Denture polymers with antimicrobial properties: A review of the development and current status of anionic poly(methyl methacrylate) polymers

Future Medicinal Chemistry

Volumn 5, Issue 14, 2013, Pages 1635-1645

  Raj, Periathamby Antony ^a   Dentino, Andrew R ^b  

^a Division of Research and Development   (United States)

^b MARQUETTE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; CARBOXYLIC ACID; CHLORHEXIDINE GLUCONATE; CISPLATIN; HISTATIN 5; MICONAZOLE; PHOSPHATE; POLY(METHYL METHACRYLATE); POLYMER;

ANTIMICROBIAL ACTIVITY; BACTERIAL COLONIZATION; BIOFILM; CANDIDA ALBICANS; CHEMICAL MODIFICATION; DENTAL PELLICLE; DENTURE; HUMAN; INFECTION; POLYMERIZATION; PRIORITY JOURNAL; REVIEW; SAFETY; STOMATITIS; SURFACE PROPERTY; TOOTH PLAQUE;

ANIONS; ANTI-INFECTIVE AGENTS; DENTAL MATERIALS; DENTURES; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; POLYMETHYL METHACRYLATE;

EID: 84884565006     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.13.145     Document Type: Review

References (78)

1. Cökeliler D, Erkut S, Zemek J, Biederman H, Mutlu M. Modified implant surfaces show different biofilm compositions under in vivo conditions. Dent. Mater. 20(8), 817-826 (2009).
2. Busscher HJ, Rinastiti M, Siswomihardjo W, van der Mei HC. Energy transfer, volumetric expansion, and removal of oral biofilms by non-contact brushing. Eur. J. Oral Sci. 26(13), 11113-11117 (2010).
3. National Institute of Dental and craniofacial Research, NIH. Oral Health in America: A Report of the Surgeon General-Executive Summary. US Department of Health and Human Services, Rockville, MD, USA (2005).
4. The WHO. The World Oral Health Report. The WHO, Geneva, Switzerland (2003).
5. European Commission. Oral Health Report: A report of the European Commission special eurobarometer 329. TNS Opinion and Social, Brussels, Belgium (2010).
6. O'Brain WJ. Dental Materials: Properties and Selection. Quintessence Publishing Co., Inc., IL, USA, 157-176 (1989).
7. van Noort R. Introduction to Dental Materials. Times Mirror International Publishers Ltd, London, UK, 183-191 (1994).
8. Ferracane JL. Materials in Dentistry. JB Lippincott Company, PA, USA, 251-278 (1995).
9. Gocke R, Gerath F, von Schwanewede H. Quantitative determination of salivary components in the pellicle on PMMA denture base material. Clin. Oral Invest. 6(4), 227-235 (2002).
10. Samaranayake LP, Leung WK, Jin L. Oral Mucosal Fungal Infection. Periodontol. 2000 49, 29-59 (2009).
11. Webb BC, Thomas CJ, Willcox MD, Harty DW, Knox KW. Candida-associated denture stomatitis. Aetiology and management: A review. Part 3. Treatment of oral candidosis. Aust. Dent. J. 43(4), 244-249 (1998).
12. Busscher HJ, Rinastiti M, Siswomihardjo W, van der Mei HC. Biofilm formation on dental restorative and implant materials. J. Dent. Res. 89(7), 657-665 (2010).
13. Flemming T, Beikler T. Control of oral biofilms. Priodontol. 2000 55, 9-15 (2011).
14. Lovell LG, Newman SM, Bowman CN. The effect of light intensity, temperature, and comonomer composition on the polymerization behavior of dimethacrylate dental resins. J. Dent. Res. 78(8), 1469-1476 (1999).
15. Kanie T, Arikawaa H, Fujii K, Ban S. Light-curing reinforcement for denture base resin using a glass fiber cloth pre-impregnated with various urethane oligomers. Dent. Mater. J. 23 (3), 291-296 (2004).
16. Hong G, Murata H, Hamada T. Relationship between plasticizer content and tensile bond strength of soft denture liners to a denture base resin. Dent. Mater. J. 23(2), 94-99 (2004).
17. Chandra J, Patel JD, Li J et al. Modification of surface properties of biomaterials influences the ability of Candida albicans to form biofilms. Appl. Environ. Microbiol. 71(12), 8795-8801 (2005).
18. Edgerton M, Raj PA, Levine MJ. Surface-modified poly methyl methacrylate enhances adsorption and retains anticandidal activities of salivary histatin 5. J. Biomed. Mat. Res. 29(10), 1277-1286 (1995).
19. Raj PA, Soni S-D, Levine MJ. Membrane-induced helical conformation of an active candidacidal fragment of salivary histatins. J. Biol. Chem. 269(13), 9610-9619 (1994).
20. Edgerton M, Koshlukova SE, Lo TE, Chrzan BG, Straubinger RM, Raj PA. Candidacidal activity of histatins: Identification of anhistatin 5 binding protein on Candida albicans. J. Biol. Chem. 273(32), 20438-20447 (1998).
21. Raj PA, Dentino AR. Current status of defensins and their role in innate and adaptive immunity. FEMS Microbiol. Lett. 206(1), 9-18 (2002).
22. Raj PA, Dentino AR. New phosphatedpoly(methyl methacrylate) polymers for the prevention of denture-induced microbial infection: An in vitro study. Clin. Cosmet. Invest. Dent. 3, 25-32 (2011).
23. Edgerton M, Levine MJ. Characterization of acquired denture pellicle from healthy and stomatitis patients. J. Prosthet. Dent. 68(4), 683-691 (1992).
24. Edgerton M, Scannapieco FA, Reddy MS, Levine MJ. Human submandibular-sublingual saliva promotes adhesion of Candida albicans to polymethylmethacrylate. Infect. Immun. 61(6), 2644-2652 (1993).
25. Hoffman MP, Haidaris CG. Analysis of Candida albicans adhesion to salivary mucins. Infect. Immun. 61(5), 1940-1949 (1993).
26. Siqueira WL, Margolis HC, Helmerhorst EJ, Mendes FM, Oppenheim FG. Evidence of intact histatins in the in vivo acquired enamel pellicle. J. Dent. Res. 89(6), 626-630 (2010).
27. Siqueira WL, Custodio W, McDonald EE. New insights into the composition and functions of the acquired enamel pellicle. J. Dent. Res. 91(12), 1110-1118 (2012).
28. Raj PA, Johnsson M, Levine MJ, Nancollas GH. Salivary statherin. Dependence on sequence, charge, hydrogen bonding potency, and helical conformation for adsorption to hydroxyapatite and inhibition of mineralization. J. Biol. Chem. 267(9), 5968-5976 (1992).
29. Verran J. Denture plaque, denture stomatitis and the adhesion of Candida albicans to inert materials. In: Oral Biofilms and Plaque Control. Busscher HJ, Evans LV (Eds). Harwood Academic Publishers, The Netherlands, 175-191 (1998).
30. Morris IJ, Wade WG, Aldred MJ, Walker DM. The early bacterial colonization of acrylic plates in man. J. Oral Rehabil. 14(1), 13-21 (1987).
31. Walter B, Frank RM, Steuer P. Ultrastructual development of dated plaque in case of denture stomatitis, J. de Biologie Buccale 14, 115-124 (1986).
32. Mei L, Busscher HJ, van der Mei HC, Ren Y. Influence of surface roughness on streptococcal adhesion forces to composite resins. Dent. Mater. 27(8), 770-778 (2011).
33. Fouche MH, Slabbert JCG, Coogan M. Microorganisms isolated from patients with denture stomatitis. J. Dent. Assoc. S. Afr. 41, 313-316 (1986).
34. Eliason L, Dahlen G, Heyden G, Moller A. The predominant microflora of the palatal mucosa in an elderly island population. Acta Odontol. Scand. 50, 163-169 (1992).
35. Chopde N, Jawale B, Pharande A et al. Microbial colonization and their relation with potential cofactors in patients with denture stomatitis. J. Contemp. Dent. Pract. 13(4), 456-459 (2012).
36. Chandra J, Mukerjee PK, Leidich SD et al. Antifungal resistance of candidal biofilms formed on denture acrylic in vitro. J. Dent. Res. 80(3), 903-908 (2001).
37. Budtz-Jorgensen E. Oral mucusal lesions associated with wearing of removable dentures. J. Oral Pathol. 10(2), 65-80 (1981).
38. Lombardi T, Budtz-Jörgensen E. Treatment of denture-induced stomatitis: A review. Eur. J. Prosthodont. Restor. Dent. 2(1), 17-22 (1993).
39. Reichart PA. Oral mucosal lesions in a representative cross-sectional study of aging Germans. Community Dent. Oral Epidemiol. 28(5), 390-398 (2000).
40. Wilson J. The aetiology, diagnosis and management of denture stomatitis. Br. Dent. J. 185, 380-384 (1998).
41. Odds FC. Candida and Candidosis. WB Saunders, PA, USA (1988).
42. Redding S, Bhatt B, Rawls HR et al. Inhibition of Candida albicans biofilm formation on denture material. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 107(5), 669-672 (2009).
43. Iacopino AM, Wathen WF. Oral candidal infection and denture stomatitis: A comprehensive review. J. Am. Dent. Assoc. 123(3), 46-51 (1992).
44. Ramage G, Tomsett K, Wickes BL, Lopez-Ribot JL, Redding SW. Denture stomatitis: A role for Candida biofilms. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodont. 98(1), 53-59 (2004).
45. Chandra J, Mukherjee PK, Leidich SD et al. Antifungal resistance of candidal biofilms formed on denture acrylic in vitro. J. Dent. Res. 80(3), 903-908 (2001).
46. Li L, Finnegan S, Kim Y et al. In vitro study of biofilm formation and effectiveness of antimicrobial treatment on various dental material surfaces. Mol. Oral Microbial. 25, 384-390 (2010).
47. Gendreau L, Loewy ZG. Epidemiology and etiology of denture stomatitis. J. Prosthodont. 20(4), 251-260 (2011).
48. Radford DR, Sweet SP, Challacombe SJ, Walter JD. Adherence of Candida albicans to denture-base materials with different surface finishes. J. Dent. 26(7), 577-583 (1998).
49. Uyen HM, van der Mei HC, Weerkamp AH, Busscher HJ. Zeta potential and the adhesion of oral streptococci to polymethylmethacrylate. Biomater. Artif. Cells Artif. Organs 17(4), 385-391 (1989).
50. Park SE, Periathamby AR, Loza JC. Effect of surface-charged poly(methyl methacrylate) on the adhesion of Candida albicans. J. Prosthodont. 12(4), 249-254 (2003).
51. Pereira-Cenci T, Del BelCury AA, Crielaard W, Ten Cate JM. Development of Candida-associated denture stomatitis: New insights. J. Appl. Oral Sci. 16(2), 86-94 (2008).
52. Al-Dwairi ZN, Al-Quran FA, Al-Omari OY. The effect of antifungal agents on surface properties of poly(methyl methacrylate) and its relation to adherence of Candida albicans. J. Prosthodont. Res. 56(4), 272-280 (2012).
53. Park SE, Blissett R, Susarla SM, Weber H-P. Candida albicans adherence to surface-modified denture resin surfaces. J. Prosthodont. 17, 365-369 (2008).
54. Raj PA, Venkataraman G. New and novel denture-base polymers resistant to microbial infection. J. Dent. Res. 80, 51 (2001).
55. Odian G. Principles of Polymerization. John Wiley and sons, Inc., NJ, USA, 199-369 (2004).
56. Cao Z, Sun X, Yeh CK. Rechargeable infection-responsive antifungal denture material. J. Dent. Res. 89(12), 1517-1521 (2010).
57. Phoenix RD. Denture base resins: Technical considerations and processing techniques. In: Phillip's Science of Dental Materials. Anusavice KJ (Ed.). WB. Saunders Company, PA, USA 237-271 (1996).
58. Yan X, Gemeinhart RA. Cisplatin delivery from poly(acrylic acid-co-methyl methacrylate) microparticles. J. Control. Release 106(1-2), 198-208 (2005).
59. Moura JS, da Silva WJ, Pereira T et al. Influence of acrylic resin polymerization methods and saliva on the adherence of four Candida species. J. Prosthet. Dent. 96(3), 205-211 (2006).
60. Park SE, Chao M, Raj PA. Mechanical properties of surface-charged poly(methyl methacrylate) as denture resins. Int. J. Dent. 2009, Article ID 841431 (2009).
61. Ladizesky NH, Ho CF, Chow TW. Reinforcement of complete denture bases with continuous high performance polyethylene fibers. J. Prosthet. Dent. 68(6), 934-939 (1992).
62. Vallittu PK, Ekstrand K. A review of fiber-reinforced denture base resins. J. Prosthodont. 5(4), 270-276 (1996).
63. Jagger DC, Harrison A, Jandt KD. The reinforcement of dentures. J. Oral Rehabil. 26(3), 185-194 (1999).
64. Cökeliler D, Erkut S, Zemek J, Biederman H, Mutlu M. Modification of glass fibers to improve reinforcement: A plasma polymerization technique. Dent. Mater. 23(3), 335-342 (2007).
65. Scannapieco FA, Levine MJ. Saliva and dental pellicle. In: Contemporary Periodontics. Genco, RJ, Goldman HM, Cohen DW (Eds). Mosby Company, St. Louis, MO, USA 117-125 (1990).
66. Dhir G, Berzins DW, Dhuru VB, Periathamby AR, Dentino AR. Physical properties of denture base resins potentially resistant to Candida adhesion. J. Prosthodont. 16(6), 465-472 (2007).
67. Puri G, Berzins DW, Dhuru VB et al. Effect of phosphate group addition on the properties of denture base resins. J. Prosthet. Dent. 100(4), 302-308 (2008).
68. Flemming HC, Wingender J. The biofilm matrix. Nat. Rev. Microbiol. 8(9), 623-633 (2010).
69. O'Brien-Simpson NM, Dashper SG, Reynolds EC. Histatin 5 is a substrate and not an inhibitor of the Arg- and Lys-specific proteinases of Porphyromonas gingivalis. Biochem. Biophys. Res. Commun. 250(2), 474-478 (1998).
70. Helmerhorst EJ, Sun X, Salih E, Oppenheim FG. Identification of Lys-Pro-Gln as a novel cleavage site specificity of saliva-associated proteases. J. Biol. Chem. 283(29), 19957-19966 (2008).
71. Raj PA, Edgerton M, Levine MJ. Salivary histatin 5: Dependence of sequence, chain length, and helical conformation for candidacidal activity. J. Biol. Chem. 265(7), 3898-3905 (1990).
72. Rothstein DM, Spacciapoli P, Tran LT, Xu T et al. Anticandida activity is retained in P-113, a 12-amino-acid fragment of histatin 5. Arch. Oral Biol. 47(11), 749-756 (2001).
73. Antonyraj KJ, Karunakaran T, Raj PA. Bactericidal activity and poly-l-proline II conformation of the tandem repeat sequence of human salivary mucin glycoprotein (MG2). Arch Biochem. Biophys. 356(2), 197-206 (1998).
74. Dentino AR, Lee D, Wen G et al. Inhibition of Candida albicans biofilms on antimicrobial loaded phosphatedpoly(methyl methacrylate). Presented at: IADR General Session. Barcelona, Spain, 14-17 July 2010.
75. Lin DM, Kalachandra S, Valiyaparambil J, Offenbacher S. A polymeric device for delivery of anti-microbial and anti-fungal drugs in the oral environment: Effect of temperature and medium on the rate of drug release. Dent. Mater. 9(7), 589-596 (2003).
76. Abe Y, Ishii M, Takeuchi M, Tanaka S, Akagawa Y. Effect of saliva on an antimicrobial tissue conditioner containing silver-zeolite. J. Oral Rehabil. 31, 568-573 (2004).
77. Yoshinari M, Kato T, Matsuzaka K et al. Adsorption behavior of antimicrobial peptide histatin 5 on PMMA. J. Biomed. Mater. Res. B Appl. Biomater. 77(1), 47-54 (2006).
78. Rawls HR. Dental polymers. In: Phillips' Science of Dental Materials. Anusavice KJ (Ed.). WB Saunders Co., MO, USA, 145-146 (2003).