: Article

References (27)

1. Moqhadam S.A., Faqhihi S., Amid R., Kadkhodazadeh M., Hosseini S.K. Comprehensive oral rehabilitation of a patient with aplastic anemia by periodontal and prosthesis treatments. Compend. Contin. Educ. Dent. 2012, 33:e62-e66.
2. Lyon A.W., Chin A.C., Slotsve G.A., Lyon M.E. Simulation of repetitive diagnostic blood loss and onset of iatrogenic anemia in critical care patients with a mathematical model. Comput. Biol. Med. 2013, 43:84-90.
3. Ravanbod M., Asadipooya K., Kalantarhormozi M., Nabipour I., Omrani G.R. Treatment of iron-deficiency anemia in patients with subclinical hypothyroidism. Am. J. Med. 2013, 126:420-424.
4. Barbosa M.C., Dos Santos T.E., De Souza G.F., De Assis L.C., Freitas M.V., Goncalves R.P. Impact of iron overload on interleukin-10 levels, biochemical parameters and oxidative stress in patients with sickle cell anemia. Rev. Bras. Hematol. Hemoter. 2013, 35:29-34.
5. Shi X.Q., Li W.X., Tang Y.P., Zhu H.X., Li W., Qian D.W., Duan J.A. Establishment and optimization of rat blood deficiency model by chronic bleeding. Chin. Pharmacol. Bull. 2013, 29:437441.
6. Li H., Wang S.W., Zhang B.L., Xie Y.H., Wang J.B., Yang Q., Cao W., Hu J., Duan L.R. Influence of co-administered Danshensu on pharmacokinetic fate and tissue distribution of paeonol in rats. Planta Med. 2012, 78:135-140.
7. Gao Q.T., Choi C.Y., Cheung W.H., Zhu T.T., Li J., Chu K.Y., Duan R., Cheung K.H., Jiang Z.Y., Dong X.B., Zhao K.J., Dong T.X., Tsim W.K. Danggui Buxue Tang-a Chinese herbal decoction activates the phosphorylations of extracellular signal-regulated kinase and estrogen receptor alpha in cultured MCF-7 cells. FEBS Lett. 2007, 581:233-240.
8. Shi X.Q., Shang E.X., Tang Y.P., Zhu H.X., Guo J.M., Huang M.Y., Li W.X., Duan J.A. Interaction of nourishing and tonifying blood effects of the combination of Angelicae sinensis Radix and Astragali Radix studied by response surface method. Acta Pharm. Sin. 2012, 47:1375-1383.
9. Dong T.X., Zhao K.J., Gao Q.T., Ji Z.N., Zhu T.T., Li J., Duan R., Cheung W.H., Tsim W.K. Chemical biological assessment of a Chinese herbal decoction containing Radix Astragali and Radix Angelicae Sinensis: determination of drug ratio in having optimized properties. J. Agric. Food Chem. 2006, 54:2767-2774.
10. Gao Q.T., Cheung K.H., Li J., Chu K.Y., Duan R., Cheung W.H., Zhao K.J., Dong T.X., Tsim W.K. A Chinese herbal decoction, danggui buxue tang, prepared from Ranix Astragali and Radix Angelicae Sinensis stimulates the immune responses. Planta Med. 2006, 72:1227-1231.
11. Zheng Y.Z., Choi C.Y., Guo J.Y., Bi W.C., Zhu Y., Du Y.Q., Zhang Z.X., Lau T.W., Dong T.X., Tsim W.K. The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: a synergistic action of an ancient herbal decoction Danggui Buxue Tang. J. Pharm. Biomed. Anal. 2012, 70:671-679.
12. Zhang W.D., Zhang C., Liu R.H., Li H.L., Zhang J.T., Mao C., Sara M., Chen C.L. Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs. Life Sci. 2006, 79:808-815.
13. Qian M., Shi L.F., Hu J.H. Distribution of ligustilide in mouse tissues after oral administration of the essential oils from Ligusticum chuanxiong hort. Pharm. Care Res. 2008, 8:130-132.
14. Wang N.N., Li X.H., Li Y., Jiang M.Y. Study on the tissue distribution 3-n-butylphthalide in rats by HPLC. Chin. Pharm. J. 2012, 47:1574-1577.
15. Tian Y., Yang Z.F., Li Y., Qiao Y., Yang J., Jia Y.Y., Wen A.D. Pharmacokinetic comparisons of hydroxysafflower yellow A in normal and blood stasis syndrome rats. J. Ethnopharmacol. 2010, 129:1-4.
16. Zhang X., Qi L.W., Yi L., Li P., Wen X.D., Yu Q.T. Screening and identification of potential bioactive components in a combined prescription of Danggui Buxue decoction using cell extraction coupled with high performance liquid chromatography. Biomed. Chromatogr. 2008, 22:157-163.
17. Wen X.D., Qi L.W., Chen J., Song Y., Yi L., Yang X.W., Li P. Analysis of interaction property of bioactive components in Danggui Buxue Decoction with protein by microdialysis coupled with HPLC-DAD-MS. J. Chromatogr. B 2007, 852:598-604.
18. Huang C.R., Wang G.J., Li H., Xie H.T., Sun J.G., Lv H., Lv T. Sensitive and selective liquid chromatography-electrospray ionisation spectrometry analysis of astragaloside IV in rat plasma. J. Pharm. Biomed. Anal. 2006, 40:788-793.
19. Wang Z.J., Wo S.K., Wang L., Lau C.B., Lee V.H., Chow M.S., Zuo Z. Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography-mass spectrometry. J. Pharm. Biomed. Anal. 2009, 50:232-244.
20. Rukkumani R., Aruna K., Varma P.S., Menon V.P. Hepatoprotective role of ferulic acid: a dose-dependent study. J. Med. Food 2004, 7:456-461.
21. Janbaz K.H., Saeed S.A., Gilani A.H. Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine 2004, 11:424-430.
22. Liu J., Hu X.G., Yang Q., Yu Z.L., Zhao Z.Z., Yi T., Chen H.B. Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari. J. Biomed. Biotechnol. 2010, article ID 479426, 12 pp.
23. Qi L., Liu C.Y., Wu W.Q., Gu Z.L., Guo C.Y. Protective effect of flavonoids from Astragalus complanatus on radiation induced damages in mice. Fitoterapia 2011, 82:383-392.
24. Liang G.L., Bi J.B., Huang H.Q., Zhang S., Hu C.Q. Metabolites and the pharmacokinetics of kobophenol A from Caragana sinica in rats. J. Ethnopharmacol. 2005, 101:324-329.
25. Wang S.L., Yu F.B., Jiang T.Y., Sun C.S., Wang T.Y., Zhang J.H. Design and synthesis of novel galactosylated polymers for liposomes as gene drug carriers targeting the hepatic asialoglycoprotein receptor. J. Drug Target. 2008, 16:233-242.
26. Huo C., Wang M., Ma Z.C., Zhang Q., Yan X.Z., Zhang B.L., Gao Y. NMR-spectroscopy-based metabonomic study on the mouse model of blood deficiency syndrome induced by radiation. Tianjin J. Tradit. Chin. Med. 2010, 27:233-235.
27. Li W.X., Guo J.M., Tang Y.P., Wang H., Huang M.Y., Qian D.W., Duan J.A. Pharmacokinetic comparison of ferulic acid in normal and blood deficiency rats after oral administration of Angelica sinensis, Ligusticum chuanxiong and their combination. Int. J. Mol. Sci. 2012, 13:3583-3597.