메뉴 건너뛰기




Volumn 4 AUG, Issue , 2013, Pages

Eat to reproduce: A key role for the insulin signaling pathway in adult insects

Author keywords

Female insect reproduction; insulin signaling pathway; Lipophilic hormones; Neuropeptides; Nutritional status

Indexed keywords

ECDYSTEROID; INSULIN; JUVENILE HORMONE;

EID: 84884555800     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00202     Document Type: Review
Times cited : (123)

References (196)
  • 1
    • 0031913246 scopus 로고    scopus 로고
    • Mechanism of activation and function of protein kinase B
    • Alessi, D. R., and Cohen, P. (1998) Mechanism of activation and function of protein kinase B. Curr. Opin. Genet. Dev. 8, 55-62.
    • (1998) Curr. Opin. Genet. Dev , vol.8 , pp. 55-62
    • Alessi, D.R.1    Cohen, P.2
  • 2
    • 78651265049 scopus 로고    scopus 로고
    • Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor
    • Alic, N., Hoddinott, M. P., Vinti, G., and Partridge, L. (2011) Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. Aging Cell 10, 137-147.
    • (2011) Aging Cell , vol.10 , pp. 137-147
    • Alic, N.1    Hoddinott, M.P.2    Vinti, G.3    Partridge, L.4
  • 3
    • 76849098343 scopus 로고    scopus 로고
    • Insect fat body: energy, metabolism, and regulation
    • Arrese, E. L., and Soulages, J. L. (2010) Insect fat body: energy, metabolism, and regulation. Annu. Rev. Entomol. 55, 207-225.
    • (2010) Annu. Rev. Entomol , vol.55 , pp. 207-225
    • Arrese, E.L.1    Soulages, J.L.2
  • 4
    • 77955455562 scopus 로고    scopus 로고
    • Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae
    • Arsic, D., and Guerin, P. M. (2008) Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae. J. Insect Physiol. 54, 1226-1235.
    • (2008) J. Insect Physiol , vol.54 , pp. 1226-1235
    • Arsic, D.1    Guerin, P.M.2
  • 5
    • 79961042330 scopus 로고    scopus 로고
    • Identification of novel bombyxin genes from the genome of the silkmoth Bombyx mori and analysis of their expression
    • Aslam, A. F., Kiya, T., Mita, K., and Iwami, M. (2011) Identification of novel bombyxin genes from the genome of the silkmoth Bombyx mori and analysis of their expression. Zoolog. Sci. 28, 609-616.
    • (2011) Zoolog. Sci , vol.28 , pp. 609-616
    • Aslam, A.F.1    Kiya, T.2    Mita, K.3    Iwami, M.4
  • 8
    • 84879857522 scopus 로고    scopus 로고
    • The IGFBP7 homolog Imp-L2 promotes insulin signaling in distinct neurons of the Drosophila brain
    • Bader, R., Sarraf-Zadeh, L., Peters, M., Moderau, N., Stocker, H., Kohler, K., et al. (2013) The IGFBP7 homolog Imp-L2 promotes insulin signaling in distinct neurons of the Drosophila brain. J. Cell Sci. 126(Pt 12), 2571-2576.
    • (2013) J. Cell Sci. , vol.126 , Issue.PART 12 , pp. 2571-2576
    • Bader, R.1    Sarraf-Zadeh, L.2    Peters, M.3    Moderau, N.4    Stocker, H.5    Kohler, K.6
  • 9
    • 42549146527 scopus 로고    scopus 로고
    • Purification and characterization of an insulin-related peptide in the desert locust, Schistocerca gregaria: immunolocalization, cDNA cloning, transcript profiling and interaction with neuroparsin
    • Badisco, L., Claeys, I., Van Hiel, M. B., Clynen, E., Huybrechts, J., Vandersmissen, T., et al. (2008) Purification and characterization of an insulin-related peptide in the desert locust, Schistocerca gregaria: immunolocalization, cDNA cloning, transcript profiling and interaction with neuroparsin. J. Mol. Endocrinol. 40, 137-150.
    • (2008) J. Mol. Endocrinol. , vol.40 , pp. 137-150
    • Badisco, L.1    Claeys, I.2    Van Hiel, M.B.3    Clynen, E.4    Huybrechts, J.5    Vandersmissen, T.6
  • 11
    • 79951511873 scopus 로고    scopus 로고
    • RNA interference of insulin-related peptide and neuroparsins affects vitellogenesis in the desert locust Schistocerca gregaria
    • Badisco, L., Marchal, E., Van Wielendaele, P., Verlinden, H., Vleugels, R., and Vanden Broeck, J. (2011) RNA interference of insulin-related peptide and neuroparsins affects vitellogenesis in the desert locust Schistocerca gregaria. Peptides 32, 573-580.
    • (2011) Peptides , vol.32 , pp. 573-580
    • Badisco, L.1    Marchal, E.2    Van Wielendaele, P.3    Verlinden, H.4    Vleugels, R.5    Vanden Broeck, J.6
  • 12
    • 84869209803 scopus 로고    scopus 로고
    • Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain
    • Bai, H., Kang, P., and Tatar, M. (2012) Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain. Aging Cell 11, 978-985.
    • (2012) Aging Cell , vol.11 , pp. 978-985
    • Bai, H.1    Kang, P.2    Tatar, M.3
  • 13
    • 84863318595 scopus 로고    scopus 로고
    • dSir2 deficiency in the fatbody, but not muscles, affects systemic insulin signaling, fat mobilization and starvation survival in flies
    • Banerjee, K. K., Ayyub, C., Sengupta, S., and Kolthur-Seetharam, U. (2012) dSir2 deficiency in the fatbody, but not muscles, affects systemic insulin signaling, fat mobilization and starvation survival in flies. Aging 4, 206-223.
    • (2012) Aging , vol.4 , pp. 206-223
    • Banerjee, K.K.1    Ayyub, C.2    Sengupta, S.3    Kolthur-Seetharam, U.4
  • 14
    • 84871875788 scopus 로고    scopus 로고
    • Fat body dSir2 regulates muscle mitochondrial physiology and energy homeostasis nonautonomously and mimics the autonomous functions of dSir2 in muscles
    • Banerjee, K. K., Ayyub, C., Sengupta, S., and Kolthur-Seetharam, U. (2013) Fat body dSir2 regulates muscle mitochondrial physiology and energy homeostasis nonautonomously and mimics the autonomous functions of dSir2 in muscles. Mol. Cell Biol. 33, 252-264.
    • (2013) Mol. Cell Biol , vol.33 , pp. 252-264
    • Banerjee, K.K.1    Ayyub, C.2    Sengupta, S.3    Kolthur-Seetharam, U.4
  • 15
    • 84877157614 scopus 로고    scopus 로고
    • Juvenile hormone and insulin suppress lipolysis between periods of lactation during tsetse fly pregnancy
    • Baumann, A. A., Benoit, J. B., Michalkova, V., Mireji, P., Attardo, G. M., Moulton, J. K., et al. (2013) Juvenile hormone and insulin suppress lipolysis between periods of lactation during tsetse fly pregnancy. Mol. Cell Endocrinol. 372, 30-41.
    • (2013) Mol. Cell Endocrinol , vol.372 , pp. 30-41
    • Baumann, A.A.1    Benoit, J.B.2    Michalkova, V.3    Mireji, P.4    Attardo, G.M.5    Moulton, J.K.6
  • 16
    • 29244461456 scopus 로고    scopus 로고
    • Disruption of insulin pathways alters trehalose level and abolishes sexual dimorphism in locomotor activity in Drosophila
    • Belgacem, Y. H., and Martin, J. R. (2006) Disruption of insulin pathways alters trehalose level and abolishes sexual dimorphism in locomotor activity in Drosophila. J. Neurobiol. 66, 19-32.
    • (2006) J. Neurobiol , vol.66 , pp. 19-32
    • Belgacem, Y.H.1    Martin, J.R.2
  • 17
    • 83155172619 scopus 로고    scopus 로고
    • Regulation of insulin-producing cells in the adult Drosophila brain via the tachykinin peptide receptor DTKR
    • Birse, R. T., Soderberg, J. A., Luo, J., Winther, A. M., and Nassel, D. R. (2011) Regulation of insulin-producing cells in the adult Drosophila brain via the tachykinin peptide receptor DTKR. J. Exp. Biol. 214, 4201-4208.
    • (2011) J. Exp. Biol , vol.214 , pp. 4201-4208
    • Birse, R.T.1    Soderberg, J.A.2    Luo, J.3    Winther, A.M.4    Nassel, D.R.5
  • 18
    • 0027233448 scopus 로고
    • Signal transduction via the MAP kinases: proceed at your own RSK
    • U.S.A.
    • Blenis, J. (1993) Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. U.S.A. 90, 5889-5892.
    • (1993) Proc. Natl. Acad. Sci , vol.90 , pp. 5889-5892
    • Blenis, J.1
  • 19
    • 78149267283 scopus 로고    scopus 로고
    • From insulin and insulin-like activity to the insulin superfamily of growth-promoting peptides: a 20th-century odyssey
    • Blumenthal, S. (2010) From insulin and insulin-like activity to the insulin superfamily of growth-promoting peptides: a 20th-century odyssey. Perspect. Biol. Med. 53, 491-508.
    • (2010) Perspect. Biol. Med , vol.53 , pp. 491-508
    • Blumenthal, S.1
  • 20
    • 0033603208 scopus 로고    scopus 로고
    • Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4
    • Bohni, R., Riesgo-Escovar, J., Oldham, S., Brogiolo, W., Stocker, H., Andruss, B. F., et al. (1999) Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell 97, 865-875.
    • (1999) Cell , vol.97 , pp. 865-875
    • Bohni, R.1    Riesgo-Escovar, J.2    Oldham, S.3    Brogiolo, W.4    Stocker, H.5    Andruss, B.F.6
  • 21
    • 0001250763 scopus 로고
    • The roles of juvenile hormone, ecdysone and the ovary in the control of Drosophila vitellogenesis
    • Bownes, M. (1989) The roles of juvenile hormone, ecdysone and the ovary in the control of Drosophila vitellogenesis. J. Insect Physiol. 35, 409-413.
    • (1989) J. Insect Physiol , vol.35 , pp. 409-413
    • Bownes, M.1
  • 22
    • 44449157170 scopus 로고    scopus 로고
    • An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti
    • U.S.A.
    • Brown, M. R., Clark, K. D., Gulia, M., Zhao, Z., Garczynski, S. F., Crim, J. W., et al. (2008) An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti. Proc. Natl. Acad. Sci. U.S.A. 105, 5716-5721.
    • (2008) Proc. Natl. Acad. Sci , vol.105 , pp. 5716-5721
    • Brown, M.R.1    Clark, K.D.2    Gulia, M.3    Zhao, Z.4    Garczynski, S.F.5    Crim, J.W.6
  • 24
    • 60549107098 scopus 로고    scopus 로고
    • Gonadal ecdysteroidogenesis in arthropoda: occurrence and regulation
    • Brown, M. R., Sieglaff, D. H., and Rees, H. H. (2009) Gonadal ecdysteroidogenesis in arthropoda: occurrence and regulation. Annu. Rev. Entomol. 54, 105-125.
    • (2009) Annu. Rev. Entomol , vol.54 , pp. 105-125
    • Brown, M.R.1    Sieglaff, D.H.2    Rees, H.H.3
  • 25
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., et al. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96, 857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3    Lin, M.Z.4    Juo, P.5    Hu, L.S.6
  • 26
    • 81255128898 scopus 로고    scopus 로고
    • Programmed autophagy in the fat body of Aedes aegypti is required to maintain egg maturation cycles
    • Bryant, B., and Raikhel, A. S. (2011) Programmed autophagy in the fat body of Aedes aegypti is required to maintain egg maturation cycles. PLoS ONE 6:e25502.
    • (2011) PLoS ONE , vol.6
    • Bryant, B.1    Raikhel, A.S.2
  • 27
    • 0004110219 scopus 로고
    • Previtellogenic Growth, and Evolution. London: Chapman and Hall
    • Büning, J. (1994) The Insect Ovary: Ultrastructure, Previtellogenic Growth, and Evolution. London: Chapman and Hall.
    • (1994) The Insect Ovary: Ultrastructure
    • Büning, J.1
  • 28
    • 27544504430 scopus 로고    scopus 로고
    • Alternate metabolism during the dauer stage of the nematode Caenorhabditis elegans
    • Burnell, A. M., Houthoofd, K., O'Hanlon, K., and Vanfleteren, J. R. (2005) Alternate metabolism during the dauer stage of the nematode Caenorhabditis elegans. Exp. Gerontol. 40, 850-856.
    • (2005) Exp. Gerontol , vol.40 , pp. 850-856
    • Burnell, A.M.1    Houthoofd, K.2    O'Hanlon, K.3    Vanfleteren, J.R.4
  • 29
    • 0030060198 scopus 로고    scopus 로고
    • The Drosophila insulin receptor is required for normal growth
    • Chen, C., Jack, J., and Garofalo, R. S. (1996) The Drosophila insulin receptor is required for normal growth. Endocrinology 137, 846-856.
    • (1996) Endocrinology , vol.137 , pp. 846-856
    • Chen, C.1    Jack, J.2    Garofalo, R.S.3
  • 30
    • 1942440368 scopus 로고    scopus 로고
    • cDNA cloning and transcriptional regulation of the vitellogenin receptor from the imported fire ant, Solenopsis invicta Buren (Hymenoptera: Formicidae) Insect Mol
    • Chen, M. E., Lewis, D. K., Keeley, L. L., and Pietrantonio, P. V. (2004) cDNA cloning and transcriptional regulation of the vitellogenin receptor from the imported fire ant, Solenopsis invicta Buren (Hymenoptera: Formicidae) Insect Mol. Biol. 13, 195-204.
    • (2004) Biol , vol.13 , pp. 195-204
    • Chen, M.E.1    Lewis, D.K.2    Keeley, L.L.3    Pietrantonio, P.V.4
  • 31
    • 0036129495 scopus 로고    scopus 로고
    • Insulin-related peptides and their conserved signal transduction pathway
    • Claeys, I., Simonet, G., Poels, J., Van Loy, T., Vercammen, L., De Loof, A., et al. (2002) Insulin-related peptides and their conserved signal transduction pathway. Peptides 23, 807-816.
    • (2002) Peptides , vol.23 , pp. 807-816
    • Claeys, I.1    Simonet, G.2    Poels, J.3    Van Loy, T.4    Vercammen, L.5    De Loof, A.6
  • 32
    • 84862870192 scopus 로고    scopus 로고
    • The fate of follicles after a blood meal is dependent on previtellogenic nutrition and juvenile hormone in Aedes aegypti
    • Clifton, M. E., and Noriega, F. G. (2012) The fate of follicles after a blood meal is dependent on previtellogenic nutrition and juvenile hormone in Aedes aegypti. J. Insect Physiol. 58, 1007-1019.
    • (2012) J. Insect Physiol , vol.58 , pp. 1007-1019
    • Clifton, M.E.1    Noriega, F.G.2
  • 33
    • 84860491077 scopus 로고    scopus 로고
    • Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing
    • Colombani, J., Andersen, D. S., and Leopold, P. (2012) Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing. Science 336, 582-585.
    • (2012) Science , vol.336 , pp. 582-585
    • Colombani, J.1    Andersen, D.S.2    Leopold, P.3
  • 36
  • 37
    • 77649170707 scopus 로고    scopus 로고
    • Identification of a neural circuit that underlies the effects of octopamine on sleep:wake behavior
    • Crocker, A., Shahidullah, M., Levitan, I. B., and Sehgal, A. (2010) Identification of a neural circuit that underlies the effects of octopamine on sleep:wake behavior. Neuron 65, 670-681.
    • (2010) Neuron , vol.65 , pp. 670-681
    • Crocker, A.1    Shahidullah, M.2    Levitan, I.B.3    Sehgal, A.4
  • 38
    • 38449106570 scopus 로고    scopus 로고
    • FOXO transcription factors in the regulatory networks of longevity
    • Daitoku, H., and Fukamizu, A. (2007) FOXO transcription factors in the regulatory networks of longevity. J. Biochem. 141, 769-774.
    • (2007) J. Biochem , vol.141 , pp. 769-774
    • Daitoku, H.1    Fukamizu, A.2
  • 40
    • 0000656633 scopus 로고
    • Hormonal control of vitellogenin uptake in Rhodnius prolixus Stål
    • Davey, K. G. (1981) Hormonal control of vitellogenin uptake in Rhodnius prolixus Stål. Am. Zool. 21, 701-705.
    • (1981) Am. Zool. , vol.21 , pp. 701-705
    • Davey, K.G.1
  • 41
    • 44749084339 scopus 로고    scopus 로고
    • The insulin signaling pathway in honey bee (Apis mellifera) caste development - differential expression of insulin-like peptides and insulin receptors in queen and worker larvae
    • de Azevedo, S. V., and Hartfelder, K. (2008) The insulin signaling pathway in honey bee (Apis mellifera) caste development - differential expression of insulin-like peptides and insulin receptors in queen and worker larvae. J. Insect Physiol. 54, 1064-1071.
    • (2008) J. Insect Physiol. , vol.54 , pp. 1064-1071
    • De Azevedo, S.V.1    Hartfelder, K.2
  • 42
    • 84950657389 scopus 로고
    • Alternative sites for ecdysteroid production in insects
    • Delbecque, J. P., Weidner, K., and Hoffmann, K. H. (1990) Alternative sites for ecdysteroid production in insects. Invert. Reprod. Dev. 18, 29-42.
    • (1990) Invert. Reprod. Dev. , vol.18 , pp. 29-42
    • Delbecque, J.P.1    Weidner, K.2    Hoffmann, K.H.3
  • 43
    • 0031913980 scopus 로고    scopus 로고
    • New insecticides with ecdysteroidal and juvenile hormone activity
    • Dhadialla, T. S., Carlson, G. R., and Le, D. P. (1998) New insecticides with ecdysteroidal and juvenile hormone activity. Annu. Rev. Entomol. 43, 545-569.
    • (1998) Annu. Rev. Entomol. , vol.43 , pp. 545-569
    • Dhadialla, T.S.1    Carlson, G.R.2    Le, D.P.3
  • 44
    • 0035281979 scopus 로고    scopus 로고
    • Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis
    • Drummond-Barbosa, D., and Spradling, A. C. (2001) Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. Dev. Biol. 231, 265-278.
    • (2001) Dev. Biol , vol.231 , pp. 265-278
    • Drummond-Barbosa, D.1    Spradling, A.C.2
  • 45
    • 0030732376 scopus 로고    scopus 로고
    • Alternative reproductive tactics and male-dimorphism in the horned beetle Onthophagus acuminatus (Coleoptera:Scarabaeidae) Behav
    • Emlen, D. J. (1997) Alternative reproductive tactics and male-dimorphism in the horned beetle Onthophagus acuminatus (Coleoptera:Scarabaeidae) Behav. Ecol. Sociobiol. 41, 335-341.
    • (1997) Ecol. Sociobiol , vol.41 , pp. 335-341
    • Emlen, D.J.1
  • 46
    • 84865085712 scopus 로고    scopus 로고
    • A mechanism of extreme growth and reliable signaling in sexually selected ornaments and weapons
    • Emlen, D. J., Warren, I. A., Johns, A., Dworkin, I., and Lavine, L. C. (2012) A mechanism of extreme growth and reliable signaling in sexually selected ornaments and weapons. Science 337, 860-864.
    • (2012) Science , vol.337 , pp. 860-864
    • Emlen, D.J.1    Warren, I.A.2    Johns, A.3    Dworkin, I.4    Lavine, L.C.5
  • 47
    • 78651233673 scopus 로고    scopus 로고
    • Insulin signaling, lifespan and stress resistance are modulated by metabotropic GABA receptors on insulin producing cells in the brain of Drosophila
    • Enell, L. E., Kapan, N., Söderberg, J. A., Kahsai, L., and Nässel, D. R. (2010) Insulin signaling, lifespan and stress resistance are modulated by metabotropic GABA receptors on insulin producing cells in the brain of Drosophila. PLoS ONE 5:e15780.
    • (2010) PLoS ONE , vol.5
    • Enell, L.E.1    Kapan, N.2    Söderberg, J.A.3    Kahsai, L.4    Nässel, D.R.5
  • 48
    • 84866556851 scopus 로고    scopus 로고
    • Interaction between sleep and metabolism in Drosophila with altered octopamine signaling
    • Erion, R., DiAngelo, J. R., Crocker, A., and Sehgal, A. (2012) Interaction between sleep and metabolism in Drosophila with altered octopamine signaling. J. Biol. Chem. 287, 32406-32414.
    • (2012) J. Biol. Chem , vol.287 , pp. 32406-32414
    • Erion, R.1    DiAngelo, J.R.2    Crocker, A.3    Sehgal, A.4
  • 49
    • 18844377815 scopus 로고    scopus 로고
    • Starvation affects vitellogenin production but not vitellogenin mRNA levels in the lubber grasshopper, Romalea microptera
    • Fei, H., Martin, T. R., Jaskowiak, K. M., Hatle, J. D., Whitman, D. W., and Borst, D. W. (2005) Starvation affects vitellogenin production but not vitellogenin mRNA levels in the lubber grasshopper, Romalea microptera. J. Insect Physiol. 51, 435-443.
    • (2005) J. Insect Physiol , vol.51 , pp. 435-443
    • Fei, H.1    Martin, T.R.2    Jaskowiak, K.M.3    Hatle, J.D.4    Whitman, D.W.5    Borst, D.W.6
  • 50
    • 0029070611 scopus 로고
    • The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential
    • Fernandez, R., Tabarini, D., Azpiazu, N., Frasch, M., and Schlessinger, J. (1995) The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. EMBO J. 14, 3373-3384.
    • (1995) EMBO J. , vol.14 , pp. 3373-3384
    • Fernandez, R.1    Tabarini, D.2    Azpiazu, N.3    Frasch, M.4    Schlessinger, J.5
  • 51
    • 35549006674 scopus 로고    scopus 로고
    • The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
    • Ferrandon, D., Imler, J. L., Hetru, C., and Hoffmann, J. A. (2007) The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections. Nat. Rev. Immunol. 7, 862-874.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 862-874
    • Ferrandon, D.1    Imler, J.L.2    Hetru, C.3    Hoffmann, J.A.4
  • 52
    • 27744521533 scopus 로고    scopus 로고
    • Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history
    • Flatt, T., Tu, M. P., and Tatar, M. (2005) Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history. Bioessays 27, 999-1010.
    • (2005) Bioessays , vol.27 , pp. 999-1010
    • Flatt, T.1    Tu, M.P.2    Tatar, M.3
  • 53
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span - from yeast to humans
    • Fontana, L., Partridge, L., and Longo, V. D. (2010) Extending healthy life span - from yeast to humans. Science 328, 321-326.
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 54
    • 78049317163 scopus 로고    scopus 로고
    • dDOR is an EcR coactivator that forms a feed-forward loop connecting insulin and ecdysone signaling
    • Francis, V. A., Zorzano, A., and Teleman, A. A. (2010) dDOR is an EcR coactivator that forms a feed-forward loop connecting insulin and ecdysone signaling. Curr. Biol. 20, 1799-1808.
    • (2010) Curr. Biol , vol.20 , pp. 1799-1808
    • Francis, V.A.1    Zorzano, A.2    Teleman, A.A.3
  • 55
    • 77953642134 scopus 로고    scopus 로고
    • Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan
    • Fridell, Y. W., Hoh, M., Kreneisz, O., Hosier, S., Chang, C., Scantling, D., et al. (2009) Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan. Aging 1, 699-713.
    • (2009) Aging , vol.1 , pp. 699-713
    • Fridell, Y.W.1    Hoh, M.2    Kreneisz, O.3    Hosier, S.4    Chang, C.5    Scantling, D.6
  • 56
    • 0035169995 scopus 로고    scopus 로고
    • Involvement of insulin receptor substrates in epidermal growth factor induced activation of phosphatidylinositol 3-kinase in rat hepatocyte primary culture
    • Fujioka, T., and Ui, M. (2001) Involvement of insulin receptor substrates in epidermal growth factor induced activation of phosphatidylinositol 3-kinase in rat hepatocyte primary culture. Eur. J. Biochem. 268, 25-34.
    • (2001) Eur. J. Biochem , vol.268 , pp. 25-34
    • Fujioka, T.1    Ui, M.2
  • 57
    • 0034826541 scopus 로고    scopus 로고
    • Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase
    • Fujioka, T., Kim, J. H., Adachi, H., Saito, K., Tsujimoto, M., Yokoyama, S., et al. (2001) Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase. Eur. J. Biochem. 268, 4158-4168.
    • (2001) Eur. J. Biochem , vol.268 , pp. 4158-4168
    • Fujioka, T.1    Kim, J.H.2    Adachi, H.3    Saito, K.4    Tsujimoto, M.5    Yokoyama, S.6
  • 58
    • 84864472835 scopus 로고    scopus 로고
    • Peptide signaling in Hydra
    • Fujisawa, T., and Hayakawa, E. (2012) Peptide signaling in Hydra. Int. J. Dev. Biol. 56, 543-550.
    • (2012) Int. J. Dev. Biol , vol.56 , pp. 543-550
    • Fujisawa, T.1    Hayakawa, E.2
  • 59
    • 84964892932 scopus 로고    scopus 로고
    • C. elegans AMPKs promote survival and arrest germline development during nutrient stress
    • Fukuyama, M., Sakuma, K., Park, R., Kasuga, H., Nagaya, R., Atsumi, Y., et al. (2012) C. elegans AMPKs promote survival and arrest germline development during nutrient stress. Biol. Open. 1, 929-936.
    • (2012) Biol. Open , vol.1 , pp. 929-936
    • Fukuyama, M.1    Sakuma, K.2    Park, R.3    Kasuga, H.4    Nagaya, R.5    Atsumi, Y.6
  • 60
    • 82455205805 scopus 로고    scopus 로고
    • Coordinated regulation of niche and stem cell precursors by hormonal signaling
    • Gancz, D., Lengil, T., and Gilboa, L. (2011) Coordinated regulation of niche and stem cell precursors by hormonal signaling. PLoS Biol. 9:e1001202.
    • (2011) PLoS Biol , vol.9
    • Gancz, D.1    Lengil, T.2    Gilboa, L.3
  • 61
    • 84860487216 scopus 로고    scopus 로고
    • Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation
    • Garelli, A., Gontijo, A. M., Miguela, V., Caparros, E., and Dominguez, M. (2012) Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Science 336, 579-582.
    • (2012) Science , vol.336 , pp. 579-582
    • Garelli, A.1    Gontijo, A.M.2    Miguela, V.3    Caparros, E.4    Dominguez, M.5
  • 62
    • 69149110896 scopus 로고    scopus 로고
    • Remote control of insulin secretion by fat cells in Drosophila
    • Geminard, C., Rulifson, E. J., and Leopold, P. (2009) Remote control of insulin secretion by fat cells in Drosophila. Cell Metab. 10, 199-207.
    • (2009) Cell Metab , vol.10 , pp. 199-207
    • Geminard, C.1    Rulifson, E.J.2    Leopold, P.3
  • 63
    • 0029141022 scopus 로고
    • In vitro synthesis of ecdysteroid by the male accessory reproductive glands, testis and abdominal integument of the adult migratory grasshopper, Melanoplus sanguinipes
    • Gillot, C., and Ismail, P. M. (1995) In vitro synthesis of ecdysteroid by the male accessory reproductive glands, testis and abdominal integument of the adult migratory grasshopper, Melanoplus sanguinipes. Invert. Reprod. Dev. 27, 65-71.
    • (1995) Invert. Reprod. Dev. , vol.27 , pp. 65-71
    • Gillot, C.1    Ismail, P.M.2
  • 64
    • 38249037351 scopus 로고
    • Anti-juvenile effect of neuroparsin-A, a neuroprotein isolated from locust corpora cardiaca
    • Girardie, J., Boureme, D., Couillaud, F., Tamarelle, M., and Girardie, A. (1987) Anti-juvenile effect of neuroparsin-A, a neuroprotein isolated from locust corpora cardiaca. Insect Biochem. Mol. Biol. 17, 977-983.
    • (1987) Insect Biochem. Mol. Biol , vol.17 , pp. 977-983
    • Girardie, J.1    Boureme, D.2    Couillaud, F.3    Tamarelle, M.4    Girardie, A.5
  • 65
    • 85069928600 scopus 로고    scopus 로고
    • "The juvenile hormones," in Comprehensive Molecular Insect Science, eds L. I. Gilbert and K. Iatrou (Oxford: Elsevier)
    • Goodman, W. G., and Granger, N. A. (2005) "The juvenile hormones," in Comprehensive Molecular Insect Science, eds L. I. Gilbert and K. Iatrou (Oxford: Elsevier), 319-408.
    • (2005) , pp. 319-408
    • Goodman, W.G.1    Granger, N.A.2
  • 66
    • 0031149816 scopus 로고    scopus 로고
    • Insulin-mediated secretion of ecdysteroids from mosquito ovaries and molecular cloning of the insulin receptor homologue from ovaries of bloodfed Aedes aegypti
    • Graf, R., Neuenschwander, S., Brown, M. R., and Ackermann, U. (1997) Insulin-mediated secretion of ecdysteroids from mosquito ovaries and molecular cloning of the insulin receptor homologue from ovaries of bloodfed Aedes aegypti. Insect Mol. Biol. 6, 151-163.
    • (1997) Insect Mol. Biol , vol.6 , pp. 151-163
    • Graf, R.1    Neuenschwander, S.2    Brown, M.R.3    Ackermann, U.4
  • 67
    • 79957603530 scopus 로고    scopus 로고
    • Insulin-like peptides and the target of rapamycin pathway coordinately regulate blood digestion and egg maturation in the mosquito Aedes aegypti
    • Gulia-Nuss, M., Robertson, A. E., Brown, M. R., and Strand, M. R. (2011) Insulin-like peptides and the target of rapamycin pathway coordinately regulate blood digestion and egg maturation in the mosquito Aedes aegypti. PLoS ONE 6:e20401.
    • (2011) PLoS ONE , vol.6
    • Gulia-Nuss, M.1    Robertson, A.E.2    Brown, M.R.3    Strand, M.R.4
  • 69
    • 3242684032 scopus 로고    scopus 로고
    • Target of rapamycin-mediated amino acid signaling in mosquito anautogeny
    • U.S.A.
    • Hansen, I. A., Attardo, G. M., Park, J. H., Peng, Q., and Raikhel, A. S. (2004) Target of rapamycin-mediated amino acid signaling in mosquito anautogeny. Proc. Natl. Acad. Sci. U.S.A. 101, 10626-10631.
    • (2004) Proc. Natl. Acad. Sci , vol.101 , pp. 10626-10631
    • Hansen, I.A.1    Attardo, G.M.2    Park, J.H.3    Peng, Q.4    Raikhel, A.S.5
  • 70
    • 20144366618 scopus 로고    scopus 로고
    • Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito
    • Hansen, I. A., Attardo, G. M., Roy, S. G., and Raikhel, A. S. (2005) Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito. J. Biol. Chem. 280, 20565-20572.
    • (2005) J. Biol. Chem , vol.280 , pp. 20565-20572
    • Hansen, I.A.1    Attardo, G.M.2    Roy, S.G.3    Raikhel, A.S.4
  • 71
    • 0034132093 scopus 로고    scopus 로고
    • Insect juvenile hormone: from "status quo" to high society
    • Hartfelder, K. (2000) Insect juvenile hormone: from "status quo" to high society. Braz. J. Med. Biol. Res. 33, 157-177.
    • (2000) Braz. J. Med. Biol. Res , vol.33 , pp. 157-177
    • Hartfelder, K.1
  • 72
    • 0030240428 scopus 로고    scopus 로고
    • Insect storage proteins: gene families and receptors
    • Haunerland, N. H. (1996) Insect storage proteins: gene families and receptors. Insect Biochem. Mol. Biol. 26, 755-765.
    • (1996) Insect Biochem. Mol. Biol , vol.26 , pp. 755-765
    • Haunerland, N.H.1
  • 73
    • 70349469577 scopus 로고    scopus 로고
    • The cunning little vixen: Foxo and the cycle of life and death
    • Hedrick, S. M. (2009) The cunning little vixen: Foxo and the cycle of life and death. Nat. Immunol. 10, 1057-1063.
    • (2009) Nat. Immunol , vol.10 , pp. 1057-1063
    • Hedrick, S.M.1
  • 74
    • 0031727582 scopus 로고    scopus 로고
    • Localization of the mosquito insulin receptor homolog (MIR) in reproducing yellow fever mosquitoes (Aedes aegypti) J
    • Helbling, P., and Graf, R. (1998) Localization of the mosquito insulin receptor homolog (MIR) in reproducing yellow fever mosquitoes (Aedes aegypti) J. Insect Physiol. 44, 1127-1135.
    • (1998) Insect Physiol. , vol.44 , pp. 1127-1135
    • Helbling, P.1    Graf, R.2
  • 75
    • 33847410620 scopus 로고    scopus 로고
    • Role of juvenile hormone and allatotropin on nutrient allocation, ovarian development and survivorship in mosquitoes
    • Hernandez-Martinez, S., Mayoral, J. G., Li, Y., and Noriega, F. G. (2007) Role of juvenile hormone and allatotropin on nutrient allocation, ovarian development and survivorship in mosquitoes. J. Insect Physiol. 53, 230-234.
    • (2007) J. Insect Physiol. , vol.53 , pp. 230-234
    • Hernandez-Martinez, S.1    Mayoral, J.G.2    Li, Y.3    Noriega, F.G.4
  • 76
    • 0026048601 scopus 로고
    • Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta Migratoria
    • Hetru, C., Li, K. W., Bulet, P., Lagueux, M., and Hoffmann, J. A. (1991) Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta Migratoria. Eur. J. Biochem. 201, 495-499.
    • (1991) Eur. J. Biochem , vol.201 , pp. 495-499
    • Hetru, C.1    Li, K.W.2    Bulet, P.3    Lagueux, M.4    Hoffmann, J.A.5
  • 77
    • 73349138892 scopus 로고    scopus 로고
    • Regulation of tissue growth through nutrient sensing
    • Hietakangas, V., and Cohen, S. M. (2009) Regulation of tissue growth through nutrient sensing. Annu. Rev. Genet. 43, 389-410.
    • (2009) Annu. Rev. Genet , vol.43 , pp. 389-410
    • Hietakangas, V.1    Cohen, S.M.2
  • 78
    • 42249108516 scopus 로고    scopus 로고
    • Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance
    • Honegger, B., Galic, M., Kohler, K., Wittwer, F., Brogiolo, W., Hafen, E., et al. (2008) Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. J. Biol. 7, 10.
    • (2008) J. Biol. , vol.7 , pp. 10
    • Honegger, B.1    Galic, M.2    Kohler, K.3    Wittwer, F.4    Brogiolo, W.5    Hafen, E.6
  • 79
    • 84866522044 scopus 로고    scopus 로고
    • Small GTPase Rab4b participates in the gene transcription of 20-hydroxyecdysone and insulin pathways to regulate glycogen level and metamorphosis
    • Hou, L., Cai, M. J., Liu, W., Song, Q., and Zhao, X. F. (2012) Small GTPase Rab4b participates in the gene transcription of 20-hydroxyecdysone and insulin pathways to regulate glycogen level and metamorphosis. Dev. Biol. 371, 13-22.
    • (2012) Dev. Biol , vol.371 , pp. 13-22
    • Hou, L.1    Cai, M.J.2    Liu, W.3    Song, Q.4    Zhao, X.F.5
  • 80
    • 37849019064 scopus 로고    scopus 로고
    • Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila
    • Hsu, H. J., LaFever, L., and Drummond-Barbosa, D. (2008) Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila. Dev. Biol. 313, 700-712.
    • (2008) Dev. Biol , vol.313 , pp. 700-712
    • Hsu, H.J.1    LaFever, L.2    Drummond-Barbosa, D.3
  • 81
    • 59749091850 scopus 로고    scopus 로고
    • A complex interplay between Akt, TSC2 and the two mTOR complexes
    • Huang, J., and Manning, B. D. (2009) A complex interplay between Akt, TSC2 and the two mTOR complexes. Biochem. Soc. Trans. 37, 217-222.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 217-222
    • Huang, J.1    Manning, B.D.2
  • 82
    • 0000914902 scopus 로고
    • Induction of vitellogenin synthesis in male Sarcophaga bullata by ecdysterone
    • Huybrechts, R., and De Loof, A. (1977) Induction of vitellogenin synthesis in male Sarcophaga bullata by ecdysterone. J. Insect Physiol. 23, 1359-1362.
    • (1977) J. Insect Physiol , vol.23 , pp. 1359-1362
    • Huybrechts, R.1    De Loof, A.2
  • 83
    • 0037031147 scopus 로고    scopus 로고
    • Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila
    • Ikeya, T., Galic, M., Belawat, P., Nairz, K., and Hafen, E. (2002) Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Curr. Biol. 12, 1293-1300.
    • (2002) Curr. Biol , vol.12 , pp. 1293-1300
    • Ikeya, T.1    Galic, M.2    Belawat, P.3    Nairz, K.4    Hafen, E.5
  • 84
    • 38249041304 scopus 로고
    • Metabolic shift from lipogenesis to glycogenesis in the last instar larval fat body of the silkworm, Bombyx mori
    • Inagaki, S., and Yamashita, O. (1986) Metabolic shift from lipogenesis to glycogenesis in the last instar larval fat body of the silkworm, Bombyx mori. Insect Biochem. 16, 327-331.
    • (1986) Insect Biochem , vol.16 , pp. 327-331
    • Inagaki, S.1    Yamashita, O.2
  • 85
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki, K., Zhu, T., and Guan, K. L. (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115, 577-590.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 86
    • 0034310261 scopus 로고    scopus 로고
    • Bombyxin: an insect brain peptide that belongs to the insulin family
    • Iwami, M. (2000) Bombyxin: an insect brain peptide that belongs to the insulin family. Zool. Sci. 17, 1035-1044.
    • (2000) Zool. Sci , vol.17 , pp. 1035-1044
    • Iwami, M.1
  • 87
    • 0029817054 scopus 로고    scopus 로고
    • Bombyxin gene expression in tissues other than brain detected by reverse transcription polymerase chain reaction (RT-PCR) and in situ hybridization
    • Iwami, M., Tanaka, A., Hano, N., and Sakurai, S. (1996) Bombyxin gene expression in tissues other than brain detected by reverse transcription polymerase chain reaction (RT-PCR) and in situ hybridization. Experientia 52, 882-887.
    • (1996) Experientia , vol.52 , pp. 882-887
    • Iwami, M.1    Tanaka, A.2    Hano, N.3    Sakurai, S.4
  • 88
    • 84863685771 scopus 로고    scopus 로고
    • Conserved microRNA miR-8 controls body size in response to steroid signaling in Drosophila
    • Jin, H., Kim, V. N., and Hyun, S. (2012) Conserved microRNA miR-8 controls body size in response to steroid signaling in Drosophila. Genes Dev. 26, 1427-1432.
    • (2012) Genes Dev , vol.26 , pp. 1427-1432
    • Jin, H.1    Kim, V.N.2    Hyun, S.3
  • 89
    • 79957613433 scopus 로고    scopus 로고
    • Royalactin induces queen differentiation in honeybees
    • Kamakura, M. (2011) Royalactin induces queen differentiation in honeybees. Nature 473, 478-483.
    • (2011) Nature , vol.473 , pp. 478-483
    • Kamakura, M.1
  • 91
    • 76849084865 scopus 로고    scopus 로고
    • Neuropeptides, hormone peptides, and their receptors in Ciona intestinalis: an update
    • Kawada, T., Sekiguchi, T., Sakai, T., Aoyama, M., and Satake, H. (2010) Neuropeptides, hormone peptides, and their receptors in Ciona intestinalis: an update. Zoolog. Sci. 27, 134-153.
    • (2010) Zoolog. Sci , vol.27 , pp. 134-153
    • Kawada, T.1    Sekiguchi, T.2    Sakai, T.3    Aoyama, M.4    Satake, H.5
  • 92
    • 79955015948 scopus 로고    scopus 로고
    • Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation
    • Konig, A., Yatsenko, A. S., Weiss, M., and Shcherbata, H. R. (2011) Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation. EMBO J. 30, 1549-1562.
    • (2011) EMBO J , vol.30 , pp. 1549-1562
    • Konig, A.1    Yatsenko, A.S.2    Weiss, M.3    Shcherbata, H.R.4
  • 94
    • 70749146766 scopus 로고    scopus 로고
    • Structure determination of a new juvenile hormone from a heteropteran insect
    • Kotaki, T., Shinada, T., Kaihara, K., Ohfune, Y., and Numata, H. (2009) Structure determination of a new juvenile hormone from a heteropteran insect. Org. Lett. 11, 5234-5237.
    • (2009) Org. Lett. , vol.11 , pp. 5234-5237
    • Kotaki, T.1    Shinada, T.2    Kaihara, K.3    Ohfune, Y.4    Numata, H.5
  • 96
    • 49249121567 scopus 로고    scopus 로고
    • Foxo is required for resistance to amino acid starvation in Drosophila
    • Kramer, J. M., Slade, J. D., and Staveley, B. E. (2008) Foxo is required for resistance to amino acid starvation in Drosophila. Genome 51, 668-672.
    • (2008) Genome , vol.51 , pp. 668-672
    • Kramer, J.M.1    Slade, J.D.2    Staveley, B.E.3
  • 97
    • 78349310619 scopus 로고    scopus 로고
    • Glucose increases activity and Ca2+ in insulin-producing cells of adult Drosophila
    • Kreneisz, O., Chen, X., Fridell, Y. W., and Mulkey, D. K. (2010) Glucose increases activity and Ca2+ in insulin-producing cells of adult Drosophila. Neuroreport 21, 1116-1120.
    • (2010) Neuroreport , vol.21 , pp. 1116-1120
    • Kreneisz, O.1    Chen, X.2    Fridell, Y.W.3    Mulkey, D.K.4
  • 99
    • 23644444460 scopus 로고    scopus 로고
    • Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila
    • LaFever, L., and Drummond-Barbosa, D. (2005) Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila. Science 309, 1071-1073.
    • (2005) Science , vol.309 , pp. 1071-1073
    • LaFever, L.1    Drummond-Barbosa, D.2
  • 102
    • 84871715850 scopus 로고    scopus 로고
    • Cloning and characterization of an mRNA encoding an insulin receptor from the horned scarab beetle Onthophagus nigriventris (Coleoptera: Scarabaeidae) Arch
    • Lavine, L. C., Hahn, L. L., Warren, I. A., Garczynski, S. F., Dworkin, I., and Emlen, D. J. (2013) Cloning and characterization of an mRNA encoding an insulin receptor from the horned scarab beetle Onthophagus nigriventris (Coleoptera: Scarabaeidae) Arch. Insect Biochem. Physiol 82, 43-57.
    • (2013) Insect Biochem. Physiol , vol.82 , pp. 43-57
    • Lavine, L.C.1    Hahn, L.L.2    Warren, I.A.3    Garczynski, S.F.4    Dworkin, I.5    Emlen, D.J.6
  • 103
    • 84884552053 scopus 로고
    • "Neuropeptides of mosquitoes," in Molecular Insect Science, eds H.H. Hagedorn, J. G. Hildebrand, M. G. Kidwell. J. H. Law (New York, NY: Plenum Press)
    • Lea, A. O., and Brown, M. R. (1990) "Neuropeptides of mosquitoes," in Molecular Insect Science, eds H. H. Hagedorn, J. G. Hildebrand, M. G. Kidwell, and J. H. Law (New York, NY: Plenum Press)
    • (1990)
    • Lea, A.O.1    Brown, M.R.2
  • 104
    • 67849119263 scopus 로고    scopus 로고
    • Processed short neuropeptide F peptides regulate growth through the ERK-insulin pathway in Drosophila melanogaster
    • Lee, K. S., Hong, S. H., Kim, A. K., Ju, S. K., Kwon, O. Y., and Yu, K. (2009) Processed short neuropeptide F peptides regulate growth through the ERK-insulin pathway in Drosophila melanogaster. FEBS Lett. 583, 2573-2577.
    • (2009) FEBS Lett , vol.583 , pp. 2573-2577
    • Lee, K.S.1    Hong, S.H.2    Kim, A.K.3    Ju, S.K.4    Kwon, O.Y.5    Yu, K.6
  • 105
    • 43149111605 scopus 로고    scopus 로고
    • Drosophila short neuropeptide F signalling regulates growth by ERK-mediated insulin signalling
    • Lee, K. S., Kwon, O. Y., Lee, J. H., Kwon, K., Min, K. J., Jung, S. A., et al. (2008) Drosophila short neuropeptide F signalling regulates growth by ERK-mediated insulin signalling. Nat. Cell Biol. 10, 468-475.
    • (2008) Nat. Cell Biol , vol.10 , pp. 468-475
    • Lee, K.S.1    Kwon, O.Y.2    Lee, J.H.3    Kwon, K.4    Min, K.J.5    Jung, S.A.6
  • 106
    • 0030657540 scopus 로고    scopus 로고
    • daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin, K., Dorman, J. B., Rodan, A., and Kenyon, C. (1997) daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322.
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 107
    • 34548445981 scopus 로고    scopus 로고
    • Co-regulation of cold-resistant food acquisition by insulin- and neuropeptide Y-like systems in Drosophila melanogaster
    • Lingo, P. R., Zhao, Z., and Shen, P. (2007) Co-regulation of cold-resistant food acquisition by insulin- and neuropeptide Y-like systems in Drosophila melanogaster. Neuroscience 148, 371-374.
    • (2007) Neuroscience , vol.148 , pp. 371-374
    • Lingo, P.R.1    Zhao, Z.2    Shen, P.3
  • 108
    • 77955431617 scopus 로고    scopus 로고
    • Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body
    • Liu, Y., Zhou, S., Ma, L., Tian, L., Wang, S., Sheng, Z., et al. (2010) Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body. J. Insect Physiol 56, 1436-1444.
    • (2010) J. Insect Physiol , vol.56 , pp. 1436-1444
    • Liu, Y.1    Zhou, S.2    Ma, L.3    Tian, L.4    Wang, S.5    Sheng, Z.6
  • 109
    • 80052961876 scopus 로고    scopus 로고
    • Insect insulin receptors: insights from sequence and caste expression analyses of two cloned hymenopteran insulin receptor cDNAs from the fire ant
    • Lu, H. L., and Pietrantonio, P. V. (2011) Insect insulin receptors: insights from sequence and caste expression analyses of two cloned hymenopteran insulin receptor cDNAs from the fire ant. Insect Mol. Biol. 20, 637-649.
    • (2011) Insect Mol. Biol , vol.20 , pp. 637-649
    • Lu, H.L.1    Pietrantonio, P.V.2
  • 110
    • 78651101672 scopus 로고    scopus 로고
    • The regulation of feeding and metabolism in response to food deprivation in Caenorhabditis elegans
    • Luedtke, S., O'Connor, V., Holden-Dye, L., and Walker, R. J. (2010) The regulation of feeding and metabolism in response to food deprivation in Caenorhabditis elegans. Invert. Neurosci. 10, 63-76.
    • (2010) Invert. Neurosci , vol.10 , pp. 63-76
    • Luedtke, S.1    O'Connor, V.2    Holden-Dye, L.3    Walker, R.J.4
  • 111
    • 84856211184 scopus 로고    scopus 로고
    • Insulin-producing cells in the brain of adult Drosophila are regulated by the serotonin 5-HT1A receptor
    • Luo, J., Becnel, J., Nichols, C. D., and Nassel, D. R. (2012) Insulin-producing cells in the brain of adult Drosophila are regulated by the serotonin 5-HT1A receptor. Cell Mol. Life Sci. 69, 471-484.
    • (2012) Cell Mol. Life Sci , vol.69 , pp. 471-484
    • Luo, J.1    Becnel, J.2    Nichols, C.D.3    Nassel, D.R.4
  • 112
    • 67649413033 scopus 로고    scopus 로고
    • Control of ovarian steroidogenesis in insects: a locust neurohormone is active in vitro on blowfly ovaries
    • Maniere, G., Vanhems, E., Rondot, I., and Delbecque, J. P. (2009) Control of ovarian steroidogenesis in insects: a locust neurohormone is active in vitro on blowfly ovaries. Gen. Comp. Endocrinol. 163, 292-297.
    • (2009) Gen. Comp. Endocrinol , vol.163 , pp. 292-297
    • Maniere, G.1    Vanhems, E.2    Rondot, I.3    Delbecque, J.P.4
  • 113
    • 80052666671 scopus 로고    scopus 로고
    • The genetic basis of rapidly evolving male genital morphology in Drosophila
    • Masly, J. P., Dalton, J. E., Srivastava, S., Chen, L., and Arbeitman, M. N. (2011) The genetic basis of rapidly evolving male genital morphology in Drosophila. Genetics 189, 357-374.
    • (2011) Genetics , vol.189 , pp. 357-374
    • Masly, J.P.1    Dalton, J.E.2    Srivastava, S.3    Chen, L.4    Arbeitman, M.N.5
  • 114
    • 0034122589 scopus 로고    scopus 로고
    • Glucose stimulates the release of bombyxin, an insulin-related peptide of the silkworm Bombyx mori
    • Masumura, M., Satake, S. I., Saegusa, H., and Mizoguchi, A. (2000) Glucose stimulates the release of bombyxin, an insulin-related peptide of the silkworm Bombyx mori. Gen. Comp. Endocrinol. 118, 393-399.
    • (2000) Gen. Comp. Endocrinol , vol.118 , pp. 393-399
    • Masumura, M.1    Satake, S.I.2    Saegusa, H.3    Mizoguchi, A.4
  • 115
    • 78650175195 scopus 로고    scopus 로고
    • Stem cell dynamics in response to nutrient availability
    • McLeod, C. J., Wang, L., Wong, C., and Jones, D. L. (2010) Stem cell dynamics in response to nutrient availability. Curr. Biol. 20, 2100-2105.
    • (2010) Curr. Biol , vol.20 , pp. 2100-2105
    • McLeod, C.J.1    Wang, L.2    Wong, C.3    Jones, D.L.4
  • 116
    • 34247107090 scopus 로고    scopus 로고
    • Size assessment and growth control: how adult size is determined in insects
    • Mirth, C. K., and Riddiford, L. M. (2007) Size assessment and growth control: how adult size is determined in insects. Bioessays 29, 344-355.
    • (2007) Bioessays , vol.29 , pp. 344-355
    • Mirth, C.K.1    Riddiford, L.M.2
  • 117
    • 0027762356 scopus 로고
    • Effects of intestinal insulin-like peptide on glucose catabolism in mealworm larval fat body in vitro: dependence on extracellular Ca2+ for its stimulatory action
    • Mtioui, A., Gourdoux, L., Fournier, B., and Moreau, R. (1993) Effects of intestinal insulin-like peptide on glucose catabolism in mealworm larval fat body in vitro: dependence on extracellular Ca2+ for its stimulatory action. Arch. Insect Biochem. Physiol 24, 113-128.
    • (1993) Arch. Insect Biochem. Physiol , vol.24 , pp. 113-128
    • Mtioui, A.1    Gourdoux, L.2    Fournier, B.3    Moreau, R.4
  • 119
    • 82055198025 scopus 로고    scopus 로고
    • IRS and TOR nutrient-signaling pathways act via juvenile hormone to influence honey bee caste fate
    • Mutti, N. S., Dolezal, A. G., Wolschin, F., Mutti, J. S., Gill, K. S., and Amdam, G. V. (2011) IRS and TOR nutrient-signaling pathways act via juvenile hormone to influence honey bee caste fate. J. Exp. Biol. 214, 3977-3984.
    • (2011) J. Exp. Biol , vol.214 , pp. 3977-3984
    • Mutti, N.S.1    Dolezal, A.G.2    Wolschin, F.3    Mutti, J.S.4    Gill, K.S.5    Amdam, G.V.6
  • 120
    • 84859310616 scopus 로고    scopus 로고
    • Insulin-producing cells and their regulation in physiology and behavior of Drosophila
    • Nassel, D. R. (2012) Insulin-producing cells and their regulation in physiology and behavior of Drosophila. Can. J. Zool. 90, 476-488.
    • (2012) Can. J. Zool , vol.90 , pp. 476-488
    • Nassel, D.R.1
  • 121
    • 79955045942 scopus 로고    scopus 로고
    • Insulin-like peptide genes in honey bee fat body respond differently to manipulation of social behavioral physiology
    • Nilsen, K. A., Ihle, K. E., Frederick, K., Fondrk, M. K., Smedal, B., Hartfelder, K., et al. (2011) Insulin-like peptide genes in honey bee fat body respond differently to manipulation of social behavioral physiology. J. Exp. Biol. 214, 1488-1497.
    • (2011) J. Exp. Biol , vol.214 , pp. 1488-1497
    • Nilsen, K.A.1    Ihle, K.E.2    Frederick, K.3    Fondrk, M.K.4    Smedal, B.5    Hartfelder, K.6
  • 122
    • 3142575614 scopus 로고    scopus 로고
    • Nutritional regulation of JH synthesis: a mechanism to control reproductive maturation in mosquitoes?
    • Noriega, F. G. (2004) Nutritional regulation of JH synthesis: a mechanism to control reproductive maturation in mosquitoes? Insect Biochem. Mol. Biol. 34, 687-693.
    • (2004) Insect Biochem. Mol. Biol , vol.34 , pp. 687-693
    • Noriega, F.G.1
  • 123
    • 79959784972 scopus 로고    scopus 로고
    • A coordinated expression of biosynthetic enzymes controls the flux of juvenile hormone precursors in the corpora allata of mosquitoes
    • Nouzova, M., Edwards, M. J., Mayoral, J. G., and Noriega, F. G. (2011) A coordinated expression of biosynthetic enzymes controls the flux of juvenile hormone precursors in the corpora allata of mosquitoes. Insect Biochem. Mol. Biol. 41, 660-669.
    • (2011) Insect Biochem. Mol. Biol , vol.41 , pp. 660-669
    • Nouzova, M.1    Edwards, M.J.2    Mayoral, J.G.3    Noriega, F.G.4
  • 124
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg, S., Paradis, S., Gottlieb, S., Patterson, G. I., Lee, L., Tissenbaum, H. A., et al. (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389, 994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5    Tissenbaum, H.A.6
  • 125
    • 75749148305 scopus 로고    scopus 로고
    • Ovarian development and insulin-signaling pathways during reproductive differentiation in the queenless ponerine ant Diacamma sp
    • Okada, Y., Miyazaki, S., Miyakawa, H., Ishikawa, A., Tsuji, K., and Miura, T. (2010) Ovarian development and insulin-signaling pathways during reproductive differentiation in the queenless ponerine ant Diacamma sp. J. Insect Physiol 56, 288-295.
    • (2010) J. Insect Physiol , vol.56 , pp. 288-295
    • Okada, Y.1    Miyazaki, S.2    Miyakawa, H.3    Ishikawa, A.4    Tsuji, K.5    Miura, T.6
  • 126
    • 79959877416 scopus 로고    scopus 로고
    • Spatiotemporal patterns of IGF-like peptide expression in the silkmoth Bombyx mori predict its pleiotropic actions
    • Okamoto, N., Yamanaka, N., Endo, Y., Kataoka, H., and Mizoguchi, A. (2011) Spatiotemporal patterns of IGF-like peptide expression in the silkmoth Bombyx mori predict its pleiotropic actions. Gen. Comp. Endocrinol. 173, 171-182.
    • (2011) Gen. Comp. Endocrinol , vol.173 , pp. 171-182
    • Okamoto, N.1    Yamanaka, N.2    Endo, Y.3    Kataoka, H.4    Mizoguchi, A.5
  • 127
    • 60349121476 scopus 로고    scopus 로고
    • An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori
    • Okamoto, N., Yamanaka, N., Satake, H., Saegusa, H., Kataoka, H., and Mizoguchi, A. (2009) An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori. FEBS J. 276, 1221-1232.
    • (2009) FEBS J. , vol.276 , pp. 1221-1232
    • Okamoto, N.1    Yamanaka, N.2    Satake, H.3    Saegusa, H.4    Kataoka, H.5    Mizoguchi, A.6
  • 128
    • 0034312279 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
    • Oldham, S., Montagne, J., Radimerski, T., Thomas, G., and Hafen, E. (2000) Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes Dev. 14, 2689-2694.
    • (2000) Genes Dev , vol.14 , pp. 2689-2694
    • Oldham, S.1    Montagne, J.2    Radimerski, T.3    Thomas, G.4    Hafen, E.5
  • 129
    • 0027468233 scopus 로고
    • A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos
    • Olivier, J. P., Raabe, T., Henkemeyer, M., Dickson, B., Mbamalu, G., Margolis, B., et al. (1993) A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell 73, 179-191.
    • (1993) Cell , vol.73 , pp. 179-191
    • Olivier, J.P.1    Raabe, T.2    Henkemeyer, M.3    Dickson, B.4    Mbamalu, G.5    Margolis, B.6
  • 130
    • 33645055092 scopus 로고    scopus 로고
    • Flies on steroids: the interplay between ecdysone and insulin signaling
    • Orme, M. H., and Leevers, S. J. (2005) Flies on steroids: the interplay between ecdysone and insulin signaling. Cell Metab 2, 277-278.
    • (2005) Cell Metab , vol.2 , pp. 277-278
    • Orme, M.H.1    Leevers, S.J.2
  • 131
    • 0036796288 scopus 로고    scopus 로고
    • A homologue of AMP-activated protein kinase in Drosophila melanogaster is sensitive to AMP and is activated by ATP depletion
    • Pan, D. A., and Hardie, D. G. (2002) A homologue of AMP-activated protein kinase in Drosophila melanogaster is sensitive to AMP and is activated by ATP depletion. Biochem. J. 367(Pt 1), 179-186.
    • (2002) Biochem. J. , vol.367 , Issue.PART 1 , pp. 179-186
    • Pan, D.A.1    Hardie, D.G.2
  • 132
    • 79953039527 scopus 로고    scopus 로고
    • Molecular analysis of nutritional and hormonal regulation of female reproduction in the red flour beetle, Tribolium castaneum
    • Parthasarathy, R., and Palli, S. R. (2011) Molecular analysis of nutritional and hormonal regulation of female reproduction in the red flour beetle, Tribolium castaneum. Insect Biochem. Mol. Biol. 41, 294-305.
    • (2011) Insect Biochem. Mol. Biol , vol.41 , pp. 294-305
    • Parthasarathy, R.1    Palli, S.R.2
  • 133
    • 77953135520 scopus 로고    scopus 로고
    • Ecdysteroid regulation of ovarian growth and oocyte maturation in the red flour beetle, Tribolium castaneum
    • Parthasarathy, R., Sheng, Z., Sun, Z., and Palli, S. R. (2010) Ecdysteroid regulation of ovarian growth and oocyte maturation in the red flour beetle, Tribolium castaneum. Insect Biochem. Mol. Biol. 40, 429-439.
    • (2010) Insect Biochem. Mol. Biol. , vol.40 , pp. 429-439
    • Parthasarathy, R.1    Sheng, Z.2    Sun, Z.3    Palli, S.R.4
  • 134
    • 0026847450 scopus 로고
    • Environmental cues, endocrine factors, and reproductive diapause in male insects
    • Pener, M. P. (1992) Environmental cues, endocrine factors, and reproductive diapause in male insects. Chronobiol. Int. 9, 102-113.
    • (1992) Chronobiol. Int , vol.9 , pp. 102-113
    • Pener, M.P.1
  • 135
    • 84876716624 scopus 로고    scopus 로고
    • The insulin/TOR signal transduction pathway is involved in the nutritional regulation of juvenile hormone synthesis in Aedes aegypti
    • Perez-Hedo, M., Rivera-Perez, C., and Noriega, F. G. (2013) The insulin/TOR signal transduction pathway is involved in the nutritional regulation of juvenile hormone synthesis in Aedes aegypti. Insect Biochem. Mol. Biol. 43, 495-500.
    • (2013) Insect Biochem. Mol. Biol , vol.43 , pp. 495-500
    • Perez-Hedo, M.1    Rivera-Perez, C.2    Noriega, F.G.3
  • 136
    • 84860748872 scopus 로고    scopus 로고
    • Role of the insulin/Tor signaling network in starvation-induced programmed cell death in Drosophila oogenesis
    • Pritchett, T. L., and McCall, K. (2012) Role of the insulin/Tor signaling network in starvation-induced programmed cell death in Drosophila oogenesis. Cell Death Differ. 19, 1069-1079.
    • (2012) Cell Death Differ , vol.19 , pp. 1069-1079
    • Pritchett, T.L.1    McCall, K.2
  • 137
    • 33644779774 scopus 로고    scopus 로고
    • Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1
    • Puig, O., and Tjian, R. (2006) Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1. Cell Cycle 5, 503-505.
    • (2006) Cell Cycle , vol.5 , pp. 503-505
    • Puig, O.1    Tjian, R.2
  • 138
    • 0026449642 scopus 로고
    • Accumulation of yolk proteins in insect oocytes
    • Raikhel, A. S., and Dhadialla, T. S. (1992) Accumulation of yolk proteins in insect oocytes. Annu. Rev. Entomol. 37, 217-251.
    • (1992) Annu. Rev. Entomol , vol.37 , pp. 217-251
    • Raikhel, A.S.1    Dhadialla, T.S.2
  • 139
    • 84866978180 scopus 로고    scopus 로고
    • Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion
    • Rajan, A., and Perrimon, N. (2012) Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell 151, 123-137.
    • (2012) Cell , vol.151 , pp. 123-137
    • Rajan, A.1    Perrimon, N.2
  • 140
    • 13944279429 scopus 로고    scopus 로고
    • Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary
    • Richard, D. S., Rybczynski, R., Wilson, T. G., Wang, Y., Wayne, M. L., Zhou, Y., et al. (2005) Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary. J. Insect Physiol. 51, 455-464.
    • (2005) J. Insect Physiol , vol.51 , pp. 455-464
    • Richard, D.S.1    Rybczynski, R.2    Wilson, T.G.3    Wang, Y.4    Wayne, M.L.5    Zhou, Y.6
  • 141
    • 0033215285 scopus 로고    scopus 로고
    • Insulin stimulates ecdysteroid production through a conserved signaling cascade in the mosquito Aedes aegypti
    • Riehle, M. A., and Brown, M. R. (1999) Insulin stimulates ecdysteroid production through a conserved signaling cascade in the mosquito Aedes aegypti. Insect Biochem. Mol. Biol. 29, 855-860.
    • (1999) Insect Biochem. Mol. Biol , vol.29 , pp. 855-860
    • Riehle, M.A.1    Brown, M.R.2
  • 142
    • 0035989152 scopus 로고    scopus 로고
    • Insulin receptor expression during development and a reproductive cycle in the ovary of the mosquito Aedes aegypti
    • Riehle, M. A., and Brown, M. R. (2002) Insulin receptor expression during development and a reproductive cycle in the ovary of the mosquito Aedes aegypti. Cell Tissue Res. 308, 409-420.
    • (2002) Cell Tissue Res , vol.308 , pp. 409-420
    • Riehle, M.A.1    Brown, M.R.2
  • 143
    • 77954382783 scopus 로고    scopus 로고
    • Morpho-physiological analysis of the insect fat body: a review
    • Roma, G. C., Bueno, O. C., and Camargo-Mathias, M. I. (2010) Morpho-physiological analysis of the insect fat body: a review. Micron 41, 395-401.
    • (2010) Micron , vol.41 , pp. 395-401
    • Roma, G.C.1    Bueno, O.C.2    Camargo-Mathias, M.I.3
  • 144
    • 78651225262 scopus 로고    scopus 로고
    • The small GTPase Rheb is a key component linking amino acid signaling and TOR in the nutritional pathway that controls mosquito egg development
    • Roy, S. G., and Raikhel, A. S. (2011) The small GTPase Rheb is a key component linking amino acid signaling and TOR in the nutritional pathway that controls mosquito egg development. Insect Biochem. Mol. Biol. 41, 62-69.
    • (2011) Insect Biochem. Mol. Biol , vol.41 , pp. 62-69
    • Roy, S.G.1    Raikhel, A.S.2
  • 145
    • 35448941973 scopus 로고    scopus 로고
    • Effect of insulin and 20-hydroxyecdysone in the fat body of the yellow fever mosquito, Aedes aegypti
    • Roy, S. G., Hansen, I. A., and Raikhel, A. S. (2007) Effect of insulin and 20-hydroxyecdysone in the fat body of the yellow fever mosquito, Aedes aegypti. Insect Biochem. Mol. Biol. 37, 1317-1326.
    • (2007) Insect Biochem. Mol. Biol , vol.37 , pp. 1317-1326
    • Roy, S.G.1    Hansen, I.A.2    Raikhel, A.S.3
  • 146
    • 47549115043 scopus 로고    scopus 로고
    • Serotonin and insulin signaling team up to control growth in Drosophila
    • Ruaud, A. F., and Thummel, C. S. (2008) Serotonin and insulin signaling team up to control growth in Drosophila. Genes Dev. 22, 1851-1855.
    • (2008) Genes Dev , vol.22 , pp. 1851-1855
    • Ruaud, A.F.1    Thummel, C.S.2
  • 148
    • 0001238886 scopus 로고    scopus 로고
    • Reproductive biology of the German cockroach, Blattella germanica: juvenile hormone as a pleiotropic master regulator
    • Schal, C., Holbrook, G. L., Bachmann, J. A. S., and Sevala, V. L. (1997) Reproductive biology of the German cockroach, Blattella germanica: juvenile hormone as a pleiotropic master regulator. Arch. Insect Biochem. Physiol. 35, 405-426.
    • (1997) Arch. Insect Biochem. Physiol , vol.35 , pp. 405-426
    • Schal, C.1    Holbrook, G.L.2    Bachmann, J.A.S.3    Sevala, V.L.4
  • 149
    • 32244433600 scopus 로고    scopus 로고
    • Reproductive protein protects functionally sterile honey bee workers from oxidative stress
    • U.S.A.
    • Seehuus, S. C., Norberg, K., Gimsa, U., Krekling, T., and Amdam, G. V. (2006) Reproductive protein protects functionally sterile honey bee workers from oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 103, 962-967.
    • (2006) Proc. Natl. Acad. Sci , vol.103 , pp. 962-967
    • Seehuus, S.C.1    Norberg, K.2    Gimsa, U.3    Krekling, T.4    Amdam, G.V.5
  • 150
    • 34547204160 scopus 로고    scopus 로고
    • The MEK/ERK cascade: from signaling specificity to diverse functions
    • Shaul, Y. D., and Seger, R. (2007) The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim. Biophys. Acta 1773, 1213-1226.
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1213-1226
    • Shaul, Y.D.1    Seger, R.2
  • 151
    • 82755171845 scopus 로고    scopus 로고
    • Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum
    • Sheng, Z., Xu, J., Bai, H., Zhu, F., and Palli, S. R. (2011) Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum. J. Biol. Chem. 286, 41924-41936.
    • (2011) J. Biol. Chem , vol.286 , pp. 41924-41936
    • Sheng, Z.1    Xu, J.2    Bai, H.3    Zhu, F.4    Palli, S.R.5
  • 152
    • 0032143284 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: the key switch in insulin signalling
    • Shepherd, P. R., Withers, D. J., and Siddle, K. (1998) Phosphoinositide 3-kinase: the key switch in insulin signalling. Biochem. J. 333, 471-490.
    • (1998) Biochem. J. , vol.333 , pp. 471-490
    • Shepherd, P.R.1    Withers, D.J.2    Siddle, K.3
  • 154
    • 0033918523 scopus 로고    scopus 로고
    • Structural and functional characterization of insulin receptor substrate proteins and the molecular mechanisms of their interaction with insulin superfamily tyrosine kinase receptors and effector proteins
    • Shpakov, A. O., and Pertseva, M. N. (2000) Structural and functional characterization of insulin receptor substrate proteins and the molecular mechanisms of their interaction with insulin superfamily tyrosine kinase receptors and effector proteins. Membr. Cell Biol. 13, 455-484.
    • (2000) Membr. Cell Biol , vol.13 , pp. 455-484
    • Shpakov, A.O.1    Pertseva, M.N.2
  • 155
    • 44349138039 scopus 로고    scopus 로고
    • Insulin signaling and FOXO regulate the overwintering diapause of the mosquito Culex pipiens
    • U.S.A.
    • Sim, C., and Denlinger, D. L. (2008) Insulin signaling and FOXO regulate the overwintering diapause of the mosquito Culex pipiens. Proc. Natl. Acad. Sci. U.S.A. 105, 6777-6781.
    • (2008) Proc. Natl. Acad. Sci , vol.105 , pp. 6777-6781
    • Sim, C.1    Denlinger, D.L.2
  • 156
    • 67249090418 scopus 로고    scopus 로고
    • A shut-down in expression of an insulin-like peptide, ILP-1, halts ovarian maturation during the overwintering diapause of the mosquito Culex pipiens
    • Sim, C., and Denlinger, D. L. (2009) A shut-down in expression of an insulin-like peptide, ILP-1, halts ovarian maturation during the overwintering diapause of the mosquito Culex pipiens. Insect Mol. Biol. 18, 325-332.
    • (2009) Insect Mol. Biol , vol.18 , pp. 325-332
    • Sim, C.1    Denlinger, D.L.2
  • 157
    • 84872573081 scopus 로고    scopus 로고
    • Juvenile hormone III suppresses forkhead of transcription factor in the fat body and reduces fat accumulation in the diapausing mosquito, Culex pipiens
    • Sim, C., and Denlinger, D. L. (2013) Juvenile hormone III suppresses forkhead of transcription factor in the fat body and reduces fat accumulation in the diapausing mosquito, Culex pipiens. Insect Mol. Biol. 22, 1-11.
    • (2013) Insect Mol. Biol , vol.22 , pp. 1-11
    • Sim, C.1    Denlinger, D.L.2
  • 158
    • 33750810558 scopus 로고    scopus 로고
    • Evolutionary trade-offbetween weapons and testes
    • U.S.A.
    • Simmons, L. W., and Emlen, D. J. (2006) Evolutionary trade-offbetween weapons and testes. Proc. Natl. Acad. Sci. U.S.A. 103, 16346-16351.
    • (2006) Proc. Natl. Acad. Sci , vol.103 , pp. 16346-16351
    • Simmons, L.W.1    Emlen, D.J.2
  • 160
    • 71649107200 scopus 로고    scopus 로고
    • A Drosophila insulin-like peptide promotes growth during nonfeeding states
    • Slaidina, M., Delanoue, R., Gronke, S., Partridge, L., and Leopold, P. (2009) A Drosophila insulin-like peptide promotes growth during nonfeeding states. Dev. Cell 17, 874-884.
    • (2009) Dev. Cell , vol.17 , pp. 874-884
    • Slaidina, M.1    Delanoue, R.2    Gronke, S.3    Partridge, L.4    Leopold, P.5
  • 161
    • 0034595797 scopus 로고    scopus 로고
    • A new secreted insect protein belonging to the immunoglobulin superfamily binds insulin and related peptides and inhibits their activities
    • Sloth Andersen, A., Hertz Hansen, P., Schaffer, L., and Kristensen, C. (2000) A new secreted insect protein belonging to the immunoglobulin superfamily binds insulin and related peptides and inhibits their activities. J. Biol. Chem. 275, 16948-16953.
    • (2000) J. Biol. Chem , vol.275 , pp. 16948-16953
    • Sloth Andersen, A.1    Hertz Hansen, P.2    Schaffer, L.3    Kristensen, C.4
  • 162
    • 84859723629 scopus 로고    scopus 로고
    • Insulin signaling as a mechanism underlying developmental plasticity: the role of FOXO in a nutritional polyphenism
    • Snell-Rood, E. C., and Moczek, A. P. (2012) Insulin signaling as a mechanism underlying developmental plasticity: the role of FOXO in a nutritional polyphenism. PLoS ONE 7:e34857.
    • (2012) PLoS ONE , vol.7
    • Snell-Rood, E.C.1    Moczek, A.P.2
  • 163
    • 84874345720 scopus 로고    scopus 로고
    • Insulin-producing cells in the Drosophila brain also express satiety-inducing cholecystokinin-like peptide, drosulfakinin
    • Soderberg, J. A., Carlsson, M. A., and Nassel, D. R. (2012) Insulin-producing cells in the Drosophila brain also express satiety-inducing cholecystokinin-like peptide, drosulfakinin. Front. Endocrinol. (Lausanne) 3:109.
    • (2012) Front. Endocrinol. (Lausanne) , vol.3 , pp. 109
    • Soderberg, J.A.1    Carlsson, M.A.2    Nassel, D.R.3
  • 164
    • 84867593226 scopus 로고    scopus 로고
    • Integration of taste and calorie sensing in Drosophila
    • Stafford, J. W., Lynd, K. M., Jung, A. Y., and Gordon, M. D. (2012) Integration of taste and calorie sensing in Drosophila. J. Neurosci. 32, 14767-14774.
    • (2012) J. Neurosci , vol.32 , pp. 14767-14774
    • Stafford, J.W.1    Lynd, K.M.2    Jung, A.Y.3    Gordon, M.D.4
  • 165
    • 2942516061 scopus 로고    scopus 로고
    • Relationship between firing activity of bombyxin-producing neurosecretory cells and hemolymph bombyxin titer in the silkworm Bombyx mori
    • Suenobu, A., Mizoguchi, A., and Ichikawa, T. (2004) Relationship between firing activity of bombyxin-producing neurosecretory cells and hemolymph bombyxin titer in the silkworm Bombyx mori. Gen. Comp. Endocrinol. 137, 219-226.
    • (2004) Gen. Comp. Endocrinol , vol.137 , pp. 219-226
    • Suenobu, A.1    Mizoguchi, A.2    Ichikawa, T.3
  • 166
    • 84861459244 scopus 로고    scopus 로고
    • FoxO inhibits juvenile hormone biosynthesis and vitellogenin production in the German cockroach
    • Suren-Castillo, S., Abrisqueta, M., and Maestro, J. L. (2012) FoxO inhibits juvenile hormone biosynthesis and vitellogenin production in the German cockroach. Insect Biochem. Mol. Biol. 42, 491-498.
    • (2012) Insect Biochem. Mol. Biol , vol.42 , pp. 491-498
    • Suren-Castillo, S.1    Abrisqueta, M.2    Maestro, J.L.3
  • 168
    • 9744271698 scopus 로고    scopus 로고
    • The neuroendocrine regulation of Drosophila aging
    • Tatar, M. (2004) The neuroendocrine regulation of Drosophila aging. Exp. Gerontol. 39, 1745-1750.
    • (2004) Exp. Gerontol , vol.39 , pp. 1745-1750
    • Tatar, M.1
  • 169
    • 0035062236 scopus 로고    scopus 로고
    • Slow aging during insect reproductive diapause: why butterflies, grasshoppers and flies are like worms
    • Tatar, M., and Yin, C. (2001) Slow aging during insect reproductive diapause: why butterflies, grasshoppers and flies are like worms. Exp. Gerontol. 36, 723-738.
    • (2001) Exp. Gerontol , vol.36 , pp. 723-738
    • Tatar, M.1    Yin, C.2
  • 170
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • Tatar, M., Kopelman, A., Epstein, D., Tu, M. P., Yin, C. M., and Garofalo, R. S. (2001) A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292, 107-110.
    • (2001) Science , vol.292 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.P.4    Yin, C.M.5    Garofalo, R.S.6
  • 171
    • 72449195397 scopus 로고    scopus 로고
    • Molecular mechanisms of metabolic regulation by insulin in Drosophila
    • Teleman, A. A. (2010) Molecular mechanisms of metabolic regulation by insulin in Drosophila. Biochem. J. 425, 13-26.
    • (2010) Biochem. J. , vol.425 , pp. 13-26
    • Teleman, A.A.1
  • 172
    • 18644367774 scopus 로고    scopus 로고
    • A microarray analysis of genes involved in relating egg production to nutritional intake in Drosophila melanogaster
    • Terashima, J., and Bownes, M. (2005) A microarray analysis of genes involved in relating egg production to nutritional intake in Drosophila melanogaster. Cell Death Differ. 12, 429-440.
    • (2005) Cell Death Differ , vol.12 , pp. 429-440
    • Terashima, J.1    Bownes, M.2
  • 173
    • 27644564868 scopus 로고    scopus 로고
    • Nutritional status affects 20-hydroxyecdysone concentration and progression of oogenesis in Drosophila melanogaster
    • Terashima, J., Takaki, K., Sakurai, S., and Bownes, M. (2005) Nutritional status affects 20-hydroxyecdysone concentration and progression of oogenesis in Drosophila melanogaster. J. Endocrinol. 187, 69-79.
    • (2005) J. Endocrinol , vol.187 , pp. 69-79
    • Terashima, J.1    Takaki, K.2    Sakurai, S.3    Bownes, M.4
  • 174
    • 84878998463 scopus 로고    scopus 로고
    • Control of germline stem cell self-renewal and differentiation in the Drosophila ovary: concerted actions of niche signals and intrinsic factors
    • Ting, X. (2013) Control of germline stem cell self-renewal and differentiation in the Drosophila ovary: concerted actions of niche signals and intrinsic factors. WIRE Dev. Biol. 2, 261-273.
    • (2013) WIRE Dev. Biol , vol.2 , pp. 261-273
    • Ting, X.1
  • 175
    • 0016515230 scopus 로고
    • Corpus allatum activity in vitro during ovarian maturation in the desert locust, Schistocerca gregaria
    • Tobe, S. S., and Pratt, G. E. (1975) Corpus allatum activity in vitro during ovarian maturation in the desert locust, Schistocerca gregaria. J. Exp. Biol. 62, 611-627.
    • (1975) J. Exp. Biol , vol.62 , pp. 611-627
    • Tobe, S.S.1    Pratt, G.E.2
  • 176
    • 58349117867 scopus 로고    scopus 로고
    • Endocrine regulation of aging and reproduction in Drosophila
    • Toivonen, J. M., and Partridge, L. (2009) Endocrine regulation of aging and reproduction in Drosophila. Mol. Cell. Endocrinol. 299, 39-50.
    • (2009) Mol. Cell. Endocrinol , vol.299 , pp. 39-50
    • Toivonen, J.M.1    Partridge, L.2
  • 177
    • 0034617897 scopus 로고    scopus 로고
    • Sperm competition games played by dimorphic male beetles: fertilization gains with equal mating access
    • Tomkins, J. L., and Simmons, L. W. (2000) Sperm competition games played by dimorphic male beetles: fertilization gains with equal mating access. Proc. Biol. Sci. 267, 1547-1553.
    • (2000) Proc. Biol. Sci , vol.267 , pp. 1547-1553
    • Tomkins, J.L.1    Simmons, L.W.2
  • 178
    • 0001039666 scopus 로고    scopus 로고
    • Impaired ovarian ecdysone synthesis of Drosophila melanogaster insulin receptor mutants
    • Tu, M. P., Yin, C. M., and Tatar, M. (2002) Impaired ovarian ecdysone synthesis of Drosophila melanogaster insulin receptor mutants. Aging Cell 1, 158-160.
    • (2002) Aging Cell , vol.1 , pp. 158-160
    • Tu, M.P.1    Yin, C.M.2    Tatar, M.3
  • 179
    • 20344370948 scopus 로고    scopus 로고
    • Mutations in insulin signaling pathway alter juvenile hormone synthesis in Drosophila melanogaster
    • Tu, M. P., Yin, C. M., and Tatar, M. (2005) Mutations in insulin signaling pathway alter juvenile hormone synthesis in Drosophila melanogaster. Gen. Comp. Endocrinol. 142, 347-356.
    • (2005) Gen. Comp. Endocrinol , vol.142 , pp. 347-356
    • Tu, M.P.1    Yin, C.M.2    Tatar, M.3
  • 180
    • 58149510104 scopus 로고    scopus 로고
    • Insect vitellogenin/lipophorin receptors: molecular structures, role in oogenesis, and regulatory mechanisms
    • Tufail, M., and Takeda, M. (2009) Insect vitellogenin/lipophorin receptors: molecular structures, role in oogenesis, and regulatory mechanisms. J. Insect Physiol 55, 87-103.
    • (2009) J. Insect Physiol , vol.55 , pp. 87-103
    • Tufail, M.1    Takeda, M.2
  • 181
    • 67650266694 scopus 로고    scopus 로고
    • Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila
    • Ueishi, S., Shimizu, H., and Inoue, H. (2009) Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila. Cell Struct. Funct. 34, 61-69.
    • (2009) Cell Struct. Funct , vol.34 , pp. 61-69
    • Ueishi, S.1    Shimizu, H.2    Inoue, H.3
  • 182
    • 0035131422 scopus 로고    scopus 로고
    • Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster
    • Vanden Broeck, J. (2001) Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster. Peptides 22, 241-254.
    • (2001) Peptides , vol.22 , pp. 241-254
    • Vanden Broeck, J.1
  • 183
    • 77950461285 scopus 로고    scopus 로고
    • What the loss of the hormone neuroparsin in the melanogaster subgroup of Drosophila can tell us about its function
    • Veenstra, J. A. (2010) What the loss of the hormone neuroparsin in the melanogaster subgroup of Drosophila can tell us about its function. Insect Biochem. Mol. Biol. 40, 354-361.
    • (2010) Insect Biochem. Mol. Biol , vol.40 , pp. 354-361
    • Veenstra, J.A.1
  • 184
    • 34248187474 scopus 로고    scopus 로고
    • Polyphenism in insects and the juvenile hormone
    • Verma, K. K. (2007) Polyphenism in insects and the juvenile hormone. J. Biosci. 32, 415-420.
    • (2007) J. Biosci. , vol.32 , pp. 415-420
    • Verma, K.K.1
  • 185
    • 79957795471 scopus 로고    scopus 로고
    • Nutritional sensitivity of fifth instar prothoracic glands in the tobacco hornworm, Manduca sexta
    • Walsh, A. L., and Smith, W. A. (2011) Nutritional sensitivity of fifth instar prothoracic glands in the tobacco hornworm, Manduca sexta. J. Insect Physiol 57, 809-818.
    • (2011) J. Insect Physiol , vol.57 , pp. 809-818
    • Walsh, A.L.1    Smith, W.A.2
  • 186
    • 80051716895 scopus 로고    scopus 로고
    • Regulation of adult stem cell behavior by nutrient signaling
    • Wang, L., McLeod, C. J., and Jones, D. L. (2011) Regulation of adult stem cell behavior by nutrient signaling. Cell Cycle 10, 2628-2634.
    • (2011) Cell Cycle , vol.10 , pp. 2628-2634
    • Wang, L.1    McLeod, C.J.2    Jones, D.L.3
  • 187
    • 77956343172 scopus 로고    scopus 로고
    • Two insulin-like peptide family members from the mosquito Aedes aegypti exhibit differential biological and receptor binding activities
    • Wen, Z., Gulia, M., Clark, K. D., Dhara, A., Crim, J. W., Strand, M. R., et al. (2010) Two insulin-like peptide family members from the mosquito Aedes aegypti exhibit differential biological and receptor binding activities. Mol. Cell Endocrinol. 328, 47-55.
    • (2010) Mol. Cell Endocrinol , vol.328 , pp. 47-55
    • Wen, Z.1    Gulia, M.2    Clark, K.D.3    Dhara, A.4    Crim, J.W.5    Strand, M.R.6
  • 188
    • 70149101855 scopus 로고    scopus 로고
    • The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway
    • Werz, C., Kohler, K., Hafen, E., and Stocker, H. (2009) The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway. PLoS Genet. 5:e1000596.
    • (2009) PLoS Genet , vol.5
    • Werz, C.1    Kohler, K.2    Hafen, E.3    Stocker, H.4
  • 189
    • 33750431066 scopus 로고    scopus 로고
    • Expression of insulin pathway genes during the period of caste determination in the honey bee, Apis mellifera
    • Wheeler, D. E., Buck, N., and Evans, J. D. (2006) Expression of insulin pathway genes during the period of caste determination in the honey bee, Apis mellifera. Insect Mol. Biol. 15, 597-602.
    • (2006) Insect Mol. Biol , vol.15 , pp. 597-602
    • Wheeler, D.E.1    Buck, N.2    Evans, J.D.3
  • 190
    • 0031918624 scopus 로고    scopus 로고
    • The IRS-signalling system: a network of docking proteins that mediate insulin action
    • White, M. F. (1998) The IRS-signalling system: a network of docking proteins that mediate insulin action. Mol. Cell. Biochem. 182, 3-11.
    • (1998) Mol. Cell. Biochem , vol.182 , pp. 3-11
    • White, M.F.1
  • 191
    • 79551492162 scopus 로고    scopus 로고
    • Insulin receptor substrate influences female caste development in honeybees
    • Wolschin, F., Mutti, N. S., and Amdam, G. V. (2011) Insulin receptor substrate influences female caste development in honeybees. Biol. Lett. 7, 112-115.
    • (2011) Biol. Lett , vol.7 , pp. 112-115
    • Wolschin, F.1    Mutti, N.S.2    Amdam, G.V.3
  • 192
    • 30844437476 scopus 로고    scopus 로고
    • Signaling and function of insulin-like peptides in insects
    • Wu, Q., and Brown, M. R. (2006) Signaling and function of insulin-like peptides in insects. Annu. Rev. Entomol. 51, 1-24.
    • (2006) Annu. Rev. Entomol , vol.51 , pp. 1-24
    • Wu, Q.1    Brown, M.R.2
  • 193
    • 27744546414 scopus 로고    scopus 로고
    • Regulation of aversion to noxious food by Drosophila neuropeptide Y- and insulin-like systems
    • Wu, Q., Zhao, Z., and Shen, P. (2005) Regulation of aversion to noxious food by Drosophila neuropeptide Y- and insulin-like systems. Nat. Neurosci. 8, 1350-1355.
    • (2005) Nat. Neurosci , vol.8 , pp. 1350-1355
    • Wu, Q.1    Zhao, Z.2    Shen, P.3
  • 194
    • 0030002820 scopus 로고    scopus 로고
    • The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis
    • Yenush, L., Fernandez, R., Myers, M. G., Grammer, T. C., Sun, X. J., Blenis, J., et al. (1996) The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis. Mol. Cell. Biol. 16, 2509-2517.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 2509-2517
    • Yenush, L.1    Fernandez, R.2    Myers, M.G.3    Grammer, T.C.4    Sun, X.J.5    Blenis, J.6
  • 195
    • 84863923115 scopus 로고    scopus 로고
    • Insulin signalling in mushroom body neurons regulates feeding behaviour in Drosophila larvae
    • Zhao, X. L., and Campos, A. R. (2012) Insulin signalling in mushroom body neurons regulates feeding behaviour in Drosophila larvae. J. Exp. Biol. 215, 2696-2702.
    • (2012) J. Exp. Biol , vol.215
    • Zhao, X.L.1    Campos, A.R.2
  • 196
    • 11144221344 scopus 로고    scopus 로고
    • Utilization of pre-existing energy stores of female Aedes aegypti mosquitoes during the first gonotrophic cycle
    • Zhou, G., Pennington, J. E., and Wells, M. A. (2004) Utilization of pre-existing energy stores of female Aedes aegypti mosquitoes during the first gonotrophic cycle. Insect Biochem. Mol. Biol. 34, 919-925.
    • (2004) Insect Biochem. Mol. Biol , vol.34 , pp. 919-925
    • Zhou, G.1    Pennington, J.E.2    Wells, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.