Three dimensional tissue based digital microfluidic screening platform

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

Volumn 3, Issue , 2011, Pages 1545-1547

  George, S M ^a   Moon, H ^a  

^a University of Texas at Arlington   (United States)

Author keywords

3D tissue engineering; Digital microfluidics; Drug screening; EWOD

Indexed keywords

3-DIMENSIONAL; 3D TISSUE ENGINEERINGS; CULTURE SYSTEMS; DRUG SCREENING; ELECTRO-WETTING ON DIELECTRICS; EWOD; HIGH THROUGHPUT; PHARMACEUTICAL DRUGS;

CELL CULTURE; DIELECTRIC MATERIALS; DIGITAL MICROFLUIDICS; THREE DIMENSIONAL; TISSUE ENGINEERING; WETTING;

TISSUE;

EID: 84883823209     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (8)

1. J.H. Sung, C. Kam and M.L. Shuler, "A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip,", Lab Chip 10 (2010), 446, (2010)
2. J. Lee, M. Cuddihy, N. Kotov, "Three-dimensional cell culture matrices: State of the art,", Tissue Eng. B. 14: 61, (2008)
3. J. Lii, et al, "Real-time microfluidic system for studying mammalian cells in 3D microenvironments,", Anal. Chem. 80, 3640-3647, (2008)
4. J.H. Sung and M.L. Shuler, "A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs,", Lab Chip 9, 1385, (2009)
5. J. Lee, H. Moon, et al., "Electrowetting and electrowetting-on- dielectric for microscale liquid handling,", Sensors and Actuators, A95, 259. (2002)
6. H. Moon, A. Wheeler, et al., "An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS,", Lab Chip 6, 1213 (2006).
7. I. Barbulovic-Nad, et al, "A microfluidic platform for complete mammalian cell culture,", Lab Chip, 10, 1536 (2010).
8. P. Wijethunga, Y. Nanayakkara et al., "On-Chip Drop-to-Drop Liquid Microextraction Coupled with Real-Time Concentration Monitoring Technique,", Analytical Chemistry, 83(5), 1658-1664, (2011)