1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 5, 2013, Pages 974-980

  Bilginer, Sinan ^a   Gul, Halise Inci ^a   Mete, Ebru ^a   Das, Umashankar ^b   Sakagami, Hiroshi ^c   Umemura, Naoki ^c   Dimmock, Jonathan Richard ^b  

^a ATATÜRK UNIVERSITY   (Turkey)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Azachalcones; Cytotoxicity; Mannich bases; Molecular modelling; PARP1

Indexed keywords

1 (3 AMINOMETHYL 4 HYDROXYPHENYL) 3 PYRIDINYL 2 PROPEN 1 ONE DERIVATIVE; 4 HYDROXYACETOPHENONE; ACETONITRILE; ANTINEOPLASTIC AGENT; CYTOTOXIN; MANNICH BASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; HUMAN; LEUKEMIA CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; SQUAMOUS CELL CARCINOMA;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; MOLECULAR STRUCTURE; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84884233598     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2012.700927     Document Type: Article

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