Early seizure onset and dysplastic lesion extent independently disrupt cognitive networks

Neurology

Volumn 81, Issue 8, 2013, Pages 745-751

  Korman, Brandon ^a   Krsek, Pavel ^b   Duchowny, Michael ^a   Maton, Bruno ^c   Pacheco Jacome, Esperanza ^a   Rey, Gustavo ^a  

^a MIAMI CHILDREN'S HOSPITAL   (United States)

^b CHARLES UNIVERSITY   (Czech Republic)

^c SENTARA HEART HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHILD; COGNITION; COGNITIVE DEFECT; CORTICAL DYSPLASIA; DYSPLASIA; FEMALE; HISTOPATHOLOGY; HUMAN; INTELLIGENCE QUOTIENT; INTRACTABLE EPILEPSY; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; ONSET AGE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SURGICAL PATIENT;

ADOLESCENT; CEREBRAL CORTEX; CHILD; CHILD, PRESCHOOL; COGNITION; COGNITION DISORDERS; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MALFORMATIONS OF CORTICAL DEVELOPMENT; NERVE NET; SEIZURES; YOUNG ADULT;

EID: 84884486087     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3182a1aa2a     Document Type: Article

References (39)

1. Besag FM. Cognitive and behavioral outcomes of epileptic syndromes: implications for education and clinical practice. Epilepsia 2006;47:119-125.
2. Oostrom K, Smeeets-Schouten A, Kruitwagen C, et al. Not only a matter of epilepsy: early problems of cognition and behavior in children with epilepsy only-a prospective, longitudinal, controlled study starting at diagnosis. Pediatrics 2003;112:1338-1344.
3. Smith ML, Elliott I, Lach L. Cognitive, psychosocial, and family function one year after pediatric epilepsy surgery. Epilepsia 2004;45:650-660.
4. Trimble MR. Cognitive hazards of seizure disorders. Epilepsia 1988;29(suppl 1):S19-S23.
5. Krsek P, Matan B, Jayakar P, et al. Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcome. Neurology 2009;72:217-223.
6. Lortie A, Plouin P, Chiron C, et al. Characteristics of epilepsy in focal cortical dysplasia in infancy. Epilepsy Res 2002;51:133-145.
7. Lucas M, Lenck-Santini P, Holmes G, Scott R. Impaired cognition in rats with cortical dysplasia: additional impact of early-life seizures. Brain 2011;134:1684-1693.
8. Klein B, Levin B, Duchowny M, et al. Cognitive outcome of children with epilepsy and malformations of cortical development. Neurology 2000;55:230-235.
9. Libenson MH. Practical Approach to Electroencephalography. Philadelphia: Saunders Elsevier; 2010.
10. Krsek P, Maton B, Korman B, et al. Different features of histopathological subtypes of pediatric focal cortical dysplasia. Ann Neurol 2008;63:758-769.
11. Mischel PS, Nguyen LP, Vinters HV. Cerebral cortical dysplasia associated with pediatric epilepsy. Review of neuropathological features and a proposal for a grading system. J Neuropathol Exp Neurol 1995;54:137-153.
12. Palmini A, Najm I, Avanzini G, et al. Terminology and classification of the cortical dysplasias. Neurology 2004;62: S2-S8.
13. Blumcke I, Thom M, Aronica E, et al. The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission. Epilepsia 2011;52: 158-174.
14. Ellis SJ, Ellis PJ, Marshall E, et al. Is forced dextrality an explanation for the fall in the prevalence of sinistrality with age? A study in northern England. J Epidemiol Community Health 1998;52:41-44.
15. Hermann B, Seidenberg M, Bell B, et al. The neurodevelopmental impact of childhood-onset temporal lobe epilepsy on brain structure and function. Epilepsia 2002;43: 1062-1071.
16. Bourgeois BF, Prensky AL, Palkes HS, et al. Intelligence in epilepsy: a prospective study in children. Ann Neurol 1983;14:438-444.
17. Duchowny M. Clinical, functional, and neurophysiologic assessment of dysplastic cortical networks: implications for cortical functioning and surgical management. Epilepsia 2009;50(suppl 9):19-27.
18. Vitali P, Minati L, D'Incerti L, et al. Functional MRI in malformations of cortical development: activation of dysplastic tissue and functional reorganization. J Neuroimaging 2008;18:296-305.
19. Janszky J, Ebner A, Kruse B, et al. Functional organization of the brain with malformations of cortical development. Ann Neurol 2003;53:759-767.
20. Guimaraes C, Bonilha L, Franzon R, et al. Distribution of regional gray matter abnormalities in a pediatric population with temporal lobe epilepsy and correlation with neuropsychological performance. Epilepsy Behav 2007;11:558-566.
21. Malmgren K, Olsson I, Engman E, et al. Seizure outcome after resective epilepsy surgery in patients with low IQ. Brain 2008;131:535-542.
22. Gleissner U, Clusmann H, Sassen R, et al. Postsurgical outcome in pediatric patients with intellectual disabilities, subaverage intelligence, and average-range intelligence. Epilepsia 2006;47:406-414.
23. Korman B, Bernal B, Duchowny M, et al. Atypical propositional language organization in prenatal and earlyacquired temporal lobe lesions. J Child Neurol 2011;25: 985-993.
24. Nolan MA, Redoblado MA, Lah S, et al. Intelligence in childhood epilepsy syndromes. Epilepsy Res 2003;53: 139-150.
25. Cormack F, Cross JH, Isaacs E, et al. The development of intellectual abilities in pediatric temporal lobe epilepsy. Epilepsia 2007;48:201-204.
26. Hermann B, Dabbs K, Becker T, et al. Brain development in children with new onset epilepsy: a prospective controlled cohort investigation. Epilepsia 2010;51:2038-2046.
27. Filippini M, Boni A, Dazzani G, et al. Neuropsychological findings: myoclonic astatic epilepsy (MAE) and Lennox-Gastaut syndrome (LGS). Epilepsia 2006;47(suppl 2):56-59.
28. Widdess-Walsh P, Kellinghaus C, Jeha L, et al. Electro-clinical and imaging characteristics of focal cortical dysplasia: correlation with pathological subtypes. Epilepsy Res 2005;67:25-33.
29. Kakita A, Kameyama S, Hayashi S, et al. Pathologic features of dysplasia and accompanying alterations observed in surgical specimens from patients with intractable epilepsy. J Child Neurol 2005;20:341-350.
30. Chassoux F, Devaux B, Landre E, et al. Stereoelectroencephalography in focal cortical dysplasia: a 3D approach to delineating the dysplastic cortex. Brain 2000;123:1733-1751.
31. Blumcke I. Neuropathology of focal epilepsies: a critical review. Epilepsy Behav 2009;15:34-39.
32. Byars A, deGrauw T, Johnson C, et al. The association of MRI findings and neuropsychological functioning after the first recognized seizure. Epilepsia 2007;48:1067-1074.
33. Fastenau PS, Johnson CS, Perkins SM, et al. Neuropsychological status at seizure onset in children. Neurology 2009;73: 526-534.
34. Fountas KN, King DW, Meador KJ, et al. Epilepsy in cortical dysplasia: factors affecting surgical outcome. Stereotact Funct Neurosurg 2004;82:26-30.
35. Hader W, Mackay M, Otsubo H, et al. Cortical dysplastic lesions in children with intractable epilepsy: role of complete resection. J Neurosurg 2004;100: 110-117.
36. Raybaud C, Shroff M, Rutka J. Imaging surgical epilepsy in children. Childs Nerv Syst 2006;22:786-809.
37. Cohen-Gadol A, Ozduman K, Bronen R, et al. Long-term outcome after epilepsy surgery for focal cortical dysplasia. J Neurosurg 2004;101:55-65.
38. Aldenkamp A, Alpherts W, Blennow G, et al. Withdrawal of antiepileptic medication in children-effects on cognitive function: the Multicenter Holmfrid Study. Neurology 1993;43:41-50.
39. Olney JW, Wozniak DF, Jevtovic-Todorovic V, et al. Drug-induced apoptotic neurodegeneration in the developing brain. Brain Pathol 2002;12:488-498.