Relations of arterial stiffness and endothelial function to brain aging in the community

Neurology

Volumn 81, Issue 11, 2013, Pages 984-991

  Tsao, Connie W ^a,g   Seshadri, Sudha ^b,g   Beiser, Alexa S ^b,c,g   Westwood, Andrew J ^b   DeCarli, Charles ^e   Au, Rhoda ^b,g   Himali, Jayandra J ^b,c   Hamburg, Naomi M ^b   Vita, Joseph A ^b   Levy, Daniel ^b,f,g   Larson, Martin G ^c,d,g   Benjamin, Emelia J ^b,g   Wolf, Philip A ^b,g   Vasan, Ramachandran S ^b,g   Mitchell, Gary F ^h  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b Department of Neurology ^*  (United States)

^c Loma Linda University   (United States)

^d Boston University   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^g FRAMINGHAM HEART STUDY   (United States)

^h CARDIOVASCULAR ENGINEERING INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTERIAL PRESSURE; ARTERIAL STIFFNESS; ARTICLE; BRAIN BLOOD VESSEL; BRAIN INFARCTION; BRAIN SIZE; CAROTID FEMORAL PULSE WAVE VELOCITY; CENTRAL PULSE PRESSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; PRIORITY JOURNAL; PULSE PRESSURE; PULSE WAVE; VASCULAR ENDOTHELIUM; WHITE MATTER;

AGED; AGING; BLOOD PRESSURE; BRACHIAL ARTERY; BRAIN; COGNITION; COHORT STUDIES; ENDOTHELIUM; FEMALE; HEMODYNAMICS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MANOMETRY; MIDDLE AGED; NERVE FIBERS, MYELINATED; NEUROPSYCHOLOGICAL TESTS; RESIDENCE CHARACTERISTICS; RETROSPECTIVE STUDIES; ULTRASONOGRAPHY, DOPPLER, PULSED; VASCULAR STIFFNESS;

EID: 84884555186     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3182a43e1c     Document Type: Article

References (43)

1. Lee HY, Oh BH. Aging and arterial stiffness. Circ J 2010; 74:2257-2262.
2. Mitchell GF, Guo CY, Benjamin EJ, et al. Cross-sectional correlates of increased aortic stiffness in the community: the Framingham Heart Study. Circulation 2007;115: 2628-2636.
3. Mitchell GF. Effects of central arterial aging on the structure and function of the peripheral vasculature: implications for end-organ damage. J Appl Physiol 2008;105: 1652-1660.
4. Mattace-Raso FU, van der Cammen TJ, Hofman A, et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation 2006;113:657-663.
5. Mitchell GF, Hwang SJ, Vasan RS, et al. Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation 2010;121:505-511.
6. Sutton-Tyrrell K, Najjar SS, Boudreau RM, et al. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation 2005;111:3384-3390.
7. Willum-Hansen T, Staessen JA, Torp-Pedersen C, et al. Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population. Circulation 2006;113:664-670.
8. Au R, Massaro JM, Wolf PA, et al. Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study. Arch Neurol 2006;63:246-250.
9. Kalaria RN, Akinyemi R, Ihara M. Does vascular pathology contribute to Alzheimer changes? J Neurol Sci 2012;322: 141-147.
10. Mitchell GF, van Buchem MA, Sigurdsson S, et al. Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility-Reykjavik Study. Brain 2011;134:3398-3407.
11. Verma S, Buchanan MR, Anderson TJ. Endothelial function testing as a biomarker of vascular disease. Circulation 2003;108:2054-2059.
12. Yeboah J, Crouse JR, Hsu FC, Burke GL, Herrington DM. Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation 2007;115:2390-2397.
13. Hoth KF, Tate DF, Poppas A, et al. Endothelial function and white matter hyperintensities in older adults with cardiovascular disease. Stroke 2007;38:308-312.
14. Gonzales MM, Tarumi T, Tanaka H, et al. Functional imaging of working memory and peripheral endothelial function in middle-aged adults. Brain Cogn 2010;73:146-151.
15. Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP. An investigation of coronary heart disease in families: the Framingham Offspring Study. Am J Epidemiol 1979;110:281-290.
16. Kelly R, Fitchett D. Noninvasive determination of aortic input impedance and external left ventricular power output: a validation and repeatability study of a new technique. J Am Coll Cardiol 1992;20:952-963.
17. Mitchell GF, Parise H, Benjamin EJ, et al. Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension 2004;43:1239-1245.
18. Mitchell GF, Parise H, Vita JA, et al. Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension 2004;44:134-139.
19. DeCarli C, Maisog J, Murphy DG, Teichberg D, Rapoport SI, Horwitz B. Method for quantification of brain, ventricular, and subarachnoid CSF volumes from MR images. J Comput Assist Tomogr 1992;16:274-284.
20. DeCarli C, Massaro J, Harvey D, et al. Measures of brain morphology and infarction in the Framingham Heart Study: establishing what is normal. Neurobiol Aging 2005;26:491-510.
21. Au R, Seshadri S, Wolf P, et al. New norms for a new generation: cognitive performance in the Framingham Offspring Cohort. Exp Aging Res 2004;30:333-358.
22. Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study. Curr Alzheimer Res 2007;4:111-116.
23. Baumbach GL. Effects of increased pulse pressure on cerebral arterioles. Hypertension 1996;27:159-167.
24. Nigam A, Mitchell GF, Lambert J, Tardif JC. Relation between conduit vessel stiffness (assessed by tonometry) and endothelial function (assessed by flow-mediated dilatation) in patients with and without coronary heart disease. Am J Cardiol 2003;92:395-399.
25. Fazekas F, Kleinert R, Offenbacher H, et al. Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology 1993;43:1683-1689.
26. Bonyhay I, Jokkel G, Kollai M. Relation between baroreflex sensitivity and carotid artery elasticity in healthy humans. Am J Physiol 1996;271:H1139-H1144.
27. Havlik RJ, Foley DJ, Sayer B, Masaki K, White L, Launer LJ. Variability in midlife systolic blood pressure is related to late-life brain white matter lesions: the Honolulu-Asia Aging Study. Stroke 2002;33:26-30.
28. Ballard C, O'Brien J, Barber B, et al. Neurocardiovascular instability, hypotensive episodes, and MRI lesions in neurodegenerative dementia. Ann NY Acad Sci 2000;903: 442-445.
29. Shah NS, Vidal JS, Masaki K, et al. Midlife blood pressure, plasma beta-amyloid, and the risk for Alzheimer disease: the Honolulu Asia Aging Study. Hypertension 2012;59:780-786.
30. Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery WR. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA 1997;277:813-817.
31. Coutinho T, Turner ST, Kullo IJ. Aortic pulse wave velocity is associated with measures of subclinical target organ damage. JACC Cardiovasc Imaging 2011;4:754-761.
32. Henskens LH, Kroon AA, van Oostenbrugge RJ, et al. Increased aortic pulse wave velocity is associated with silent cerebral small-vessel disease in hypertensive patients. Hypertension 2008;52:1120-1126.
33. Poels MM, Zaccai K, Verwoert GC, et al. Arterial stiffness and cerebral small vessel disease: the Rotterdam Scan Study. Stroke 2012;43:2637-2642.
34. Elias MF, Robbins MA, Budge MM, Abhayaratna WP, Dore GA, Elias PK. Arterial pulse wave velocity and cognition with advancing age. Hypertension 2009;53:668-673.
35. Kearney-Schwartz A, Rossignol P, Bracard S, et al. Vascular structure and function is correlated to cognitive performance and white matter hyperintensities in older hypertensive patients with subjective memory complaints. Stroke 2009; 40:1229-1236.
36. Waldstein SR, Rice SC, Thayer JF, Najjar SS, Scuteri A, Zonderman AB. Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore Longitudinal Study of Aging. Hypertension 2008;51:99-104.
37. Mitchell GF, Vita JA, Larson MG, et al. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation 2005;112:3722-3728.
38. Thanassoulis G, Lyass A, Benjamin EJ, et al. Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study. Circulation 2012;125:2836-2843.
39. Parikh NI, Keyes MJ, Larson MG, et al. Visceral and subcutaneous adiposity and brachial artery vasodilator function. Obesity 2009;17:2054-2059.
40. Smith PJ, Blumenthal JA, Babyak MA, Hinderliter A, Sherwood A. Association of vascular health and neurocognitive performance in overweight adults with high blood pressure. J Clin Exp Neuropsychol 2011;33: 559-566.
41. Smith PJ, Blumenthal JA, Babyak MA, et al. Cerebrovascular risk factors, vascular disease, and neuropsychological outcomes in adults with major depression. Psychosom Med 2007;69:578-586.
42. Girouard H, Iadecola C. Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J Appl Physiol 2006;100:328-335.
43. Gorelick PB, Scuteri A, Black SE, et al. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2011;42:2672-2713.