Zein-based oral drug delivery system targeting activated macrophages

International Journal of Pharmaceutics

Volumn 454, Issue 1, 2013, Pages 388-393

  Lee, Sungmun ^a   Alwahab, Noaf Salah Ali ^a   Moazzam, Zainab Muhammad ^a  

^a KHALIFA UNIVERSITY   (United Arab Emirates)

Author keywords

Inflammatory disease; Oral drug delivery; Reactive oxygen species; Zein

Indexed keywords

FOLIC ACID; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ZEIN;

ARTICLE; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; IN VITRO STUDY; MACROPHAGE; MAIZE; NANOENCAPSULATION; ORAL DRUG ADMINISTRATION; PH; PHASE SEPARATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; SCANNING ELECTRON MICROSCOPY; TARGET CELL;

EID: 84884142101     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.07.026     Document Type: Article

References (21)

1. Chaptal, J., Jean, R., et al., 1957. Celiac disease caused by intolerance to gliadin from wheat, oats & milk products. Pediatrie 12, 737-747.
2. Chickering, D., Jacob, J., et al., 1996. Poly(fumaric-co-sebacic) microspheres as oral drug delivery systems. Biotechnol. Bioeng. 52, 96-101. (Pubitemid 26317943)
3. Cloarec, M., Caillard, P., et al., 2007. GliSODin, a vegetal sod with gliadin, as preventative agent vs. atherosclerosis, as confirmed with carotid ultrasound-B imaging. Eur. Ann. Allergy Clin. Immunol. 39, 45-50. (Pubitemid 46447668)
4. Cruz, M.E.M., Gaspar, M.M., et al., 2005. Liposomal superoxide dismutase and their use in the treatment of experimental arthritis. Method Enzymol. 391, 395-413. (Pubitemid 40254047)
5. Cuzzocrea, S., Thiemermann, C., et al., 2004. Potential therapeutic effect of antioxidant therapy in shock and inflammation. Curr. Med. Chem. 11, 1147-1162. (Pubitemid 38585059)
6. Cuzzocrea, S., 2006. Role of nitric oxide and reactive oxygen species in arthritis. Curr. Pharm. Des. 12, 3551-3570. (Pubitemid 44400492)
7. Estevez, A.G., Sampson, J.B., et al., 2000. Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal. Free Radic. Biol. Med. 28, 437-446. (Pubitemid 30110660)
8. Flohe, L., 1988. Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes. Mol. Cell. Biochem. 84, 123-131. (Pubitemid 19027100)
9. Hattori, Y., Sakaguchi, M., et al., 2006. Folate-linked lipid-based nanoparticles deliver a NF(B decoy into activated murine macrophage-like RAW264.7 cells. Biol. Pharm. Bull. 29, 1516-1520.
10. Hitchon, C.A., El-Gabalawy, H.S., 2004. Oxidation in rheumatoid arthritis. Arthritis Res. Ther. 6, 265-278. (Pubitemid 39490014)
11. Leamon, C.P., Low, P.S., 1991. Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc. Nat. Acad. Sci. U.S.A. 88, 5572-6557.
12. Leamon, C.P., Low, P.S., 1993. Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells. Biochem. J. 291, 855-860. (Pubitemid 23148463)
13. Lee, S., Murthy, N., 2007. Targeted delivery of catalase and superoxide dismutase to macrophages using folate. Biochem. Biophys. Res. Commun. 360, 275-279. (Pubitemid 46990354)
14. Liu, X., Sun, Q., et al., 2005. Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials 26, 109-115. (Pubitemid 38759476)
15. Luisa Corvo, M., Jorge, J.C., et al., 2002. Superoxide dismutase entrapped in long-circulating liposomes: formulation design and therapeutic activity in rat adjuvant arthritis. Biochim. Biophys. Acta 1564, 227-236.
16. Mates, J.M., Perez-Gomez, C., et al., 1999. Antioxidant enzymes and human diseases. Clin. Biochem. 32, 595-603. (Pubitemid 30039087)
17. Metheny, N.A., Stewart, B.J., et al., 1997. pH and concentrations of pepsin and trypsin in feeding tube aspirates as predictors of tube placement. J. Parenter. Enteral Nutr. 21, 279-285. (Pubitemid 27408646)
18. Pouton, C.W., 2000. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying drug delivery systems. Eur. J. Pharm. Sci. 11 (Suppl. 2), S93-S98.
19. Taysi, S., Polat, F., et al., 2002. Lipid peroxidation, some extracellular antioxidants, and antioxidant enzymes in serum of patients with rheumatoid arthritis. Rheumatol. Int. 21, 200-204. (Pubitemid 34209121)
20. Woodley, J.F., 1994. Enzymatic barriers for GI peptide and protein delivery. Crit. Rev. Ther. Drug Carrier Syst. 11, 61-95.
21. Wu, J., Liu, L., et al., 2004. Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice. Hepatology 40, 195-204. (Pubitemid 38868938)