Effect of inhaled corticosteroids on long-term growth in pediatric patients with asthma and allergic rhinitis

Annals of Pharmacotherapy

Volumn 47, Issue 9, 2013, Pages 1175-1181

  Hoover, Rebecca M ^a   Erramouspe, John ^a   Bell, Edward A ^b   Cleveland, Kevin W ^a  

^a IDAHO STATE UNIVERSITY   (United States)

^b DRAKE UNIVERSITY   (United States)

Author keywords

Inhaled corticosteroids; Linear growth; Long term height

Indexed keywords

BECLOMETASONE; BUDESONIDE; CICLESONIDE; CORTICOSTEROID; FLUNISOLIDE; FLUTICASONE; FLUTICASONE FUROATE; FLUTICASONE PROPIONATE; MOMETASONE FUROATE; NEDOCROMIL; PLACEBO; TRIAMCINOLONE;

ALLERGIC RHINITIS; ARTICLE; BODY HEIGHT; CHILD GROWTH; CHILDHOOD MORTALITY; CHRONIC DRUG ADMINISTRATION; CORTICOSTEROID THERAPY; FOLLOW UP; FOOD AND DRUG ADMINISTRATION; GROWTH RATE; HUMAN; LONG TERM CARE; LONG TERM EXPOSURE; MODERATE PERSISTENT ASTHMA; MORBIDITY; OUTCOME ASSESSMENT; PERENNIAL RHINITIS; PRIORITY JOURNAL; TREATMENT DURATION;

INHALED CORTICOSTEROIDS; LINEAR GROWTH; LONG-TERM HEIGHT;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ASTHMA; BODY HEIGHT; CHILD; HUMANS; RHINITIS, ALLERGIC, PERENNIAL;

EID: 84884487839     PISSN: 10600280     EISSN: 15426270     Source Type: Journal    
DOI: 10.1177/1060028013503125     Document Type: Article

References (37)

1. Akinbami LJ, Moorman JE, Liu X. Asthma prevalence, health care use, and mortality: United States, 2005-2009. National Health Statistics reports; no 32. Hyattsville, MD: National Center for Health Statistics. 2011:1-16.
2. Suissa S, Ernst P, Benayoun S, Baltzan M, Cai B. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med 2000;343:332-6.
3. Donahue JG, Weiss ST, Livingston JM, et al. Inhaled steroids and the risk of hospitalization for asthma. JAMA 1997;277:887-91.
4. National Heart, Lung, and Blood Institute. National Asthma Education and Prevention Program. Expert Panel Report 3: guidelines for the diagnosis and management of asthma. 2007;120(suppl):S94-138. doi: 10.1016/j.jaci.2007.09.029
5. Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA). Eur Respir J 2008;31:143-78.
6. US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research. Orally inhaled and intranasal corticosteroids: evaluation of the effects on growth in children. Guidance for Industry. 2007;1-14. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm071968.pdf (accessed 2012 Nov).
7. Crompton G. A brief history of inhaled asthma therapy over the last fifty years. Prim Care Respir J 2006;15:326-31.
8. Baxter-Jones AD, Helms PJ, Robins S. Inhaled corticosteroid reduces bone turnover but not short-term growth in early childhood Am J Respir Crit Care Med 1999;159:A909.
9. Visser MJ, van Aalderen WM, Elliott BM, Odink RJ, Brand PL. Short-term growth in asthmatic children using fluticasone propionate. Chest 1998;113:584-6.
10. Agertoft L, Pedersen S. Effects of long term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med 1994;88:373-81.
11. Doull IJ, Campbell MJ, Holgate ST. Duration of growth suppressive effects of regular inhaled corticosteroids. Arch Dis Child 1998;78:172-3.
12. Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group. N Engl J Med 2000;343:1054-63.
13. Kelly HW, Sternberg AL, Lescher R, et al.; CAMP Research Group. Effect of inhaled glucocorticoids in childhood on adult height. N Engl J Med 2012;367:904-12.
14. Becker AB, Kuznetsova O, Vermeulen J, et al.; Pediatric Montelukast Linear Growth Study Group. Linear growth in prepubertal asthmatic children treated with montelukast, beclomethasone, or placebo: a 56-week randomized doubleblind study. Ann Allergy Asthma Immunol 2006;96:800-7.
15. Bensch GW, Greos LS, Gawchik S, Kpamegan E, Newman KB. Linear growth and bone maturation are unaffected by 1 year of therapy with in-haled flunisolide hydrofluoroalkane in prepubescent children with mild persistent asthma: a randomized, double-blind, placebo-controlled trial. Ann Allergy Asthma Immunol 2011;107:323-9.
16. Skoner DP, Maspero J, Banerji D; Ciclesonide Pediatric Growth Study Group. Assessment of the long-term safety of inhaled ciclesonide on growth in children with asthma. Pediatrics 2008;121:e1-14.
17. Allen DB, Bronsky EA, LaForce CF, et al. Growth in asthmatic children treated with fluticasone propionate. Fluticasone Propionate Asthma Study Group. J Pediatr 1998;132:472-7.
18. Skoner DP, Meltzer EO, Milgrom H, et al. Effects of inhaled mometasone furoate on growth velocity and adrenal function: a placebo-controlled trial in children 4-9 years old with mild persistent asthma. J Asthma 2011;48:848-59.
19. Package insert. Asmanex Twisthaler (mometasone furoate inhalation powder. Kenilworth, NJ: Schering Corporation, September 2010.
20. Guilbert TW, Mauger DT, Allen DB, et al.; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. J Allergy Clin Immunol 2011;128:956-63. e1-7.
21. Skoner DP, Rachelefsky GS, Meltzer EO, et al. Detection of growth suppression in children during treatment with intranasal beclomethasone dipropionate. Pediatrics 2000; 105:E23.
22. Murphy K, Uryniak T, Simpson B, O'Dowd L. Growth velocity in children with perennial allergic rhinitis treated with budesonide aqueous nasal spray. Ann Allergy Asthma Immunol 2006;96:723-30.
23. Allen DB, Meltzer EO, Lemanske RF, et al. No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one year. Allergy Asthma Proc 2002; 23:407-13.
24. Schenkel EJ, Skoner DP, Bronsky EA, et al. Absence of growth retardation in children with perennial allergic rhinitis after one year of treatment with mometasone furoate aqueous nasal spray. Pediatrics 2000;105:E22.
25. Pedersen S. Do inhaled corticosteroids inhibit growth in children? Am J Respir Crit Care Med 2001;164:521-35.
26. Pedersen S. Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials. Drug Saf 2006;29:599-612.
27. Balfour-Lynn L. Effect of asthma on growth and puberty. Pediatrician 1987;14:237-41.
28. Doull IJ. The effect of asthma and its treatment on growth. Arch Dis Child 2004;89:60-3.
29. Fergusson AC, Murray AB, Tze WJ. Short stature and delayed skeletal maturation in children with allergic disease. J Allergy Clin Immunol 1982;69:461-5.
30. Doull IJ, Freezer NJ, Holgate ST. Growth of prepubertal children with mild asthma treated with inhaled beclomethasone dipropionate. Am J Respir Crit Care Med 1995;151:1715-9.
31. Russell G. Asthma and growth. Arch Dis Child 1993;69:695-8.
32. Kelly HW. Comparison of inhaled corticosteroids: an update. Ann Pharmacother 2009;43:519-27. doi: 10.1345/aph.1L456
33. Zar HJ, Weinberg EG, Binns HJ, Gallie F, Mann MD. Lung deposition of aerosol-a comparison of different spacers. Arch Dis Child 2000;82: 495-8.
34. Takizawa H. Recent development of drug delivery systems for the treatment of asthma and related disorders. Recent Pat Inflamm Allergy Drug Discov 2009;3:232-9.
35. Sastre J, Mosges R. Local and systemic safety of intranasal corticosteroids. J Investig Allergol Clin Immunol 2012;22:1-12.
36. Martinez FD, Chinchilli VM, Morgan WJ, et al. Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, doubleblind, placebo-controlled trial. Lancet 2011;377:650-7.
37. Boushey HA, Sorkness CA, King TS, et al. Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma. N Engl J Med 2007;356:2040-52.