DNA microarray for genotyping antibiotic resistance determinants in acinetobacter baumannii clinical isolates

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 10, 2013, Pages 4761-4768

  Dally, Simon ^a   Lemuth, Karin ^b,d   Kaase, Martin ^c   Rupp, Steffen ^b   Knabbe, Cornelius ^a   Weile, Jan ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b FRAUNHOFER INSTITUTE FOR INTERFACIAL ENGINEERING AND BIOTECHNOLOGY IGB   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d ROBERT BOSCH GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; CARBAPENEMASE; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TAZOBACTAM; TIGECYCLINE; TOBRAMYCIN;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM CULTURE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA MICROARRAY; GENE OVEREXPRESSION; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; MINIMUM INHIBITORY CONCENTRATION; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; POINT MUTATION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENOTYPE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 84884234854     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00863-13     Document Type: Article

References (37)

1. Armstrong GL, Conn LA, Pinner RW. 1999. Trends in infectious disease mortality in the United States during the 20th century. JAMA 281:61-66.
2. van Hoek AH, Mevius D, Guerra B, Mullany P, Roberts AP, Aarts HJ. 2011. Acquired antibiotic resistance genes: an overview. Front. Microbiol. 2:203.
3. Weile J, Schmid RD, Bachmann TT, Susa M, Knabbe C. 2007. DNA microarray for genotyping multidrug-resistant Pseudomonas aeruginosa clinical isolates. Diagn. Microbiol. Infect. Dis. 59:325-338.
4. Card R, Zhang J, Das P, Cook C, Woodford N, Anjum MF. 2013. Evaluation of an expanded microarray for detecting antibiotic resistance genes in a broad range of gram-negative bacterial pathogens. Antimicrob. Agents Chemother. 57:458-465.
5. Batchelor M, Hopkins KL, Liebana E, Slickers P, Ehricht R, Mafura M, Aarestrup F, Mevius D, Clifton-Hadley FA, Woodward MJ, Davies RH, Threlfall EJ, Anjum MF. 2008. Development of a miniaturised microarray-based assay for the rapid identification of antimicrobial resistance genes in Gram-negative bacteria. Int. J. Antimicrob. Agents 31:440-451.
6. Leinberger DM, Grimm V, Rubtsova M, Weile J, Schroppel K, Wichelhaus TA, Knabbe C, Schmid RD, Bachmann TT. 2010. Integrated detection of extended-spectrum-beta-lactam resistance by DNA microarray-based genotyping of TEM, SHV, andCTX-Mgenes. J. Clin. Microbiol. 48:460-471.
7. Strommenger B, Schmidt C, Werner G, Roessle-Lorch B, Bachmann TT, Witte W. 2007. DNA microarray for the detection of therapeutically relevant antibiotic resistance determinants in clinical isolates of Staphylococcus aureus. Mol. Cell. Probes 21:161-170.
8. Perreten V, Vorlet-Fawer L, Slickers P, Ehricht R, Kuhnert P, Frey J. 2005. Microarray-based detection of 90 antibiotic resistance genes of gram-positive bacteria. J. Clin. Microbiol. 43:2291-2302.
9. Dijkshoorn L, van Aken E, Shunburne L, van der Reijden TJ, Bernards AT, Nemec A, Towner KJ. 2005. Prevalence of Acinetobacter baumannii and other Acinetobacter spp. in faecal samples from non-hospitalised individuals. Clin. Microbiol. Infect. 11:329-332.
10. Doi Y, Husain S, Potoski BA, McCurry KR, Paterson DL. 2009. Extensively drug-resistant Acinetobacter baumannii. Emerg. Infect. Dis. 15: 980-982.
11. Peleg AY, Seifert H, Paterson DL. 2008. Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol. Rev. 21:538-582.
12. Valles J, Rello J, Ochagavia A, Garnacho J, Alcala MA. 2003. Community-acquired bloodstream infection in critically ill adult patients: impact of shock and inappropriate antibiotic therapy on survival. Chest 123: 1615-1624.
13. Luna CM. 2003. Blood cultures in community-acquired pneumonia: are we ready to quit? Chest 123:977-978.
14. Liu P-F, Wu W-L. 1997. Use of different PCR-based DNA fingerprinting techniques and pulsed-field gel electrophoresis to investigate the epidemiology of Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Diagn. Microbiol. Infect. Dis. 29:19-28.
15. Turton JF, Woodford N, Glover J, Yarde S, Kaufmann ME, Pitt TL. 2006. Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species. J. Clin. Microbiol. 44:2974-2976.
16. Grimm V, Ezaki S, Susa M, Knabbe C, Schmid RD, Bachmann TT. 2004. Use of DNA microarrays for rapid genotyping of TEM betalactamases that confer resistance. J. Clin. Microbiol. 42:3766-3774.
17. Fournier PE, Vallenet D, Barbe V, Audic S, Ogata H, Poirel L, Richet H, Robert C, Mangenot S, Abergel C, Nordmann P, Weissenbach J, Raoult D, Claverie JM. 2006. Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet. 2:e7. doi:10.1371/journal .pgen.0020007.
18. Ambler RP. 1980. The structure of beta-lactamases. Philos. Trans. R. Soc. Lond. B Biol. Sci. 289:321-331.
19. Wachino J, Doi Y, Yamane K, Shibata N, Yagi T, Kubota T, Arakawa Y. 2004. Molecular characterization of a cephamycin-hydrolyzing and inhibitor-resistant class A beta-lactamase, GES-4, possessing a single G170S substitution in the omega-loop. Antimicrob. Agents Chemother. 48: 2905-2910.
20. Bonnin RA, Nordmann P, Potron A, Lecuyer H, Zahar JR, Poirel L. 2011. Carbapenem-hydrolyzing GES-type extended-spectrum betalactamase in Acinetobacter baumannii. Antimicrob. Agents Chemother. 55:349-354.
21. Fernandez-Cuenca F, Martinez-Martinez L, Conejo MC, Ayala JA, Perea EJ, Pascual A. 2003. Relationship between beta-lactamase production, outer membrane protein and penicillin-binding protein profiles on the activity of carbapenems against clinical isolates of Acinetobacter baumannii. J. Antimicrob. Chemother. 51:565-574.
22. Ribera A, Fernandez-Cuenca F, Beceiro A, Bou G, Martinez-Martinez L, Pascual A, Cisneros JM, Rodriguez-Bano J, Pachon J, Vila J. 2004. Antimicrobial susceptibility and mechanisms of resistance to quinolones and beta-lactams in Acinetobacter genospecies 3. Antimicrob. Agents Chemother. 48:1430-1432.
23. Akers KS, Chaney C, Barsoumian A, Beckius M, Zera W, Yu X, Guymon C, Keen EF, III, Robinson BJ, Mende K, Murray CK. 2010. Aminoglycoside resistance and susceptibility testing errors in Acinetobacter baumannii-calcoaceticus complex. J. Clin. Microbiol. 48:1132-1138.
24. Jung S, Yu JK, Shin SH, Park KG, Jekarl DW, Han K, Park YJ. 2010. False susceptibility to amikacin by VITEK 2 in Acinetobacter baumannii harboring armA. Ann. Clin. Lab. Sci. 40:167-171.
25. Vila J, Ruiz J, Navia M, Becerril B, Garcia I, Perea S, Lopez-Hernandez I, Alamo I, Ballester F, Planes AM, Martinez-Beltran J, de Anta TJ. 1999. Spread of amikacin resistance in Acinetobacter baumannii strains isolated in Spain due to an epidemic strain. J. Clin. Microbiol. 37:758-761.
26. Salipante SJ, Hall BG. 2003. Determining the limits of the evolutionary potential of an antibiotic resistance gene. Mol. Biol. Evol. 20:653-659.
27. Hornsey M, Ellington MJ, Doumith M, Thomas CP, Gordon NC, Wareham DW, Quinn J, Lolans K, Livermore DM, Woodford N. 2010. AdeABC-mediated efflux and tigecycline MICs for epidemic clones of Acinetobacter baumannii. J. Antimicrob. Chemother. 65:1589-1593.
28. Marchand I, Damier-Piolle L, Courvalin P, Lambert T. 2004. Expression of the RND-type efflux pump AdeABC in Acinetobacter baumannii is regulated by the AdeRS two-component system. Antimicrob. Agents Chemother. 48:3298-3304.
29. Sun JR, Perng CL, Chan MC, Morita Y, Lin JC, Su CM, Wang WY, Chang TY, Chiueh TS. 2012. A truncated AdeS kinase protein generated by ISAba1 insertion correlates with tigecycline resistance in Acinetobacter baumannii. PLoS One 7:e49534. doi:10.1371/journal.pone.0049534.
30. Cuzon G, Naas T, Bogaerts P, Glupczynski Y, Nordmann P. 2012. Evaluation of a DNA microarray for the rapid detection of extendedspectrum-lactamases (TEM, SHV and CTX-M), plasmid-mediated cephalosporinases (CMY-2-like, DHA, FOX, ACC-1, ACT/MIR and CMY-1-like/MOX) and carbapenemases (KPC, OXA-48, VIM, IMP and NDM). J. Antimicrob. Chemother. 67:1865-1869.
31. Naas T, Cuzon G, Truong H, Bernabeu S, Nordmann P. 2010. Evaluation of a DNA microarray, the Check-Points ESBL/KPC array, for rapid detection of TEM, SHV, and CTX-M extended-spectrum-lactamases and KPC carbapenemases. Antimicrob. Agents Chemother. 54:3086-3092.
32. Vahaboglu H, Budak F, Kasap M, Gacar G, Torol S, Karadenizli A, Kolayli F, Eroglu C. 2006. High prevalence of OXA-51-type class D beta-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: co-existence with OXA-58 in multiple centres. J. Antimicrob. Chemother. 58:537-542.
33. Kaase M, Nordmann P, Wichelhaus TA, Gatermann SG, Bonnin RA, Poirel L. 2011. NDM-2 carbapenemase in Acinetobacter baumannii from Egypt. J. Antimicrob. Chemother. 66:1260-1262.
34. Gottig S, Pfeifer Y, Wichelhaus TA, Zacharowski K, Bingold T, Averhoff B, Brandt C, Kempf VA. 2010. Global spread of New Delhi metallobeta-lactamase 1. Lancet Infect. Dis. 10:828-829.
35. Roh SW, Abell GC, Kim K-H, Nam Y-D, Bae J-W. 2010. Comparing microarrays and next-generation sequencing technologies for microbial ecology research. Trends Biotechnol. 28:291-299.
36. Moffatt JH, Harper M, Adler B, Nation RL, Li J, Boyce JD. 2011. Insertion sequence ISAba11 is involved in colistin resistance and loss of lipopolysaccharide in Acinetobacter baumannii. Antimicrob. Agents Chemother. 55:3022-3024.
37. Moffatt JH, Harper M, Harrison P, Hale JD, Vinogradov E, Seemann T, Henry R, Crane B, St Michael F, Cox AD, Adler B, Nation RL, Li J, Boyce JD. 2010. Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production. Antimicrob. Agents Chemother. 54:4971-4977.