Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer

Breast Cancer Research and Treatment

Volumn 141, Issue 1, 2013, Pages 119-123

  Di Lauro, Luigi ^a   Vici, Patrizia ^a   Del Medico, Pietro ^b   Laudadio, Lucio ^c   Tomao, Silverio ^d   Giannarelli, Diana ^a   Pizzuti, Laura ^a   Sergi, Domenico ^a   Barba, Maddalena ^a   Maugeri Saccà, Marcello ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b Reggio Calabria General Hospital   (Italy)

^c Renzetti Hospital   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Endocrine therapy; Gonadotropin releasing hormone analog; Letrozole; Male breast cancer; Metastatic disease

Indexed keywords

ANASTROZOLE; CYCLOPHOSPHAMIDE; DOCETAXEL; EPIRUBICIN; EXEMESTANE; FLUOROURACIL; GONADORELIN DERIVATIVE; GOSERELIN; LETROZOLE; LEUPRORELIN; METHOTREXATE; TAMOXIFEN; TRIPTORELIN;

ADULT; AGED; ARTICLE; BONE METASTASIS; BREAST METASTASIS; CLINICAL ARTICLE; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; HUMAN; ITALY; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; MALE; MALE BREAST CANCER; MASTECTOMY; METASTATIC MALE BREAST CANCER; MONOTHERAPY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RETROSPECTIVE STUDY; SKIN METASTASIS; SURVIVAL RATE; UNSPECIFIED SIDE EFFECT;

AGED; ANTINEOPLASTIC AGENTS, HORMONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AROMATASE INHIBITORS; BREAST NEOPLASMS, MALE; CARCINOMA, DUCTAL, BREAST; CARCINOMA, PAPILLARY; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; CYCLOPHOSPHAMIDE; DISEASE-FREE SURVIVAL; EPIRUBICIN; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; FLUOROURACIL; GONADOTROPIN-RELEASING HORMONE; GOSERELIN; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MASTECTOMY, MODIFIED RADICAL; METHOTREXATE; MIDDLE AGED; NEOPLASMS, HORMONE-DEPENDENT; NITRILES; PROGESTERONE; RADIOTHERAPY, ADJUVANT; TAMOXIFEN; TAXOIDS; TRIAZOLES;

EID: 84884283776     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2675-y     Document Type: Article

References (25)

1. Ruddy KJ, Winer EP (2013) Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship. Ann Oncol 24:1434-1443
2. Sousa B, Moser E, Cardoso F (2013) An update on male breast cancer and future directions for research and treatment. Eur J Pharmacol. doi: 10.1016/j.ejphar.2013.03.037
3. Johansson I, Nilsson C, Berglund P et al (2012) Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies nacetyltransferase-1 (NAT1) as a novel prognostic biomarker. Breast Cancer Res 14:R31
4. Anderson WF, Jatoi I, Tse J, Rosenberg PS (2010) Male breast cancer: a population-based comparison with female breast cancer. J Clin Oncol 28:232-239
5. Cardoso F, Bischoff J, Brain E et al (2013) A review of the treatment of endocrine responsive metastatic breast cancer in postmenopausal women. Cancer Treat Rev 39:457-465
6. Eggemann H, Ignatov A, Smith BJ et al (2013) Adjuvant therapy with tamoxifen compared to aromatase inhibitors for 257 male breast cancer patients. Breast Cancer Res Treat 137:465-470
7. Vermeulen A, Kaufman JM, Goemaere S, van Pottelberg I (2002) Estradiol in elderly men. Aging Male 5:98-102
8. Hemsell DL, Grodin JM, Brenner PF, Siiteri PK, MacDonald PC (1974) Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab 38:476-479
9. Mauras N, O'Brien KO, Klein KO, Hayes V (2000) Estrogen suppression in males: metabolic effects. J Clin Endocrinol Metab 85:2370-2377
10. T'Sjoen GG, Giagulli VA, Delva H, Crabbe P, De Bacquer D, Kaufman JM (2005) Comparative assessment in young and elderly men of the gonadotropin response to aromatase inhibition. J Clin Endocrinol Metab 90:5717-5722
11. Callari M, Cappelletti V, De Cecco L et al (2011) Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer. Breast Cancer Res Treat 127:601-610
12. White J, Kearins O, Dodwell D, Horgan K, Hanby AM, Speirs V (2011) Male breast carcinoma: increased awareness needed. Breast Cancer Res 13:219
13. Lopez M, Di Lauro L, Lazzaro B, Papaldo P (1985) Hormonal treatment of disseminated male breast cancer. Oncology 42:345-349
14. Lopez M, Natali M, Di Lauro L, Vici P, Pignatti F, Carpano S (1993) Combined treatment with buserelin and cyproterone acetate in metastatic male breast cancer. Cancer 72:502-505
15. Doberauer C, Niederle N, Schmidt CG (1988) Advanced male breast cancer treatment with the LH-RH analogue buserelin alone or in combination with the antiandrogen flutamide. Cancer 62:474-478
16. Patterson JS, Battersby LA, Bach BK (1980) Use of tamoxifen in advanced male breast cancer. Cancer Treat Rep 64:801-804
17. Dakin Haché K, Gray S, Barnes PJ, Dewar R, Younis T, Rayson D (2007) Clinical and pathological correlations in male breast cancer: intratumoral aromatase expression via tissue microarray. Breast Cancer Res Treat 105:169-175
18. Doyen J, Italiano A, Largillier R, Ferrero JM, Fontana X, Thyss A (2010) Aromatase inhibition in male breast cancer patients: biological and clinical implications. Ann Oncol 21:1243-1245
19. Turner KJ, Morley M, Atanassova N, Swanston ID, Sharpe RM (2000) Effect of chronic administration of an aromatase inhibitor to adult male rats on pituitary and testicular function and fertility. J Endocrinol 164:225-238
20. Giordano SH, Hortobagyi GN (2006) Leuprolide acetate plus aromatase inhibition for male breast cancer. J Clin Oncol 24:e42-e43
21. Zagouri F, Sergentanis TN, Koutoulidis V et al (2013) Aromatase inhibitors with or without gonadotropin-releasing hormone analogue in metastatic male breast cancer: a case series. Br J Cancer 108:2259-2263
22. Giordano SH, Valero V, Buzdar AU, Hortobagyi GN (2002) Efficacy of anastrozole in male breast cancer. Am J Clin Oncol 25:235-237
23. Italiano A, Largillier R, Marcy PY et al (2004) Complete remission obtained with letrozole in a man with metastatic breast cancer. Rev Med Interne 25:323-324
24. Zabolotny BP, Zalai CV, Meterissian SH (2005) Successful use of letrozole in male breast cancer: a case report and review of hormonal therapy for male breast cancer. J Surg Oncol 90:26-30
25. Arriola E, Hui E, Dowsett M, Smith IE (2007) Aromatase inhibitors and male breast cancer. Clin Transl Oncol 9:192-194