Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia

Clinical Gastroenterology and Hepatology

Volumn 11, Issue 10, 2013, Pages 1313-1318

  Lidgard, Graham P ^a   Domanico, Michael J ^a   Bruinsma, Janelle J ^a   Light, James ^a   Gagrat, Zubin D ^a   Oldham Haltom, Rebecca L ^a   Fourrier, Keith D ^a   Allawi, Hatim ^a   Yab, Tracy C ^b   Taylor, William R ^b   Simonson, Julie A ^b   Devens, Mary ^b   Heigh, Russell I ^c   Ahlquist, David A ^b   Berger, Barry M ^a  

^a Exact Sciences Corporation   (United States)

^b MAYO CLINIC   (United States)

^c MAYO CLINIC   (United States)

Author keywords

BMP3; Colon Cancer; Early Detection; NDRG4; QuARTS

Indexed keywords

BETA ACTIN; HEMOGLOBIN; OSTEOGENIN;

ADULT; ADVANCED CANCER; AGED; ANALYTICAL EQUIPMENT; ARTICLE; CANCER SCREENING; CANCER STAGING; CASE CONTROL STUDY; COLONOSCOPY; COLORECTAL POLYP; COLORECTAL TUMOR; COMPUTER SIMULATION; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FECES; FECES ANALYSIS; FEMALE; GASTROINTESTINAL DYSPLASIA; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; RECTUM ADENOMA; SENSITIVITY AND SPECIFICITY; STOOL DNA ASSAY;

AA; ADVANCED ADENOMA; BMP3; COLON CANCER; COLORECTAL CANCER; CRC; EARLY DETECTION; FECAL IMMUNOCHEMICAL TEST; FIT; HB; HEMOGLOBIN; HGD; HIGH-GRADE DYSPLASIA; NDRG4; QUANTITATIVE ALLELE-SPECIFIC REAL-TIME TARGET AND SIGNAL AMPLIFICATION; QUARTS; SDNA; SESSILE SERRATED ADENOMA ≥1-CM SIZE; SSA; STOOL DNA;

ADULT; AGED; AGED, 80 AND OVER; AUTOMATION, LABORATORY; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; DNA; FECES; FEMALE; HEMOGLOBINS; HUMANS; MALE; MIDDLE AGED; MOLECULAR DIAGNOSTIC TECHNIQUES; SENSITIVITY AND SPECIFICITY; SINGLE-BLIND METHOD; TUMOR MARKERS, BIOLOGICAL;

EID: 84884356620     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2013.04.023     Document Type: Article

References (16)

1. Berger B.M., Ahlquist D.A. Stool DNA screening for colorectal neoplasia: biological and technical basis for high detection rates. Pathology 2012, 44:80-88.
2. Ahlquist D.A., Zou H., Domanico M., et al. Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. Gastroenterology 2012, 142:248-256.
3. Lidgard G.P., Domanico M., Bruinsma J., et al. An optimized multi-marker stool test for colorectal cancer screening: initial clinical appraisal. Gastroenterology 2012, 142(Suppl 1). S-770.
4. Ahlquist D.A., Taylor W.R., Mahoney D.W., et al. The stool DNA test is more accurate than the plasma septin 9 test in detecting colorectal neoplasia. Clin Gastroenterol Hepatol 2012, 10:272-277.
5. Morikawa T., Kato J., Yamaji Y., et al. Acomparison of immunochemical fecal occult blood test and total colonoscopy in the asymptomatic population. Gastroenterology 2012, 129:422-428.
6. Ahlquist D.A., Sargent D.J., Loprinzi C.L., et al. Stool DNA and occult blood testing for screen detection of colorectal neoplasia. Ann Intern Med 2008, 149:441-450.
7. Schoen R.E., Pinsky P.F., Weissfeld J., et al. Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. NEngl J Med 2012, 366:2345-2537.
8. Atkin W.S., Edwards R., Kralj-Hans I., et al. Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomized controlled trial. Lancet 2010, 375:1624-1633.
9. Baxter N.N., Goldwasser M.A., Paszat L.F., et al. Association of colonoscopy and death from colorectal cancer: a population based case-control study. Ann Intern Med 2009, 150:1-8.
10. Brenner H., Chang-Claude J., Seiler C.M., et al. Protection from colorectal cancer after colonoscopy. Ann Intern Med 2011, 154:22-30.
11. Brenner H., Hoffmeister M., Volker A., et al. Protection from right- and left-sided colorectal neoplasms after colonoscopy: population-based study. JNatl Cancer Inst 2010, 102:89-95.
12. Zou H., Allawi H., Cao X., et al. Quantification of methylated markers with a multiplex methylation-specific technology. Clin Chem 2012, 58:375-383.
13. Lieberman D.A., Rex D.K., Winawer S.J., et al. Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology 2012, 143:844-857.
14. Pickhardt P.J., Hain K.S., Kim D.H. Low rates of cancer or high-grade dysplasia in colorectal polyp collected from computed tomography colonography screening. Clin Gastroenterol Hepatol 2010, 8:610-615.
15. Kahi C.J., Hewett D.G., Norton D.L., et al. Prevalence and variable detection of proximal colon serrated polyps during screening colonoscopy. Clin Gastroenterol Hepatol 2011, 9:42-46.
16. Kaminski M.F., Regula J., Kraszewska E., et al. Quality indicators for colonoscopy and the risk of interval cancer. NEngl J Med 2010, 362:1795-1803.