Fast, simultaneous quantification of three novel cardiac drugs in human urine by MEPS-UHPLC-MS/MS for therapeutic drug monitoring

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 938, Issue , 2013, Pages 86-95

  Magiera, Sylwia ^a  

^a SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Drugs; Liquid chromatography; Mass spectrometry; Method validation; Microextraction by packed sorbent

Indexed keywords

CHROMATOGRAPHIC SEPARATIONS; DRUGS; LOWER LIMIT OF QUANTIFICATIONS; METHOD VALIDATIONS; MICRO-EXTRACTION BY PACKED SORBENTS; MULTIPLE REACTION MONITORING; THERAPEUTIC DRUG MONITORING; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;

BODY FLUIDS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT MONITORING; SORPTION;

DRUG PRODUCTS;

ACETONITRILE; ALISKIREN; CARVEDILOL; PRASUGREL; RIVAROXABAN; SORBENT;

ACCURACY; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG MONITORING; DRUG SCREENING; DRUG URINE LEVEL; ELECTRONICS; ELECTROSPRAY; FLOW RATE; HUMAN; LIMIT OF QUANTITATION; MICROEXTRACTION WITH PACKED SORBENT; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; SOLID PHASE MICROEXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINE;

DRUGS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHOD VALIDATION; MICROEXTRACTION BY PACKED SORBENT;

CARDIOVASCULAR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG MONITORING; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84884538916     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.09.001     Document Type: Article

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