Prediction of acute toxicity grade ≥ 3 in patients with locally advanced non-small-cell lung cancer receiving intensity modulated radiotherapy and concurrent low-dose cisplatin

Clinical Lung Cancer

Volumn 14, Issue 5, 2013, Pages 541-548

  Uyterlinde, Wilma ^a   Belderbos, José ^a   Baas, Claudia ^a   Van Werkhoven, Erik ^a   Knegjens, Joost ^a   Baas, Paul ^a   Smit, Arthur ^b   Rikers, Chris ^c   Van Den Heuvel, Michel ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^b Onze Lieve Vrouwen Gasthuis ^*  (Netherlands)

^c RED CROSS HOSPITAL   (Netherlands)

Author keywords

Chemoradiation; Comorbidity; IMRT; non small cell lung cancer; Toxicity

Indexed keywords

CISPLATIN;

ACUTE TOXICITY; ADULT; ADVANCED CANCER; AGED; ANOREXIA; ARTICLE; BLOOD TOXICITY; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; CHARLSON COMORBIDITY INDEX; DOSIMETRY; ESOPHAGITIS; FEMALE; GASTROINTESTINAL TOXICITY; GROUPS BY AGE; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LOW DRUG DOSE; LUNG NON SMALL CELL CANCER; LUNG TOXICITY; MAJOR CLINICAL STUDY; MALE; NAUSEA AND VOMITING; NEPHROTOXICITY; OVERALL SURVIVAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE DISTRIBUTION; SIDE EFFECT; WEIGHT REDUCTION;

CHEMORADIATION; COMORBIDITY; IMRT; NON-SMALL-CELL LUNG CANCER; TOXICITY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; CISPLATIN; COMORBIDITY; DOSE-RESPONSE RELATIONSHIP, DRUG; ESOPHAGUS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROSPECTIVE STUDIES; RADIOTHERAPY, INTENSITY-MODULATED; SURVIVAL RATE;

EID: 84883830249     PISSN: 15257304     EISSN: 19380690     Source Type: Journal    
DOI: 10.1016/j.cllc.2013.04.001     Document Type: Article

References (27)

1. C. Schaake-Koning, W. van den Bogaert, and O. Dalesio Effects of concomitant cisplatin and radiotherapy on inoperable non-small-cell lung cancer N Engl J Med 326 1992 524 530
2. A. Auperin, C. Le Pechoux, and E. Rolland Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer J Clin Oncol 28 2010 2181 2190
3. N. O'Rourke, I.F. Roque, and N. Farre Bernado Concurrent chemoradiotherapy in non-small cell lung cancer Cochrane Database Syst Rev 2010 CD002140
4. J. Belderbos, L. Uitterhoeve, and N. van Zandwijk Randomised trial of sequential versus concurrent chemo-radiotherapy in patients with inoperable non-small cell lung cancer (EORTC 08972-22973) Eur J Cancer 43 2007 114 121
5. M. Kwint, W. Uyterlinde, and C. Chen Acute esophagus toxicity in lung cancer patients after intensity modulated radiotherapy and concurrent chemotherapy Int J Radiat Oncol Biol Phys 84 2012 e223 e228
6. O. Chapet, E. Thomas, and M.L. Kessler Esophagus sparing with IMRT in lung tumor irradiation: an EUD-based optimization technique Int J Radiat Oncol Biol Phys 63 2005 179 187
7. M. Schwarz, L.J. Bos, and B.J. Mijnheer Importance of accurate dose calculations outside segment edges in intensity modulated radiotherapy treatment planning Radiother Oncol 69 2003 305 314
8. I.S. Grills, D. Yan, and A.A. Martinez Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer: a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal irradiation Int J Radiat Oncol Biol Phys 57 2003 875 890
9. D. De Ruysscher, A. Botterweck, and M. Dirx Eligibility for concurrent chemotherapy and radiotherapy of locally advanced lung cancer patients: a prospective, population-based study Ann Oncol 20 2009 98 102
10. U. Kefeli, S. Kaya, and B.O. Ustaalioglu Prognostic factors in elderly patients with non-small cell lung cancer: a two-center experience Med Oncol 28 2011 661 666
11. P. Baas, J.S. Belderbos, and M.M. van den Heuvel Chemoradiation therapy in nonsmall cell lung cancer Curr Opin Oncol 23 2011 140 149
12. P. McCloskey, B. Balduyck, and P.E. Van Schil Radical treatment of non-small cell lung cancer during the last 5 years Eur J Cancer 49 2013 1555 1564
13. J.W. Wolthaus, C. Schneider, and J.J. Sonke Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients Int J Radiat Oncol Biol Phys 65 2006 1560 1571
14. J. Belderbos, W. Heemsbergen, and M. Hoogeman Acute esophageal toxicity in non-small cell lung cancer patients after high dose conformal radiotherapy Radiother Oncol 75 2005 157 164
15. M.E. Charlson, P. Pompei, and K.L. Ales A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chronic Dis 40 1987 373 383
16. O. Birim, A.P. Kappetein, and M. Waleboer Long-term survival after non-small cell lung cancer surgery: development and validation of a prognostic model with a preoperative and postoperative mode J Thorac Cardiovasc Surg 132 2006 491 498
17. W. Jacot, B. Colinet, and D. Bertrand Quality of life and comorbidity score as prognostic determinants in non-small-cell lung cancer patients Ann Oncol 19 2008 1458 1464
18. E.C. Phernambucq, F.O. Spoelstra, and W.F. Verbakel Outcomes of concurrent chemoradiotherapy in patients with stage III non-small-cell lung cancer and significant comorbidity Ann Oncol 22 2011 132 138
19. J. Belderbos, and J.J. Sonke State-of-the-art lung cancer radiation therapy Expert Rev Anticancer Ther 9 2009 1353 1363
20. F. Reboul, Y. Brewer, and P. Vincent Concurrent cisplatin, etoposide, and radiotherapy for unresectable stage III nonsmall cell lung cancer: a phase II study Int J Radiat Oncol Biol Phys 35 1996 343 350
21. J.G. Rosenman, J.S. Halle, and M.A. Socinski High-dose conformal radiotherapy for treatment of stage IIIA/IIIB non-small-cell lung cancer: technical issues and results of a phase I/II trial Int J Radiat Oncol Biol Phys 54 2002 348 356
22. C. Pallares, J. Capdevila, and A. Paredes Induction chemotherapy with paclitaxel plus carboplatin followed by paclitaxel with concurrent radiotherapy in stage IIIB non-small-cell lung cancer (NSCLC) patients: a phase II trial Lung Cancer 58 2007 238 245
23. A. Hallqvist, G. Wagenius, and H. Rylander Concurrent cetuximab and radiotherapy after docetaxel-cisplatin induction chemotherapy in stage III NSCLC: satellite-a phase II study from the Swedish Lung Cancer Study Group Lung Cancer 71 2011 166 172
24. N. O'Rourke, and F. Macbeth Is concurrent chemoradiation the standard of care for locally advanced non-small cell lung cancer? A review of guidelines and evidence Clin Oncol (R Coll Radiol) 22 2010 347 355
25. A.L. Uitterhoeve, J.S. Belderbos, and M.G. Koolen Toxicity of high-dose radiotherapy combined with daily cisplatin in non-small cell lung cancer: results of the EORTC 08912 phase I/II study. European Organization for Research and Treatment of Cancer Eur J Cancer 36 2000 592 600
26. M.M. Hochstenbag, A. Twijnstra, and P. Hofman MR-imaging of the brain of neurologic asymptomatic patients with large cell or adenocarcinoma of the lung. Does it influence prognosis and treatment? Lung Cancer 42 2003 189 193
27. W. van Elmpt, D. De Ruysscher, and A. van der Salm The PET-boost randomised phase II dose-escalation trial in non-small cell lung cancer Radiother Oncol 104 2012 67 71