Antigen identification using SEREX

Methods in Molecular Biology

Volumn 1061, Issue , 2013, Pages 59-77

  Sahin, Ugur ^a   Türeci, Özlem ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Autoantibodies; Autoantigens; Biomarker; Expression cloning; Immunoproteomics; SEREX; Serology

Indexed keywords

AUTOANTIGEN; COMPLEMENTARY DNA; DOUBLE STRANDED DNA;

ANTIGEN DETECTION; ARTICLE; BACTERIOPHAGE LAMBDA; HUMAN; NONHUMAN; PHAGEMID; PRIORITY JOURNAL; SCREENING TEST; SEROLOGICAL ANALYSIS OF RECOMBINANT CDNA EXPRESSION LIBRARY; SEROLOGY; VALIDATION PROCESS;

ANTIGENS; AUTOIMMUNE DISEASES; DNA, COMPLEMENTARY; GENE LIBRARY; HUMANS; NEOPLASMS;

EID: 84884194754     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-589-7_3     Document Type: Article

References (13)

1. Sahin U, Türeci O, Schmitt H, Cochlovius B, Johannes T, Schmits R, Stenner F, Luo G, Schobert I, Pfreundschuh M (1995) Human neoplasms elicit multiple specific immune responses in the autologous host. Proc Natl Acad Sci U S A 92:11810-11813
2. Rauch J, Gires O (2008) SEREX, Proteomex, AMIDA, and beyond: serological screening technologies for target identification. Proteomics Clin Appl 2:355-371
3. Krebs P, Kurrer M, Sahin U, Türeci O, Ludewig B (2003) Autoimmunity seen through the SEREX-scope. Autoimmun Rev 2(6):339-345
4. Old LJ, Chen YT (1998) New paths in human cancer serology. J Exp Med 187:1163-1167
5. Chomczynski P, Sacchi N (1987) Anal Biochem 162:156-159
6. Diatchenko L, Lukyanov S, Lau YF, Siebert PD (1999) Suppression subtractive hybridisation: a versatile method for identifying differentially expressed genes. Methods Enzymol 303:349-380
7. Türeci Ö, Schmitt H, Fadle N, Pfreundschuh M, Sahin U (1997) Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. J Biol Chem 272:6416-6422
8. Stockert E, Jäger E, Chen YT, Scanlan MJ, Gout I, Karbach J, Arand M, Knuth A, Old LJ (1998) A survey of the humoral immune response of cancer patients to a panel of human tumor antigens. J Exp Med 187:1349-1354
9. Lagarkova MA, Koroleva EP, Kuprash DV, Boitchenko VE, Kashkarova UA, Nedospasov SA, Shebzukhov YV (2003) Evaluation of humoral response to tumor antigens using recombinant expression-based serological mini-arrays (SMARTA). Immunol Lett 85:71-74
10. Scanlan MJ, Welt S, Gordon CM, Chen YT, Gure AO, Stockert E, Jungbluth AA, Ritter G, Jager D, Jager E, Knuth A, Old LJ (2002) Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets. Cancer Res 62:4041-4047
11. Türeci Ö, Luxemburger U, Heinen H, Mack U, Ukena D, Sybrecht GW, Huber C, Sahin U (2006) CrELISA: a fast and robust enzyme linked immuno sorbent assay bypassing the need for purification of recombinant protein. Cancer Lett 236:64-71
12. Gnjatic S, Wheeler C, Ebner M, Ritter E, Murray A, Altorki NK, Ferrara CA, Hepburne-Scott H, Joyce S, Koopman J, McAndrew MB, Workman N, Ritter G, Fallon R, Old LJ (2009) Seromic analysis of antibody responses in non-small cell lung cancer patients and healthy donors using conformational protein arrays. J Immunol Methods 341:50-58
13. Krause P, Türeci Ö, Micke P, Buhl R, Huber C, Sahin U (2003) SeroGRID: an improved method for the rapid selection of antigens with disease related immunogenicity. J Immunol Methods 283:261-267