Translational approaches to the biology of Autism: False dawn or a new era

Molecular Psychiatry

Volumn 18, Issue 4, 2013, Pages 435-442

  Ecker, C ^a   Spooren, W ^b   Murphy, D G M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Autism spectrum disorder; biomarkers; drug development; genetics; neuroimaging

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; BIOLOGICAL MARKER; CONTACTIN; CONTACTIN ASSOCIATED PROTEIN 2; DNA FRAGMENT; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; NEUREXIN; NEUROLIGIN; PROTEIN; SEROTONIN TRANSPORTER; SHANK3 PROTEIN; UNCLASSIFIED DRUG;

AUDITORY STIMULATION; AUTISM; BRAIN SIZE; CELL ADHESION; CHROMOSOME 2; CINGULATE GYRUS; CLINICAL PRACTICE; COGNITION; COPY NUMBER VARIATION; DIAGONAL BAND OF BROCA; DRUG DEVELOPMENT; ENZYME INHIBITION; FRONTAL CORTEX; FRONTAL LOBE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GABAERGIC TRANSMISSION; GENE LOCATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GRAY MATTER; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LEARNING; MEMORY; MULTICENTER STUDY (TOPIC); NERVE CELL DIFFERENTIATION; NEUROANATOMY; NEUROIMAGING; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBSESSIVE COMPULSIVE DISORDER; PARIETAL LOBE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SOCIAL INTERACTION; SOCIAL PHOBIA; SOMATOSENSORY CORTEX; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS; TEMPORAL LOBE; VISUAL CORTEX; VISUAL STIMULATION; WERNICKE AREA; WHITE MATTER;

BIOLOGICAL MARKERS; BRAIN; CEREBRAL CORTEX; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; DRUG DISCOVERY; HUMANS; MODELS, NEUROLOGICAL; NEURAL PATHWAYS; SYNAPTIC TRANSMISSION; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84884211527     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2012.102     Document Type: Review

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