Towards a rational combination therapy of cystic fibrosis: How cystamine restores the stability of mutant CFTR

Autophagy

Volumn 9, Issue 9, 2013, Pages 1431-1434

  Villella, Valeria R ^a   Esposito, Speranza ^a   Maiuri, Maria Chiara ^b,c   Raia, Valeria ^b   Kroemer, Guido ^c,d,e,f,g   Maiuri, Luigi ^a,h  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c INSERM   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e INSTITUT GUSTAVE ROUSSY   (France)

^f CENTRE DE RECHERCHE DES CORDELIERS   (France)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^h UNIVERSITY OF FOGGIA   (Italy)

Author keywords

Autophagy; CFTR; Conformational diseases; Cystic fibrosis; Proteostasis

Indexed keywords

3 METHYLADENINE; CYSTAMINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; MERCAPTAMINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; PROTEIN P62; REACTIVE OXYGEN METABOLITE;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BINDING AFFINITY; BIOTINYLATION; BRONCHUS MUCOSA; CELL MEMBRANE; CYSTIC FIBROSIS; EPITHELIUM CELL; HUMAN; LUNG FIBROSIS; NONHUMAN; PATHOGENESIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; WILD TYPE;

AUTOPHAGY; CFTR; CONFORMATIONAL DISEASES; CYSTIC FIBROSIS; PROTEOSTASIS;

ANIMALS; CYSTAMINE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DRUG THERAPY, COMBINATION; HUMANS; MICE; MODELS, BIOLOGICAL; MUTANT PROTEINS; MUTATION;

EID: 84884308081     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.25517     Document Type: Article

References (0)