메뉴 건너뛰기




Volumn 8, Issue 9, 2013, Pages

Lmx1a Encodes a Rostral Set of Mesodiencephalic Dopaminergic Neurons Marked by the Wnt/B-Catenin Signaling Activator R-spondin 2

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; NUCLEAR RECEPTOR RELATED FACTOR 1; TRANSCRIPTION FACTOR PBX1; TRANSCRIPTION FACTOR PITX2; TRANSCRIPTION FACTOR POU4F1; WNT PROTEIN;

EID: 84884187461     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074049     Document Type: Article
Times cited : (35)

References (52)
  • 1
    • 84859218841 scopus 로고    scopus 로고
    • Pluripotent stem cells for the study of CNS development
    • doi:10.3389/fnmol.2011.00030
    • Petros TJ, Tyson JA, Anderson SA, (2011) Pluripotent stem cells for the study of CNS development. Front Mol Neurosci 4: 30 doi:10.3389/fnmol.2011.00030.
    • (2011) Front Mol Neurosci , vol.4 , pp. 30
    • Petros, T.J.1    Tyson, J.A.2    Anderson, S.A.3
  • 2
    • 33747670219 scopus 로고    scopus 로고
    • Genetic networks controlling the development of midbrain dopaminergic neurons
    • doi:10.1113/jphysiol.2006.113464
    • Prakash N, Wurst W, (2006) Genetic networks controlling the development of midbrain dopaminergic neurons. J Physiol (Lond) 575: 403-410 doi:10.1113/jphysiol.2006.113464.
    • (2006) J Physiol (Lond) , vol.575 , pp. 403-410
    • Prakash, N.1    Wurst, W.2
  • 3
    • 32644456479 scopus 로고    scopus 로고
    • Developmental origin and fate of meso-diencephalic dopamine neurons
    • doi:10.1016/j.pneurobio.2005.12.003
    • Smits SM, Burbach JPH, Smidt MP, (2006) Developmental origin and fate of meso-diencephalic dopamine neurons. Prog Neurobiol 78: 1-16 doi:10.1016/j.pneurobio.2005.12.003.
    • (2006) Prog Neurobiol , vol.78 , pp. 1-16
    • Smits, S.M.1    Burbach, J.P.H.2    Smidt, M.P.3
  • 4
    • 33244474408 scopus 로고    scopus 로고
    • Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2
    • doi:10.1242/dev.02224
    • Andersson E, Jensen JB, Parmar M, Guillemot F, Björklund A, (2006) Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development 133: 507-516 doi:10.1242/dev.02224.
    • (2006) Development , vol.133 , pp. 507-516
    • Andersson, E.1    Jensen, J.B.2    Parmar, M.3    Guillemot, F.4    Björklund, A.5
  • 5
    • 31044445499 scopus 로고    scopus 로고
    • Identification of intrinsic determinants of midbrain dopamine neurons
    • doi:10.1016/j.cell.2005.10.037
    • Andersson E, Tryggvason U, Deng Q, Friling S, Alekseenko Z, et al. (2006) Identification of intrinsic determinants of midbrain dopamine neurons. Cell 124: 393-405 doi:10.1016/j.cell.2005.10.037.
    • (2006) Cell , vol.124 , pp. 393-405
    • Andersson, E.1    Tryggvason, U.2    Deng, Q.3    Friling, S.4    Alekseenko, Z.5
  • 6
    • 34548186224 scopus 로고    scopus 로고
    • Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner
    • doi:10.1242/dev.000141
    • Ferri ALM, Lin W, Mavromatakis YE, Wang JC, Sasaki H, et al. (2007) Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner. Development 134: 2761-2769 doi:10.1242/dev.000141.
    • (2007) Development , vol.134 , pp. 2761-2769
    • Ferri, A.L.M.1    Lin, W.2    Mavromatakis, Y.E.3    Wang, J.C.4    Sasaki, H.5
  • 7
    • 0032584085 scopus 로고    scopus 로고
    • Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons
    • Saucedo-Cardenas O, Quintana-Hau JD, Le WD, Smidt MP, Cox JJ, et al. (1998) Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci USA 95: 4013-4018.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4013-4018
    • Saucedo-Cardenas, O.1    Quintana-Hau, J.D.2    Le, W.D.3    Smidt, M.P.4    Cox, J.J.5
  • 8
    • 0030722332 scopus 로고    scopus 로고
    • A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons
    • Smidt MP, Van Schaick HS, Lanctôt C, Tremblay JJ, Cox JJ, et al. (1997) A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc Natl Acad Sci USA 94: 13305-13310.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13305-13310
    • Smidt, M.P.1    Van Schaick, H.S.2    Lanctôt, C.3    Tremblay, J.J.4    Cox, J.J.5
  • 9
    • 0034034739 scopus 로고    scopus 로고
    • A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
    • doi:10.1038/73902
    • Smidt MP, Asbreuk CH, Cox JJ, Chen H, Johnson RL, et al. (2000) A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat Neurosci 3: 337-341 doi:10.1038/73902.
    • (2000) Nat Neurosci , vol.3 , pp. 337-341
    • Smidt, M.P.1    Asbreuk, C.H.2    Cox, J.J.3    Chen, H.4    Johnson, R.L.5
  • 10
    • 5444223350 scopus 로고    scopus 로고
    • Homeobox gene Pitx3 and its role in the development of dopamine neurons of the substantia nigra
    • doi:10.1007/s00441-004-0943-1
    • Smidt MP, Smits SM, Burbach JPH, (2004) Homeobox gene Pitx3 and its role in the development of dopamine neurons of the substantia nigra. Cell Tissue Res 318: 35-43 doi:10.1007/s00441-004-0943-1.
    • (2004) Cell Tissue Res , vol.318 , pp. 35-43
    • Smidt, M.P.1    Smits, S.M.2    Burbach, J.P.H.3
  • 11
    • 33244496187 scopus 로고    scopus 로고
    • Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons
    • doi:10.1242/dev.02223
    • Kele J, Simplicio N, Ferri ALM, Mira H, Guillemot F, et al. (2006) Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 133: 495-505 doi:10.1242/dev.02223.
    • (2006) Development , vol.133 , pp. 495-505
    • Kele, J.1    Simplicio, N.2    Ferri, A.L.M.3    Mira, H.4    Guillemot, F.5
  • 12
    • 33750372829 scopus 로고    scopus 로고
    • The role of Pitx3 in survival of midbrain dopaminergic neurons
    • Smits SM, Smidt MP (2006) The role of Pitx3 in survival of midbrain dopaminergic neurons. J Neural Transm Suppl: 57-60.
    • (2006) J Neural Transm Suppl , pp. 57-60
    • Smits, S.M.1    Smidt, M.P.2
  • 13
    • 34848896595 scopus 로고    scopus 로고
    • Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells
    • doi:10.1242/dev.02879
    • Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, et al. (2007) Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development 134: 3213-3225 doi:10.1242/dev.02879.
    • (2007) Development , vol.134 , pp. 3213-3225
    • Ono, Y.1    Nakatani, T.2    Sakamoto, Y.3    Mizuhara, E.4    Minaki, Y.5
  • 14
    • 2542628846 scopus 로고    scopus 로고
    • Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain
    • doi:10.1242/dev.01107
    • Puelles E, Annino A, Tuorto F, Usiello A, Acampora D, et al. (2004) Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development 131: 2037-2048 doi:10.1242/dev.01107.
    • (2004) Development , vol.131 , pp. 2037-2048
    • Puelles, E.1    Annino, A.2    Tuorto, F.3    Usiello, A.4    Acampora, D.5
  • 15
    • 70649111336 scopus 로고    scopus 로고
    • Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway
    • doi:10.1016/j.stem.2009.09.015
    • Chung S, Leung A, Han B-S, Chang M-Y, Moon J-I, et al. (2009) Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway. Cell Stem Cell 5: 646-658 doi:10.1016/j.stem.2009.09.015.
    • (2009) Cell Stem Cell , vol.5 , pp. 646-658
    • Chung, S.1    Leung, A.2    Han, B.-S.3    Chang, M.-Y.4    Moon, J.-I.5
  • 16
    • 80052382699 scopus 로고    scopus 로고
    • Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors
    • doi:10.1523/JNEUROSCI.1077-11.2011
    • Yan CH, Levesque M, Claxton S, Johnson RL, Ang S-L, (2011) Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. J Neurosci 31: 12413-12425 doi:10.1523/JNEUROSCI.1077-11.2011.
    • (2011) J Neurosci , vol.31 , pp. 12413-12425
    • Yan, C.H.1    Levesque, M.2    Claxton, S.3    Johnson, R.L.4    Ang, S.-L.5
  • 17
    • 79960640766 scopus 로고    scopus 로고
    • Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development
    • doi:10.1242/dev.065482
    • Deng Q, Andersson E, Hedlund E, Alekseenko Z, Coppola E, et al. (2011) Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development. Development 138: 3399-3408 doi:10.1242/dev.065482.
    • (2011) Development , vol.138 , pp. 3399-3408
    • Deng, Q.1    Andersson, E.2    Hedlund, E.3    Alekseenko, Z.4    Coppola, E.5
  • 18
    • 0034677480 scopus 로고    scopus 로고
    • The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS
    • doi:10.1038/35001573
    • Millonig JH, Millen KJ, Hatten ME, (2000) The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS. Nature 403: 764-769 doi:10.1038/35001573.
    • (2000) Nature , vol.403 , pp. 764-769
    • Millonig, J.H.1    Millen, K.J.2    Hatten, M.E.3
  • 19
    • 33749581676 scopus 로고    scopus 로고
    • Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene
    • doi:10.1007/s00335-006-0033-7
    • Chizhikov V, Steshina E, Roberts R, Ilkin Y, Washburn L, et al. (2006) Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene. Mamm Genome 17: 1025-1032 doi:10.1007/s00335-006-0033-7.
    • (2006) Mamm Genome , vol.17 , pp. 1025-1032
    • Chizhikov, V.1    Steshina, E.2    Roberts, R.3    Ilkin, Y.4    Washburn, L.5
  • 20
    • 35348913170 scopus 로고    scopus 로고
    • Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb
    • doi:10.1016/j.ydbio.2007.08.023
    • Nam J-S, Park E, Turcotte TJ, Palencia S, Zhan X, et al. (2007) Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb. Dev Biol 311: 124-135 doi:10.1016/j.ydbio.2007.08.023.
    • (2007) Dev Biol , vol.311 , pp. 124-135
    • Nam, J.-S.1    Park, E.2    Turcotte, T.J.3    Palencia, S.4    Zhan, X.5
  • 21
    • 1642363250 scopus 로고    scopus 로고
    • Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3
    • doi:10.1242/dev.01022
    • Smidt MP, Smits SM, Bouwmeester H, Hamers FPT, Van der Linden AJA, et al. (2004) Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3. Development 131: 1145-1155 doi:10.1242/dev.01022.
    • (2004) Development , vol.131 , pp. 1145-1155
    • Smidt, M.P.1    Smits, S.M.2    Bouwmeester, H.3    Hamers, F.P.T.4    Van der Linden, A.J.A.5
  • 22
    • 0242708712 scopus 로고    scopus 로고
    • Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons
    • Smits SM, Ponnio T, Conneely OM, Burbach JPH, Smidt MP, (2003) Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. Eur J Neurosci 18: 1731-1738.
    • (2003) Eur J Neurosci , vol.18 , pp. 1731-1738
    • Smits, S.M.1    Ponnio, T.2    Conneely, O.M.3    Burbach, J.P.H.4    Smidt, M.P.5
  • 24
    • 5444231261 scopus 로고    scopus 로고
    • Age-associated alteration of gene expression patterns in mouse oocytes
    • doi:10.1093/hmg/ddh241
    • Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, et al. (2004) Age-associated alteration of gene expression patterns in mouse oocytes. Hum Mol Genet 13: 2263-2278 doi:10.1093/hmg/ddh241.
    • (2004) Hum Mol Genet , vol.13 , pp. 2263-2278
    • Hamatani, T.1    Falco, G.2    Carter, M.G.3    Akutsu, H.4    Stagg, C.A.5
  • 25
    • 1342294092 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
    • Yang YH, Dudoit S, Luu P, Lin DM, Peng V, et al. (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
    • (2002) Nucleic Acids Res , vol.30
    • Yang, Y.H.1    Dudoit, S.2    Luu, P.3    Lin, D.M.4    Peng, V.5
  • 26
    • 0036513412 scopus 로고    scopus 로고
    • Large-Scale Analysis of Gene Expression Profiles
    • doi:10.1093/bib/3.1.7
    • Wu TD, (2002) Large-Scale Analysis of Gene Expression Profiles. Brief Bioinform 3: 7-17 doi:10.1093/bib/3.1.7.
    • (2002) Brief Bioinform , vol.3 , pp. 7-17
    • Wu, T.D.1
  • 27
    • 58549091700 scopus 로고    scopus 로고
    • Expression of the LIM-homeodomain gene Lmx1a in the postnatal mouse central nervous system
    • doi:10.1016/j.brainresbull.2008.12.001
    • Zou H-L, Su C-J, Shi M, Zhao G-Y, Li Z-Y, et al. (2009) Expression of the LIM-homeodomain gene Lmx1a in the postnatal mouse central nervous system. Brain Research Bulletin 78: 306-312 doi:10.1016/j.brainresbull.2008.12.001.
    • (2009) Brain Research Bulletin , vol.78 , pp. 306-312
    • Zou, H.-L.1    Su, C.-J.2    Shi, M.3    Zhao, G.-Y.4    Li, Z.-Y.5
  • 28
    • 0042926877 scopus 로고    scopus 로고
    • Forebrain gene expression domains and the evolving prosomeric model
    • Puelles L, Rubenstein JLR, (2003) Forebrain gene expression domains and the evolving prosomeric model. Trends Neurosci 26: 469-476.
    • (2003) Trends Neurosci , vol.26 , pp. 469-476
    • Puelles, L.1    Rubenstein, J.L.R.2
  • 29
    • 77649182947 scopus 로고    scopus 로고
    • Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon
    • doi:10.1016/j.ydbio.2009.12.017
    • Nakatani T, Kumai M, Mizuhara E, Minaki Y, Ono Y, (2010) Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon. Dev Biol 339: 101-113 doi:10.1016/j.ydbio.2009.12.017.
    • (2010) Dev Biol , vol.339 , pp. 101-113
    • Nakatani, T.1    Kumai, M.2    Mizuhara, E.3    Minaki, Y.4    Ono, Y.5
  • 30
    • 84872152624 scopus 로고    scopus 로고
    • Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons
    • doi:10.1111/ejn.12022
    • Hoekstra EJ, Von Oerthel L, Van der Linden AJA, Schellevis RD, Scheppink G, et al. (2013) Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons. Eur J Neurosci 37: 23-32 doi:10.1111/ejn.12022.
    • (2013) Eur J Neurosci , vol.37 , pp. 23-32
    • Hoekstra, E.J.1    Von Oerthel, L.2    Van der Linden, A.J.A.3    Schellevis, R.D.4    Scheppink, G.5
  • 31
    • 34547816228 scopus 로고    scopus 로고
    • Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency
    • doi:10.1242/dev.02865
    • Jacobs FMJ, Smits SM, Noorlander CW, Von Oerthel L, Van der Linden AJA, et al. (2007) Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. Development 134: 2673-2684 doi:10.1242/dev.02865.
    • (2007) Development , vol.134 , pp. 2673-2684
    • Jacobs, F.M.J.1    Smits, S.M.2    Noorlander, C.W.3    Von Oerthel, L.4    Van der Linden, A.J.A.5
  • 32
    • 69649095128 scopus 로고    scopus 로고
    • Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons
    • doi:10.1242/dev.037556
    • Jacobs FMJ, Van der Linden AJA, Wang Y, Von Oerthel L, Sul HS, et al. (2009) Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons. Development 136: 2363-2373 doi:10.1242/dev.037556.
    • (2009) Development , vol.136 , pp. 2363-2373
    • Jacobs, F.M.J.1    Van der Linden, A.J.A.2    Wang, Y.3    Von Oerthel, L.4    Sul, H.S.5
  • 33
    • 80755152950 scopus 로고    scopus 로고
    • Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons
    • doi:10.1242/dev.071704
    • Jacobs FMJ, Veenvliet JV, Almirza WH, Hoekstra EJ, Von Oerthel L, et al. (2011) Retinoic acid-dependent and-independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons. Development 138: 5213-5222 doi:10.1242/dev.071704.
    • (2011) Development , vol.138 , pp. 5213-5222
    • Jacobs, F.M.J.1    Veenvliet, J.V.2    Almirza, W.H.3    Hoekstra, E.J.4    Von Oerthel, L.5
  • 34
    • 84855895468 scopus 로고    scopus 로고
    • Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells
    • doi:10.1089/hum.2011.054
    • Sánchez-Danés A, Consiglio A, Richaud Y, Rodríguez-Pizà I, Dehay B, et al. (2012) Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells. Hum Gene Ther 23: 56-69 doi:10.1089/hum.2011.054.
    • (2012) Hum Gene Ther , vol.23 , pp. 56-69
    • Sánchez-Danés, A.1    Consiglio, A.2    Richaud, Y.3    Rodríguez-Pizà, I.4    Dehay, B.5
  • 35
    • 66149085781 scopus 로고    scopus 로고
    • Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
    • doi:10.1073/pnas.0902396106
    • Friling S, Andersson E, Thompson LH, Jönsson ME, Hebsgaard JB, et al. (2009) Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc Natl Acad Sci USA 106: 7613-7618 doi:10.1073/pnas.0902396106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7613-7618
    • Friling, S.1    Andersson, E.2    Thompson, L.H.3    Jönsson, M.E.4    Hebsgaard, J.B.5
  • 36
    • 67549114835 scopus 로고    scopus 로고
    • Lentiviral delivery of LMX1a enhances dopaminergic phenotype in differentiated human bone marrow mesenchymal stem cells
    • doi:10.1089/scd.2008.0138
    • Barzilay R, Ben-Zur T, Bulvik S, Melamed E, Offen D, (2009) Lentiviral delivery of LMX1a enhances dopaminergic phenotype in differentiated human bone marrow mesenchymal stem cells. Stem Cells Dev 18: 591-601 doi:10.1089/scd.2008.0138.
    • (2009) Stem Cells Dev , vol.18 , pp. 591-601
    • Barzilay, R.1    Ben-Zur, T.2    Bulvik, S.3    Melamed, E.4    Offen, D.5
  • 37
    • 43649094851 scopus 로고    scopus 로고
    • Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3
    • doi:10.1523/JNEUROSCI.0311-08.2008
    • Roybon L, Hjalt T, Christophersen NS, Li J-Y, Brundin P, (2008) Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3. J Neurosci 28: 3644-3656 doi:10.1523/JNEUROSCI.0311-08.2008.
    • (2008) J Neurosci , vol.28 , pp. 3644-3656
    • Roybon, L.1    Hjalt, T.2    Christophersen, N.S.3    Li, J.-Y.4    Brundin, P.5
  • 38
    • 0344305420 scopus 로고    scopus 로고
    • Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice
    • doi:10.1016/S1044-7431(03)00207-0
    • Brandt MD, Jessberger S, Steiner B, Kronenberg G, Reuter K, et al. (2003) Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Molecular and Cellular Neuroscience 24: 603-613 doi:10.1016/S1044-7431(03)00207-0.
    • (2003) Molecular and Cellular Neuroscience , vol.24 , pp. 603-613
    • Brandt, M.D.1    Jessberger, S.2    Steiner, B.3    Kronenberg, G.4    Reuter, K.5
  • 39
    • 30744479491 scopus 로고    scopus 로고
    • Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains
    • doi:10.1096/fj.05-4707com
    • Niculescu MD, Craciunescu CN, Zeisel SH, (2006) Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J 20: 43-49 doi:10.1096/fj.05-4707com.
    • (2006) FASEB J , vol.20 , pp. 43-49
    • Niculescu, M.D.1    Craciunescu, C.N.2    Zeisel, S.H.3
  • 40
    • 67650921949 scopus 로고    scopus 로고
    • Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
    • doi:10.1073/pnas.0904715106
    • Khalil AM, Guttman M, Huarte M, Garber M, Raj A, et al. (2009) Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci U S A 106: 11667-11672 doi:10.1073/pnas.0904715106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11667-11672
    • Khalil, A.M.1    Guttman, M.2    Huarte, M.3    Garber, M.4    Raj, A.5
  • 41
    • 79953200121 scopus 로고    scopus 로고
    • A WNT/beta-catenin signaling activator, R-spondin, plays positive regulatory roles during skeletal myogenesis
    • doi:10.1074/jbc.M110.169391
    • Han XH, Jin Y-R, Seto M, Yoon JK, (2011) A WNT/beta-catenin signaling activator, R-spondin, plays positive regulatory roles during skeletal myogenesis. J Biol Chem 286: 10649-10659 doi:10.1074/jbc.M110.169391.
    • (2011) J Biol Chem , vol.286 , pp. 10649-10659
    • Han, X.H.1    Jin, Y.-R.2    Seto, M.3    Yoon, J.K.4
  • 42
    • 79952188806 scopus 로고    scopus 로고
    • The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal-mesenchymal interaction
    • doi:10.1016/j.ydbio.2011.01.004
    • Jin Y-R, Turcotte TJ, Crocker AL, Han XH, Yoon JK, (2011) The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal-mesenchymal interaction. Dev Biol 352: 1-13 doi:10.1016/j.ydbio.2011.01.004.
    • (2011) Dev Biol , vol.352 , pp. 1-13
    • Jin, Y.-R.1    Turcotte, T.J.2    Crocker, A.L.3    Han, X.H.4    Yoon, J.K.5
  • 43
    • 83555173407 scopus 로고    scopus 로고
    • Cellular signaling and biological functions of R-spondins
    • doi:10.1016/j.cellsig.2011.09.023
    • Yoon JK, Lee J-S, (2012) Cellular signaling and biological functions of R-spondins. Cell Signal 24: 369-377 doi:10.1016/j.cellsig.2011.09.023.
    • (2012) Cell Signal , vol.24 , pp. 369-377
    • Yoon, J.K.1    Lee, J.-S.2
  • 44
    • 62049086203 scopus 로고    scopus 로고
    • Craniofacial malformation in R-spondin2 knockout mice
    • doi:10.1016/j.bbrc.2009.02.066
    • Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, et al. (2009) Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun 381: 453-458 doi:10.1016/j.bbrc.2009.02.066.
    • (2009) Biochem Biophys Res Commun , vol.381 , pp. 453-458
    • Yamada, W.1    Nagao, K.2    Horikoshi, K.3    Fujikura, A.4    Ikeda, E.5
  • 45
    • 42549128765 scopus 로고    scopus 로고
    • R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
    • doi:10.1242/dev.013359
    • Bell SM, Schreiner CM, Wert SE, Mucenski ML, Scott WJ, et al. (2008) R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. Development 135: 1049-1058 doi:10.1242/dev.013359.
    • (2008) Development , vol.135 , pp. 1049-1058
    • Bell, S.M.1    Schreiner, C.M.2    Wert, S.E.3    Mucenski, M.L.4    Scott, W.J.5
  • 46
    • 33751547518 scopus 로고    scopus 로고
    • Dynamic expression of R-spondin family genes in mouse development
    • doi:10.1016/j.modgep.2006.08.006
    • Nam J-S, Turcotte TJ, Yoon JK, (2007) Dynamic expression of R-spondin family genes in mouse development. Gene Expression Patterns 7: 306-312 doi:10.1016/j.modgep.2006.08.006.
    • (2007) Gene Expression Patterns , vol.7 , pp. 306-312
    • Nam, J.-S.1    Turcotte, T.J.2    Yoon, J.K.3
  • 47
    • 48749104088 scopus 로고    scopus 로고
    • R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism
    • doi:10.1091/mbc.E08-02-0187
    • Kim K-A, Wagle M, Tran K, Zhan X, Dixon MA, et al. (2008) R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism. Mol Biol Cell 19: 2588-2596 doi:10.1091/mbc.E08-02-0187.
    • (2008) Mol Biol Cell , vol.19 , pp. 2588-2596
    • Kim, K.-A.1    Wagle, M.2    Tran, K.3    Zhan, X.4    Dixon, M.A.5
  • 48
    • 33744964431 scopus 로고    scopus 로고
    • Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
    • doi:10.1074/jbc.M508324200
    • Nam J-S, Turcotte TJ, Smith PF, Choi S, Yoon JK, (2006) Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem 281: 13247-13257 doi:10.1074/jbc.M508324200.
    • (2006) J Biol Chem , vol.281 , pp. 13247-13257
    • Nam, J.-S.1    Turcotte, T.J.2    Smith, P.F.3    Choi, S.4    Yoon, J.K.5
  • 49
    • 83555169992 scopus 로고    scopus 로고
    • Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells
    • doi:10.1002/jcp.22924
    • Klauzinska M, Baljinnyam B, Raafat A, Rodriguez-Canales J, Strizzi L, et al. (2012) Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells. Journal of Cellular Physiology 227: 1960-1971 doi:10.1002/jcp.22924.
    • (2012) Journal of Cellular Physiology , vol.227 , pp. 1960-1971
    • Klauzinska, M.1    Baljinnyam, B.2    Raafat, A.3    Rodriguez-Canales, J.4    Strizzi, L.5
  • 50
    • 5044244757 scopus 로고    scopus 로고
    • R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
    • doi:10.1016/j.devcel.2004.07.019
    • Kazanskaya O, Glinka A, Del Barco Barrantes I, Stannek P, Niehrs C, et al. (2004) R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Dev Cell 7: 525-534 doi:10.1016/j.devcel.2004.07.019.
    • (2004) Dev Cell , vol.7 , pp. 525-534
    • Kazanskaya, O.1    Glinka, A.2    Del Barco Barrantes, I.3    Stannek, P.4    Niehrs, C.5
  • 51
  • 52
    • 0036333208 scopus 로고    scopus 로고
    • A mitogen gradient of dorsal midline Wnts organizes growth in the CNS
    • Megason SG, McMahon AP, (2002) A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development 129: 2087-2098.
    • (2002) Development , vol.129 , pp. 2087-2098
    • Megason, S.G.1    McMahon, A.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.