The aqueous extract of Lycopus lucidus Turcz ameliorates streptozotocin-induced diabetic renal damage via inhibiting TGF-β1 signaling pathway

Phytomedicine

Volumn 20, Issue 13, 2013, Pages 1160-1167

  Yao, Yuanzhang ^a   Yang, Jie ^a   Wang, Dawei ^a   Zhou, Fei ^a   Cai, Xueting ^a   Lu, Wuguang ^a   Hu, Chunping ^a   Gu, Zhenghua ^a   Qian, Shihui ^a   Guan, Xiaoxiang ^b   Cao, Peng ^a  

^a Jiangsu Province Institute of Traditional Chinese Medicine   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Lycopus lucidus; renal disease; Smad; TGF

Indexed keywords

LYCOPUS LUCIDUS EXTRACT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PLANT EXTRACT; SMAD2 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CHINESE HERB; COMPETITIVE INHIBITION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; KIDNEY FIBROSIS; KIDNEY INJURY; LYCOPUS LUCIDUS; MALE; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RENAL PROTECTION; SIGNAL TRANSDUCTION; URINE VOLUME;

LYCOPUS; LYCOPUS ASPER; RATTUS;

LYCOPUS LUCIDUS; RENAL DISEASE; SMAD; TGF-Β;

ANIMALS; CAFFEIC ACIDS; CELL LINE; CINNAMATES; DEPSIDES; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; FIBROSIS; GENE EXPRESSION REGULATION; GLUCOSIDES; HUMANS; LUTEOLIN; LYCOPUS; MALE; MICE; PHOSPHORYLATION; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84884210628     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.06.004     Document Type: Article

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