Regulation of PTEN/Akt Pathway Enhances Cardiomyogenesis and Attenuates Adverse Left Ventricular Remodeling following Thymosin β4 Overexpressing Embryonic Stem Cell Transplantation in the Infarcted Heart

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Yan, Binbin ^a   Singla, Reetu D ^a   Abdelli, Latifa S ^a   Singal, Pawan K ^b   Singla, Dinender K ^a  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CASPASE 3; GELATINASE B; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN MEF2C; PROTEIN TXB6; THYMOSIN BETA4; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOMYOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EMBRYOID BODY; EMBRYONIC STEM CELL; EMBRYONIC STEM CELL TRANSPLANTATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; HEART DEVELOPMENT; HEART INFARCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; HEART VENTRICLE REMODELING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STEM CELL TRANSPLANTATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; FIBROSIS; HEART; MICE; MICE, INBRED C57BL; MUSCLE DEVELOPMENT; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; THYMOSIN; TRANSCRIPTION FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84884567160     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075580     Document Type: Article

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