Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions-response

Clinical Cancer Research

Volumn 19, Issue 18, 2013, Pages 5255-

  Chene, Gautier ^a   Tchirkov, Andrei ^a   Penault Llorca, Frederique ^a  

^a UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TELOMERASE;

AGE DISTRIBUTION; DNA DAMAGE; DYSPLASIA; ENZYME REACTIVATION; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; LETTER; OVARY CANCER; OVARY DISEASE; PRIORITY JOURNAL; TELOMERE SHORTENING; TUBOOVARIAN PRENEOPLASTIC LESION; TUMOR SUPPRESSOR GENE; UTERINE TUBE CARCINOMA; UTERINE TUBE DISEASE;

FALLOPIAN TUBE NEOPLASMS; FEMALE; GENOMIC INSTABILITY; HUMANS; OVARIAN NEOPLASMS; PRECANCEROUS CONDITIONS; TELOMERE SHORTENING;

EID: 84884574483     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-1915     Document Type: Letter

References (4)

1. Chene G, Tchirkov A, Pierre-Eymard E, Daupla J, Raoelfils I, Cayre A, et al. Early telomere shortening and genomic instability in tuboovarian preneoplastic lesions. Clin Cancer Res 2013;19:2873-82.
2. Raynaud CM, Sabatier L, Philipot O, Olaussen KA, Soria JC. Telomere length, telomeric proteins and genomic instability during the multistep carcinogenic process. Crit Rev Oncol Hematol 2008;66:99-117.
3. Kuhn E, Meeker A, Wang TL, Sehdev AS, Kurman RJ, Shih IM. Shortened telomeres in serous tubal intraepithelial carcinoma: an early event in ovarian high-grade serous carcinogenesis. Am J Surg Pathol 2010;34:829-36.
4. Martinez-Delgado B, Yanowsky K, Inglada-Perez L, de la Hoya M, Caldes T, Vega A, et al. Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases. J Med Genet 2012;49:341-4.