Tetrahydrobiopterin, L-arginine and vitamin C actsynergistically to decrease oxidative stress, increase nitricoxide and improve blood flow after induction of hindlimbischemia in the rat.

Molecular medicine (Cambridge, Mass.)

Volumn 18, Issue , 2012, Pages 676-684

  Yan, Jinglian ^a   Tie, Guodong ^b   Messina, Louis M ^b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

5,6,7,8-TETRAHYDROBIOPTERIN; ANTIOXIDANT; ARGININE; ASCORBIC ACID; BIOPTERIN; CALCIUM; DRUG DERIVATIVE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; TETRAHYDROBIOPTERIN;

ANIMAL; ARTICLE; BLOOD FLOW; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; HINDLIMB; ISCHEMIA; MALE; METABOLISM; NECROSIS; ORAL DRUG ADMINISTRATION; OXIDATIVE STRESS; PATHOLOGY; RAT; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; ARGININE; ASCORBIC ACID; BIOPTERIN; CALCIUM; DRUG SYNERGISM; ENZYME ACTIVATION; HINDLIMB; ISCHEMIA; MALE; MUSCLE, SKELETAL; NECROSIS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW;

MLCS; MLOWN;

EID: 84884174658     PISSN: None     EISSN: 15283658     Source Type: Journal    
DOI: 10.2119/molmed.2011.00103     Document Type: Article

References (0)