Development and characterization of nanostructured mists with potential for actively targeting poorly water-soluble compounds into the lungs

Pharmaceutical Research

Volumn 30, Issue 10, 2013, Pages 2625-2639

  Nesamony, Jerry ^a   Kalra, Ashish ^a   Majrad, Mohamed S ^a   Boddu, Sai Hanuman Sagar ^a   Jung, Rose ^a   Williams, Frederick E ^b   Schnapp, Alaina M ^b   Nauli, Surya M ^b   Kalinoski, Andrea L ^b  

^a UNIVERSITY OF TOLEDO   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

cytotoxicity; in vitro permeability; nanoemulsions; poorly water soluble drug; pulmonary delivery system

Indexed keywords

CARBAMAZEPINE; CREMOPHOR; EMULSIFYING AGENT; MACROGOL 400; UNCLASSIFIED DRUG; WATER SOLUBLE DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG SOLUBILITY; EXCIPIENT COMPATIBILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INSTRUMENT STERILIZATION; LUNG PERMEABILITY; NANOEMULSION; NONHUMAN; PARTICLE SIZE; PERMEABILITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SWINE; TRANSMISSION ELECTRON MICROSCOPY; VALIDATION PROCESS; ZEBRA FISH; ZETA POTENTIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CARBAMAZEPINE; DRUG CARRIERS; DRUG COMPOUNDING; EMULSIONS; HELA CELLS; HUMANS; LUNG; MICE; NANOSTRUCTURES; NIH 3T3 CELLS; PARTICLE SIZE; PERMEABILITY; SOLUBILITY; SURFACE PROPERTIES; SWINE; WATER; ZEBRAFISH;

EID: 84883896915     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1088-2     Document Type: Article

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