Validation of UV spectrophotometric and HPLC methods for quantitative determination of iloperidone in pharmaceutical dosage form

International Journal of PharmTech Research

Volumn 4, Issue 2, 2012, Pages 576-581

  Manjula Devi, A S ^a   Ravi, T K ^a  

^a India)   (India)

Author keywords

ICH guidelines; Iloperidone; Internal standard; RP HPLC; UV spectrophotometric

Indexed keywords

ILOPERIDONE; ILOSURE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG DETERMINATION; DRUG STABILITY; EQUIPMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; ULTRAVIOLET SPECTROPHOTOMETRY; VALIDATION STUDY;

EID: 84884306413     PISSN: 09744304     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Thomson Reuters, Micromedex (R) Healthcare series, 2011, 148.
2. Mutlib AE and Strupczewski JT., Picogram determination of iloperidone in human plasma by solid-phase extraction and by high-performance liquid chromatography-selected-ion monitoring electrospray mass spectrometry, Journal of chromatography B., 1995, 669, 237-246.
3. Mutlib AE and Klein JT., Application of liquid chromatography/mass spectrometry in accelerating the identification of human liver cytochrome P450 isoforms Involved in the metabolism of iloperidone, JPET., 1998, 286, 1285-1293.
4. Mandpe LP and Varsha, BP., Stress degradation studies on iloperidone and development of a stability indicating HPLC method for bulk drug and pharmaceutical dosage form, Der Chemica Sinica.,2011, 2, 230-239.
5. Snyder LR, Kirkland JJ and Glajch JL, Practical HPLC Method Development, 2nd ed., John Wiley and Sons, New York, 1997, 165.
6. Willard HL, Merritt, LL Dean JA and Settle FA. Instrumental Methods of Analysis, 7th ed, Wadsworth Publishing Company, California, 1988, 196.
7. International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH Harmonised Tripartite Guideline - Validation of Analytical Procedures:Text and Methodology Q2(R1), Current Step 4 version, London 2005.