One night on-call: Sleep deprivation affects cardiac autonomic control and inflammation in physicians

European Journal of Internal Medicine

Volumn 24, Issue 7, 2013, Pages 664-670

  Tobaldini, Eleonora ^a   Cogliati, Chiara ^a   Fiorelli, Elisa M ^a   Nunziata, Vanessa ^a   Wu, Maddalena A ^a   Prado, Marta ^a   Bevilacqua, Maurizio ^a   Trabattoni, Daria ^b   Porta, Alberto ^c   Montano, Nicola ^a,d  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

Author keywords

Acute sleep deprivation; Autonomic nervous system; Heart rate variability; Inflammation; Resident physicians

Indexed keywords

ADRENALIN; ALDOSTERONE; CORTICOTROPIN; GAMMA INTERFERON; HYDROCORTISONE; NORADRENALIN; RENIN;

ADULT; ARTICLE; BLOOD PRESSURE VARIABILITY; CLINICAL ARTICLE; DYNAMICS; FEMALE; HEART RATE VARIABILITY; HEMODYNAMICS; HORMONE DETERMINATION; HUMAN; IMMUNE RESPONSE; INFLAMMATION; MALE; NIGHT WORK; PHYSICIAN; PRESSORECEPTOR REFLEX; RESIDENT; SLEEP DEPRIVATION;

ACUTE SLEEP DEPRIVATION; ANS; ASD; AUTONOMIC NERVOUS SYSTEM; BAROREFLEX SENSITIVITY; BLOOD PRESSURE; BLOOD PRESSURE VARIABILITY; BMI; BODY MASS INDEX; BP; BPV; BRS; HEAD-UP TILT; HEART RATE; HEART RATE VARIABILITY; HF; HIGH FREQUENCY; HR; HRV; HUT; INFLAMMATION; LF; LOW FREQUENCY; PBMC; PERIPHERAL BLOOD MONONUCLEAR CELLS; RESIDENT PHYSICIANS; VERY LOW FREQUENCY; VLF;

ADULT; AUTONOMIC NERVOUS SYSTEM; BAROREFLEX; BIOLOGICAL MARKERS; BLOOD PRESSURE; FEMALE; HEART RATE; HORMONES; HUMANS; INFLAMMATION; MALE; MEDICAL STAFF, HOSPITAL; NIGHT CARE; PERSONNEL STAFFING AND SCHEDULING; SLEEP DEPRIVATION; WORK SCHEDULE TOLERANCE;

EID: 84884291916     PISSN: 09536205     EISSN: 18790828     Source Type: Journal    
DOI: 10.1016/j.ejim.2013.03.011     Document Type: Article

References (47)

1. D.L. Wingard, L.F. Berkman, and R.J. Brand A multivariate analysis of health-related practices: a nine-year mortality follow-up of the Alameda County Study Am J Epidemiol 116 1982 765 775
2. D.F. Kripke, L. Garfinkel, D.L. Wingard, M.R. Klauber, and M.R. Marler Mortality associated with sleep duration and insomnia Arch Gen Psychiatry 59 2002 131 136
3. L. Gallicchio, and B. Kalesan Sleep duration and mortality: a systematic review and meta-analysis J Sleep Res 18 2009 148 158
4. F.P. Cappuccio, L. D'Elia, P. Strazzullo, and M.A. Miller Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies Sleep 33 2010 585 592
5. P. Meerlo, A. Sgoifo, and D. Suchecki Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity Sleep Med Rev 12 2008 197 210
6. B. Takase, T. Akima, K. Satomura, F. Ohsuzu, T. Mastui, and M. Ishihara Effects of chronic sleep deprivation on autonomic activity by examining heart rate variability, plasma catecholamine, and intracellular magnesium levels Biomed Pharmacother 58 2004 S35 S39
7. N.K. Muenter, D.E. Watenpaugh, W.L. Wasmund, S.L. Wasmund, S.A. Maxwell, and M.L.J. Smith Effect of sleep restriction on orthostatic cardiovascular control in humans J Appl Physiol 88 2000 966 972
8. K. Spiegel, R. Leproult, and E. Van Cauter Impact of sleep debt on metabolic and endocrine function Lancet 354 1999 1435 1439
9. O.M. Buxton, M. Pavlova, E.W. Reid, W. Wang, D.C. Simonson, and G.K. Adler Sleep restriction for 1 week reduces insulin sensitivity in healthy men Diabetes 59 2010 2126 2133
10. J.M. Mullington, N.S. Simpson, H.K. Meier-Ewert, and M. Haack Sleep loss and inflammation Best Pract Res Clin Endocrinol Metab 24 2010 775 784
11. W.M. van Leeuwen, M. Lehto, P. Karisola, H. Lindholm, R. Luukkonen, and M. Sallinen Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP PLoS One 4 2009 e4589
12. S.R. Patel, X. Zhu, A. Storfer-Isser, R. Mehra, N.S. Jenny, and R. Tracy Sleep duration and biomarkers of inflammation Sleep 32 2009 200 204
13. C. Anderson, and C.R. Platten Sleep deprivation lowers inhibition and enhances impulsivity to negative stimuli Behav Brain Res 217 2011 463 466
14. I. Sari, V. Davutoglu, B. Ozbala, O. Ozer, Y. Baltaci, and S. Yavuz Acute sleep deprivation is associated with increased electrocardiographic P-wave dispersion in healthy young men and women Pacing Clin Electrophysiol 31 2008 438 442
15. J. Vaara, H. Kyröläinen, M. Koivu, M. Tulppo, and T. Finni The effect of 60-h sleep deprivation on cardiovascular regulation and body temperature Eur J Appl Physiol 105 2009 439 444
16. M. Kato, B.G. Phillips, G. Sigurdsson, K. Narkiewicz, C.A. Pesek, and V.K. Somers Effects of sleep deprivation on neural circulatory control Hypertension 35 2000 1173 1175
17. P. Lusardi, A. Zoppi, P. Preti, R.M. Pesce, E. Piazza, and R. Fogari Effects of insufficient sleep on blood pressure in hypertensive patients: a 24-h study Am J Hypertens 12 1999 63 68
18. F. Sauvet, G. Leftheriotis, D. Gomez-Merino, C. Langrume, C. Drogou, and P. Van Beers Effect of acute sleep deprivation on vascular function in healthy subjects J Appl Physiol 108 2010 68 75
19. Y. Ogawa, T. Kanbayashi, Y. Saito, Y. Takahashi, T. Kitajima, and K. Takahashi Total sleep deprivation elevates blood pressure through arterial baroreflex resetting: a study with microneurographic technique Sleep 26 2003 986 989
20. M. Pagani, P. Pizzinelli, A.P. Traon, C. Ferreri, S. Beltrami, and M.P. Bareille Hemodynamic, autonomic and baroreflex changes after one night sleep deprivation in healthy volunteers Auton Neurosci 145 2009 76 80
21. X. Zhong, H.J. Hilton, G.J. Gates, S. Jelic, Y. Stern, and M.N. Bartels Increased sympathetic and decreased parasympathetic cardiovascular modulation in normal humans with acute sleep deprivation J Appl Physiol 98 2005 2024 2032
22. M. Irwin, J. Thompson, C. Miller, J.C. Gillin, and M. Ziegler Effects of sleep and sleep deprivation on catecholamine and interleukin-2 levels in humans: clinical implications J Clin Endocrinol Metab 84 1999 1979 1985
23. P.K. Opstad, O. Oktedalen, A. Aakvaag, F. Fonnum, and P.K. Lund Plasma renin activity and serum aldosterone during prolonged physical strain. The significance of sleep and energy deprivation Eur J Appl Physiol Occup Physiol 54 1985 1 6
24. L. Redwine, R.L. Hauger, J.C. Gillin, and M. Irwin Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans J Clin Endocrinol Metab 85 2000 3597 3603
25. D.J. Frey, M. Fleshner, and K.P. Wright Jr. The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults Brain Behav Immun 21 2007 1050 1057
26. R.J. Costa, A.H. Smith, S.J. Oliver, R. Walters, N. Maassen, and J.L. Bilzon The effects of two nights of sleep deprivation with or without energy restriction on immune indices at rest and in response to cold exposure Eur J Appl Physiol 109 2010 417 428
27. I. Philibert Sleep loss and performance in residents and nonphysicians: a meta-analytic examination Sleep 28 2005 1392 1402
28. A.D. Saxena, and C.F. George Sleep and motor performance in on-call internal medicine residents Sleep 28 2005 1386 1391
29. B. Malmberg, R. Persson, P. Flisberg, and P. ∅rbaek Heart rate variability changes in physicians working on night call Int Arch Occup Environ Health 84 2011 293 301
30. M.H. Chung, T.B. Kuo, N. Hsu, H. Chu, K.R. Chou, and C.C. Yang Sleep and autonomic nervous system changes - enhanced cardiac sympathetic modulations during sleep in permanent night shift nurses Scand J Work Environ Health 35 2009 180 187
31. D.J. Dula, N.L. Dula, C. Hamrick, and G.C. Wood The effect of working serial night shifts on the cognitive functioning of emergency physicians Ann Emerg Med 38 2001 152 155
32. S.L. Adams, D.M. Roxe, J. Weiss, F. Zhang, and J.E. Rosenthal Ambulatory blood pressure and Holter monitoring of emergency physicians before, during, and after a night shift Acad Emerg Med 5 1998 871 877
33. A. Malliani, M. Pagani, F. Lombardi, and S. Cerutti Cardiovascular neural regulation explored in the frequency domain Circulation 84 1991 482 492
34. A. Malliani, and N. Montano Heart rate variability as a clinical tool Ital Heart J 3 2002 439 445
35. N. Montano, A. Porta, C. Cogliati, G. Costantino, E. Tobaldini, and K.R. Casali Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behavior Neurosci Biobehav Rev 33 2009 71 80
36. M. Pagani, V. Somers, R. Furlan, S. Dell'Orto, J. Conway, and G. Baselli Changes in autonomic regulation induced by physical training in mild hypertension Hypertension 12 1988 600 610
37. A. Sgoifo, B. Buwalda, M. Roos, T. Costoli, G. Merati, and P. Meerlo Effects of sleep deprivation on cardiac autonomic and pituitary-adrenocortical stress reactivity in rats Psychoneuroendocrinology 31 2006 197 208
38. C.P. Landrigan, J.M. Rothschild, J.W. Cronin, R. Kaushal, E. Burdick, and J.T. Katz Effect of reducing interns' work hours on serious medical errors in intensive care units N Engl J Med 351 2004 1838 1848
39. S.W. Lockley, J.W. Cronin, E.E. Evans, B.E. Cade, C.J. Lee, and C.P. Landrigan Effect of reducing interns' weekly work hours on sleep and attentional failures N Engl J Med 351 2004 1829 1837
40. S.K. Mak, and P. Spurgeon The effects of acute sleep deprivation on performance of medical residents in a regional hospital: prospective study Hong Kong Med J 10 2004 14 20
41. M. Carev, N. Karanović, J. Bagatin, N.B. Matulić, R. Pecotić, and M. Valić Blood pressure dipping and salivary cortisol as markers of fatigue and sleep deprivation in staff anesthesiologists Coll Antropol 35 2011 133 138
42. N. Montano, T.G. Ruscone, A. Porta, F. Lombardi, M. Pagani, and A. Malliani Power spectrum analysis of heart rate variability to assess the changes in sympathovagal balance during graded orthostatic tilt Circulation 90 1994 1826 1831
43. M. Pagani, G. Malfatto, S. Pierini, R. Casati, A.M. Masu, and M. Poli Spectral analysis of heart rate variability in the assessment of autonomic diabetic neuropathy J Auton Nerv Syst 23 1988 143 153
44. A. Charloux, C. Gronfier, F. Chapotot, J. Ehrhart, F. Piquard, and G. Brandenberger Sleep deprivation blunts the night time increase in aldosterone release in humans J Sleep Res 10 2001 27 33
45. F.S. Ruiz, M.L. Andersen, R.C. Martins, A. Zager, J.D. Lopes, and S. Tufik Immune alterations after selective rapid eye movement or total sleep deprivation in healthy male volunteers Innate Immun 18 2012 44 54
46. N.W. Kin, and V.M. Sanders It takes nerve to tell T and B cells what to do J Leukoc Biol 79 2006 1093 1104
47. K.J. Tracey The inflammatory reflex Nature 420 2002 853 859