Delayed progression of edema formation around a hematoma expressing high levels of VEGF and MMP-9 in a patient with traumatic brain injury: Case report

Neurologia Medico-Chirurgica

Volumn 53, Issue 9, 2013, Pages 609-612

  Hirose, Tomoya ^a   Matsumoto, Naoya ^a   Tasaki, Osamu ^b   Nakamura, Hajime ^a   Akagaki, Fuyuko ^a   Shimazu, Takeshi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Brain edema; Hematoma; Matrix metalloproteinase 9; Traumatic brain injury; Vascular endothelial growth factor

Indexed keywords

GELATINASE B; VASCULOTROPIN;

ADULT; ARTICLE; BRAIN CONTUSION; BRAIN EDEMA; BRAIN HEMATOMA; BRAIN INFECTION; CASE REPORT; CENTRIFUGATION; COMPUTER ASSISTED TOMOGRAPHY; CRANIOTOMY; DISEASE COURSE; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITAL ADMISSION; HUMAN; IMAGE ENHANCEMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PHAGOCYTE; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION; SUPERNATANT; TRAUMATIC BRAIN INJURY; WHITE MATTER LESION;

BRAIN EDEMA; BRAIN INJURIES; FEMALE; HEMATOMA; HUMANS; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84884565754     PISSN: 04708105     EISSN: 13498029     Source Type: Journal    
DOI: 10.2176/nmc.cr2012-0342     Document Type: Article

References (15)

1. Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, Fini ME, Lo EH: Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 21: 7724-7732, 2001
2. Coenjaerts FE, van der Flier M, Mwinzi PN, Brouwer AE, Scharringa J, Chaka WS, Aarts M, Rajanuwong A, van de Vijver DA, Harrison TS, Hoepelman AI: Intrathecal production and secretion of vascular endothelial growth factor during cryptococcal meningitis. J Infect Dis 190: 1310-1317, 2004
3. Donkin JJ, Vink R: Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments. Curr Opin Neurol 23: 293-299, 2010
4. Gasche Y, Fujimura M, Morita-Fujimura Y, Copin JC, Kawase M, Massengale J, Chan PH: Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction. J Cereb Blood Flow Metab 19: 1020-1028, 1999
5. Grossetete M, Phelps J, Arko L, Yonas H, Rosenberg GA: Elevation of matrix metalloproteinases 3 and 9 in cerebrospinal fluid and blood in patients with severe traumatic brain injury. Neurosurgery 65: 702-708, 2009
6. Hayashi T, Kaneko Y, Yu S, Bae E, Stahl CE, Kawase T, van Loveren H, Sanberg PR, Borlongan CV: Quantitative analyses of matrix metalloproteinase activity after traumatic brain injury in adult rats. Brain Res 1280: 172-177, 2009
7. Hohenstein A, Erber R, Schilling L, Weigel R: Increased mRNA expression of VEG F within the hematoma and imbalance of angiopoietin-1 and-2 mRNA within the neo membranes of chronic subdural hematoma. J Neurotrauma 22: 518-528, 2005
8. La Fleur M, Underwood JL, Rappolee DA, Werb Z: Basement membrane and repair of injury to peripheral nerve: defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1. J Exp Med 184: 2311-2326, 1996
9. Lee S, Chen TT, Barber CL, Jordan MC, Murdock J, Desai S, Ferrara N, Nagy A, Roos KP, Iruela-Arispe, ML: Autocrine VEGF signaling is required for vascular homeostasis. Cell 130: 691-703, 2007
10. Marmarou A: Pathophysiology of traumatic brain edema: current concepts. Acta Neurochir Suppl 86: 7-10, 2003
11. Stocchetti N, Colombo A, Ortolano F, Videtta W, Marchesi R, Longhi L, Zanier ER: Time course of intracranial hypertension after traumatic brain injury. J Neurotrauma 24: 1339-1346, 2007
12. Suzuki R, Fukai N, Nagashijma G, Asai JI, Itokawa H, Nagai M, Suzuki T, Fujimoto T: Very early expression of vascular endothelial growth factor in brain oedema tissue associated with brain contusion. Acta Neurochir Suppl 86: 277-279, 2003
13. Suzuki R, Tomita H, Ito U, Nagashima G, Miyo T, Fujimoto T: Late expression of vascular endotherial growth factor in the reactive astrocytes in experimental intracerebral hemorrhage in cats. Cereb Blood Flow Metab 17: S416, 1997
14. Unterberg AW, Stover J, Kress B, Kiening KL: Edema and brain trauma. Neuroscience 129: 1021-1029, 2004
15. Vajtr D, Benada O, Kukacka J, Prusa R, Houstava L, Toupalik P, Kizek R: Correlation of ultrastructural changes of endothelial cells and astrocytes occurring during blood brain barrier damage after traumatic brain injury with biochemical markers of BBB leakage and inflammatory response. Physiol Res 58: 263-268, 2009