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Volumn 3, Issue 10, 2013, Pages 834-840

Review on pharmacological and toxicologyical effects of oleum azadirachti oil

Author keywords

Azadirachta indica; Meliaceae; Oleum azadirachti; Pharmacology; Toxicology

Indexed keywords

17 HYDROXYDIRADIONE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AZADIRACHTIN; AZADIRIADIONE; AZADIRONE; DEACETYLNIMBIN; EPOXYAZADIRADIONE; ESSENTIAL OIL; ESTROGEN; GAMMA INTERFERON; GEDUNIN; MAHMOODIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NIMBIDIN; NIMBIN; OLEUM AZADIRACHTI OIL; ORAL ANTIDIABETIC AGENT; PHENYLBUTAZONE; PLACEBO; PROGESTERONE; SALANNIN; TERPENE DERIVATIVE; TETANUS ANTIBODY; TETRANOTRITERPENE; UNCLASSIFIED DRUG;

EID: 84883816532     PISSN: 22211691     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2221-1691(13)60165-3     Document Type: Article
Times cited : (25)

References (58)
  • 1
    • 84883761776 scopus 로고
    • Scientific, Technical and Research Commission, Organization of African Unity, Lagos
    • Scientific, Technical and Research Commission African pharmacopoeia 1985, Vol. 1:59-67. Organization of African Unity, Lagos.
    • (1985) African pharmacopoeia , vol.1 , pp. 59-67
  • 2
    • 84883813600 scopus 로고
    • Central Council for Research in Unani Medicine
    • Ministry of Health and Family Welfare, New Delhi
    • Central Council for Research in Unani Medicine Standardization of single drugs of Unani medicine - Part II 1987, 164-169. Ministry of Health and Family Welfare, New Delhi.
    • (1987) Standardization of single drugs of Unani medicine - Part II , pp. 164-169
  • 3
    • 84883776420 scopus 로고
    • Policy Research and Strategic Planning Institute (Council for Scientific and Industrial Research (Ghana)
    • Policy Research and Strategic Planning Institute (PORSPI), Accra
    • Policy Research and Strategic Planning Institute (Council for Scientific and Industrial Research (Ghana) Ghana herbal pharmacopoeia 1992, 91-95. Policy Research and Strategic Planning Institute (PORSPI), Accra.
    • (1992) Ghana herbal pharmacopoeia , pp. 91-95
  • 5
    • 84883764777 scopus 로고
    • Orient Longman, New Delhi
    • Indian medicinal plants 1971, Vol. I:204-209. Orient Longman, New Delhi.
    • (1971) Indian medicinal plants , vol.1 , pp. 204-209
  • 8
    • 84883777583 scopus 로고    scopus 로고
    • Ministry of Health and Family Welfare
    • Ministry of Health and Family Welfare, Department of Indian System of Medicine and Homeopathy, New Delhi
    • Ministry of Health and Family Welfare The Ayurvedic pharmacopoeia of India. Part I 2001, Vol. II:116-124. Ministry of Health and Family Welfare, Department of Indian System of Medicine and Homeopathy, New Delhi.
    • (2001) The Ayurvedic pharmacopoeia of India. Part I , vol.2 , pp. 116-124
  • 9
    • 0004298781 scopus 로고    scopus 로고
    • University of Illinois at Chicago, Chicago (IL), [Cited 2013 Feb 12]. N.R. Farnsworth (Ed.)
    • NAPRALERT database 2001, University of Illinois at Chicago, Chicago (IL), [Cited 2013 Feb 12]. http://napralert.org/, N.R. Farnsworth (Ed.).
    • (2001) NAPRALERT database
  • 10
    • 13044309823 scopus 로고
    • Centre for Indian Knowledge Systems and Research Foundation for Science, Technology and Natural Resource Policy, New Delhi
    • Vijayalakshmi K, Radha KS, Shiva V Neem: a user's manual 1995, 109-122. Centre for Indian Knowledge Systems and Research Foundation for Science, Technology and Natural Resource Policy, New Delhi.
    • (1995) Neem: a user's manual , pp. 109-122
    • Vijayalakshmi, K.1    Radha, K.S.2    Shiva, V.3
  • 11
    • 84883757466 scopus 로고    scopus 로고
    • World Health Organization Regional Office for the Western Pacific
    • World Health Organization Regional Office for the Western Pacific, Manila
    • World Health Organization Regional Office for the Western Pacific Medicinal plants in the South Pacific 1998, 202-212. World Health Organization Regional Office for the Western Pacific, Manila.
    • (1998) Medicinal plants in the South Pacific , pp. 202-212
  • 13
    • 0001805675 scopus 로고
    • Biologically active ingredients: Azadirachtin and other triterpenoids
    • VCH, Weinheim, H. Schmutterre (Ed.)
    • Kraus W Biologically active ingredients: Azadirachtin and other triterpenoids. The neem tree: Azadirachta indica A. Juss. and other meliaceous plants 1995, 48-57. VCH, Weinheim. H. Schmutterre (Ed.).
    • (1995) The neem tree: Azadirachta indica A. Juss. and other meliaceous plants , pp. 48-57
    • Kraus, W.1
  • 14
    • 0032613516 scopus 로고    scopus 로고
    • Chemistry of the neem tree (Azadirachta indica A. Juss.)
    • Akhila A, Rani K Chemistry of the neem tree (Azadirachta indica A. Juss.). Fortschr Chem Org Naturst 1999, 78:47-149.
    • (1999) Fortschr Chem Org Naturst , vol.78 , pp. 47-149
    • Akhila, A.1    Rani, K.2
  • 15
    • 3042732319 scopus 로고    scopus 로고
    • Analysis of neem oils by LC-MS and degradation kinetics of azadirachtin-A in a controlled environment. Characterization of degradation products by HPLC-MS-MS
    • Barrek S, Paisse O, Grenier-Loustalot MF Analysis of neem oils by LC-MS and degradation kinetics of azadirachtin-A in a controlled environment. Characterization of degradation products by HPLC-MS-MS. Anal Bioanal Chem 2004, 378(3):753-763.
    • (2004) Anal Bioanal Chem , vol.378 , Issue.3 , pp. 753-763
    • Barrek, S.1    Paisse, O.2    Grenier-Loustalot, M.F.3
  • 16
    • 0037433121 scopus 로고    scopus 로고
    • Variability in neem (Azadirachta indica) with respect to azadirachtin content
    • Sidhu OP, Kumar V, Behl HM Variability in neem (Azadirachta indica) with respect to azadirachtin content. J Agric Food Chem 2003, 51(4):910-915.
    • (2003) J Agric Food Chem , vol.51 , Issue.4 , pp. 910-915
    • Sidhu, O.P.1    Kumar, V.2    Behl, H.M.3
  • 17
    • 84883793446 scopus 로고    scopus 로고
    • The clinical studies on contraceptive effect of Nimba taila
    • Schawat D, Tyagi RK, Kishore P The clinical studies on contraceptive effect of Nimba taila. J Res Ayurveda Siddha 1998, 19:1-8.
    • (1998) J Res Ayurveda Siddha , vol.19 , pp. 1-8
    • Schawat, D.1    Tyagi, R.K.2    Kishore, P.3
  • 18
    • 0029362022 scopus 로고
    • Use of neem oil as a mosquito repellent in tribal villages of Mandla District, Madhya Pradesh
    • Mishra AK, Singh N, Sharma VP Use of neem oil as a mosquito repellent in tribal villages of Mandla District, Madhya Pradesh. Indian J Malariol 1995, 32(3):99-103.
    • (1995) Indian J Malariol , vol.32 , Issue.3 , pp. 99-103
    • Mishra, A.K.1    Singh, N.2    Sharma, V.P.3
  • 19
    • 30844438912 scopus 로고    scopus 로고
    • Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world
    • Isman MB Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world. Annu Rev Entomol 2006, 51:45-66.
    • (2006) Annu Rev Entomol , vol.51 , pp. 45-66
    • Isman, M.B.1
  • 20
    • 0029072411 scopus 로고
    • Clinical trial with praneem polyherbal cream in patients with abnormal vaginal discharge due to microbial infections
    • Mittal A, Kapur S, Garg S, Pharma M, Upadhyay SN, Suri S, et al. Clinical trial with praneem polyherbal cream in patients with abnormal vaginal discharge due to microbial infections. Aust N Z J Obstet Gynecol 1995, 35(2):190-191.
    • (1995) Aust N Z J Obstet Gynecol , vol.35 , Issue.2 , pp. 190-191
    • Mittal, A.1    Kapur, S.2    Garg, S.3    Pharma, M.4    Upadhyay, S.N.5    Suri, S.6
  • 22
    • 0028942496 scopus 로고
    • Safety evaluation of Azadirachta indica seed oil, a herbal wound dressing agent
    • Tandan SK, Gupta S, Chandra S, Lal J, Singh R Safety evaluation of Azadirachta indica seed oil, a herbal wound dressing agent. Fitoterapia 1995, 66:69-72.
    • (1995) Fitoterapia , vol.66 , pp. 69-72
    • Tandan, S.K.1    Gupta, S.2    Chandra, S.3    Lal, J.4    Singh, R.5
  • 23
    • 0027416997 scopus 로고
    • Toxicological studies on debitterized neem oil (Azadirachta indica)
    • Chinnasamy N, Harishankar N, Kumar PU Toxicological studies on debitterized neem oil (Azadirachta indica). Food Chem Toxicol 1993, 31(4):297-301.
    • (1993) Food Chem Toxicol , vol.31 , Issue.4 , pp. 297-301
    • Chinnasamy, N.1    Harishankar, N.2    Kumar, P.U.3
  • 24
    • 3242671179 scopus 로고
    • Antifertility effects of Azadirachta indica oil administered per os to female albino rats on selected days of pregnancy
    • Lal R, Gandhi M, Sankaranarayanan A, Mathur VS, Sharma PL Antifertility effects of Azadirachta indica oil administered per os to female albino rats on selected days of pregnancy. Fitoterapia 1987, 58(4):239-242.
    • (1987) Fitoterapia , vol.58 , Issue.4 , pp. 239-242
    • Lal, R.1    Gandhi, M.2    Sankaranarayanan, A.3    Mathur, V.S.4    Sharma, P.L.5
  • 26
    • 60749104678 scopus 로고    scopus 로고
    • Toxicity of botanical formulations to nursery-infesting white grubs (Coleoptera: Scarabaeidae)
    • Ranger CM, Reding ME, Oliver JB, Moyseenko JJ, Youssef NN Toxicity of botanical formulations to nursery-infesting white grubs (Coleoptera: Scarabaeidae). J Econ Entomol 2009, 102(1):304-308.
    • (2009) J Econ Entomol , vol.102 , Issue.1 , pp. 304-308
    • Ranger, C.M.1    Reding, M.E.2    Oliver, J.B.3    Moyseenko, J.J.4    Youssef, N.N.5
  • 27
    • 0030069025 scopus 로고    scopus 로고
    • Termination of pregnancy in rodents by oral administration of praneem, a purified neem seed extract
    • Mukherjee S, Talwar GP Termination of pregnancy in rodents by oral administration of praneem, a purified neem seed extract. Am J Reprod Immunol 1996, 35(1):51-56.
    • (1996) Am J Reprod Immunol , vol.35 , Issue.1 , pp. 51-56
    • Mukherjee, S.1    Talwar, G.P.2
  • 28
    • 0029889737 scopus 로고    scopus 로고
    • Purified neem (Azadirachta indica) seed extracts (Praneem) abrogate pregnancy in primates
    • Mukherjee S, Lohiya NK, Pal R, Sharma MG, Talwar GP Purified neem (Azadirachta indica) seed extracts (Praneem) abrogate pregnancy in primates. Contraception 1996, 53(6):375-378.
    • (1996) Contraception , vol.53 , Issue.6 , pp. 375-378
    • Mukherjee, S.1    Lohiya, N.K.2    Pal, R.3    Sharma, M.G.4    Talwar, G.P.5
  • 29
    • 0025648085 scopus 로고
    • Antifertility effects of neem (Azadirachta indica) oil by single intrauterine administration: a novel method of contraception
    • Upadhyay SN, Kaushic C, Talwar GP Antifertility effects of neem (Azadirachta indica) oil by single intrauterine administration: a novel method of contraception. Proc Biol Sci 1990, 242(1305):175-179.
    • (1990) Proc Biol Sci , vol.242 , Issue.1305 , pp. 175-179
    • Upadhyay, S.N.1    Kaushic, C.2    Talwar, G.P.3
  • 30
    • 0028210832 scopus 로고
    • Long-term contraceptive effects of intrauterine neem treatment (IUNT) in bonnet monkeys: an alternate to intrauterine contraceptive devices (IUCD)
    • Upadhyay SN, Dhawan S, Talwar GP Long-term contraceptive effects of intrauterine neem treatment (IUNT) in bonnet monkeys: an alternate to intrauterine contraceptive devices (IUCD). Contraception 1994, 49(2):161-169.
    • (1994) Contraception , vol.49 , Issue.2 , pp. 161-169
    • Upadhyay, S.N.1    Dhawan, S.2    Talwar, G.P.3
  • 31
    • 0027265534 scopus 로고
    • Antifertility effects of neem (Azadirachta indica) oil in male rats by single intra-vas administration: an alternate approach to vasectomy
    • Upadhyay SN, Dhawan S, Talwar GP Antifertility effects of neem (Azadirachta indica) oil in male rats by single intra-vas administration: an alternate approach to vasectomy. J Androl 1993, 14(4):275-281.
    • (1993) J Androl , vol.14 , Issue.4 , pp. 275-281
    • Upadhyay, S.N.1    Dhawan, S.2    Talwar, G.P.3
  • 32
    • 0023898781 scopus 로고
    • Non-hormonal post-coital contraceptive action of neem oil in rats
    • Prakash AO, Tewari RK, Mathur R Non-hormonal post-coital contraceptive action of neem oil in rats. J Ethnopharmacol 1988, 23(1):53-59.
    • (1988) J Ethnopharmacol , vol.23 , Issue.1 , pp. 53-59
    • Prakash, A.O.1    Tewari, R.K.2    Mathur, R.3
  • 34
    • 0027364413 scopus 로고
    • Mouse sperm-egg interaction in vitro in the presence of neem oil
    • Juneja SC, Williams RS Mouse sperm-egg interaction in vitro in the presence of neem oil. Life Sci 1993, 53(18):279-284.
    • (1993) Life Sci , vol.53 , Issue.18 , pp. 279-284
    • Juneja, S.C.1    Williams, R.S.2
  • 35
    • 0031924055 scopus 로고    scopus 로고
    • Immunocontraceptive activity guided fractionation and characterization of active constituents of neem (Azadirachta indica) seed extracts
    • Garg S, Talwar GP, Upadhyay SN Immunocontraceptive activity guided fractionation and characterization of active constituents of neem (Azadirachta indica) seed extracts. J Ethnopharmacol 1998, 60(3):235-246.
    • (1998) J Ethnopharmacol , vol.60 , Issue.3 , pp. 235-246
    • Garg, S.1    Talwar, G.P.2    Upadhyay, S.N.3
  • 38
    • 0001811701 scopus 로고
    • Effect of neem oil on blood sugar levels of normal, hyperglycaemic and diabetic animals
    • Sharma MK, Khare AK, Feroz H Effect of neem oil on blood sugar levels of normal, hyperglycaemic and diabetic animals. Indian Med Gaz 1983, 117:380-383.
    • (1983) Indian Med Gaz , vol.117 , pp. 380-383
    • Sharma, M.K.1    Khare, A.K.2    Feroz, H.3
  • 39
    • 0022967246 scopus 로고
    • Effect of neem seed oil on the blood glucose concentration of normal and alloxan diabetic rats
    • Dixit VP, Sinha R, Tank R Effect of neem seed oil on the blood glucose concentration of normal and alloxan diabetic rats. J Ethnopharmacol 1986, 17(1):95-98.
    • (1986) J Ethnopharmacol , vol.17 , Issue.1 , pp. 95-98
    • Dixit, V.P.1    Sinha, R.2    Tank, R.3
  • 40
    • 0019788728 scopus 로고
    • Anti-arthritic and anti-inflammatory actions of nimbidin
    • Pillai NR, Santhakumari G Anti-arthritic and anti-inflammatory actions of nimbidin. Planta Med 1981, 43:59-63.
    • (1981) Planta Med , vol.43 , pp. 59-63
    • Pillai, N.R.1    Santhakumari, G.2
  • 41
    • 84883796337 scopus 로고
    • Effect of neem oil and its constituents on cotton pellet inflammation
    • Shankaranarayan D Effect of neem oil and its constituents on cotton pellet inflammation. Mediscope 1978, 20:273-274.
    • (1978) Mediscope , vol.20 , pp. 273-274
    • Shankaranarayan, D.1
  • 42
    • 0033878929 scopus 로고    scopus 로고
    • Anti-microbial activity of a new vaginal contraceptive NIM-76 from neem oil (Azadirachta indica)
    • SaiRam M, Ilavazhagan G, Sharma SK, Dhanraj SA, Suresh B, Parida MM, et al. Anti-microbial activity of a new vaginal contraceptive NIM-76 from neem oil (Azadirachta indica). J Ethnopharmacol 2000, 71(3):377-382.
    • (2000) J Ethnopharmacol , vol.71 , Issue.3 , pp. 377-382
    • SaiRam, M.1    Ilavazhagan, G.2    Sharma, S.K.3    Dhanraj, S.A.4    Suresh, B.5    Parida, M.M.6
  • 44
    • 0024288013 scopus 로고
    • [Experimental study of the effect of raw materials of the neem tree and neem extracts on dermatophytes, yeasts and molds.]
    • German.
    • Khan M, Schneider B, Wassilew SW, Splanemann V [Experimental study of the effect of raw materials of the neem tree and neem extracts on dermatophytes, yeasts and molds.]. Z Hautkr 1988, 63(6):499-502. German.
    • (1988) Z Hautkr , vol.63 , Issue.6 , pp. 499-502
    • Khan, M.1    Schneider, B.2    Wassilew, S.W.3    Splanemann, V.4
  • 46
    • 0021257159 scopus 로고
    • Effects of nimbidin on acute and chronic gastroduodenal ulcer models in experimental animals
    • Pillai NR, Santhakumari G Effects of nimbidin on acute and chronic gastroduodenal ulcer models in experimental animals. Planta Med 1984, 50(2):143-146.
    • (1984) Planta Med , vol.50 , Issue.2 , pp. 143-146
    • Pillai, N.R.1    Santhakumari, G.2
  • 49
    • 33745957759 scopus 로고    scopus 로고
    • Cytotoxic and antiproliferative effects induced by a non terpenoid polar extract of A. indica seeds on 3T6 murine fibroblasts in culture
    • Di Ilio V, Pasquariello N, van der Esch AS, Cristofaro M, Scarsella G, Risuleo G Cytotoxic and antiproliferative effects induced by a non terpenoid polar extract of A. indica seeds on 3T6 murine fibroblasts in culture. Mol Cell Biochem 2006, 287(1-2):69-77.
    • (2006) Mol Cell Biochem , vol.287 , Issue.1-2 , pp. 69-77
    • Di Ilio, V.1    Pasquariello, N.2    van der Esch, A.S.3    Cristofaro, M.4    Scarsella, G.5    Risuleo, G.6
  • 50
    • 84871456372 scopus 로고    scopus 로고
    • Effects of reduced-risk pesticides and plant growth regulators on rove beetle (Coleoptera: Staphylinidae) adults
    • Echegaray ER, Cloyd RA Effects of reduced-risk pesticides and plant growth regulators on rove beetle (Coleoptera: Staphylinidae) adults. J Econ Entomol 2012, 105(6):2097-2106.
    • (2012) J Econ Entomol , vol.105 , Issue.6 , pp. 2097-2106
    • Echegaray, E.R.1    Cloyd, R.A.2
  • 51
    • 77955012283 scopus 로고    scopus 로고
    • Deleterious activity of natural products on postures of Spodoptera frugiperda (Lepidoptera: Noctuidae) and Diatraea saccharalis (Lepidoptera: Pyralidae)
    • Tavares WS, Cruz I, Fonseca FG, Gouveia NL, Serrão JE, Zanuncio JC Deleterious activity of natural products on postures of Spodoptera frugiperda (Lepidoptera: Noctuidae) and Diatraea saccharalis (Lepidoptera: Pyralidae). Z Naturforsch C 2010, 65(5-6):412-418.
    • (2010) Z Naturforsch C , vol.65 , Issue.5-6 , pp. 412-418
    • Tavares, W.S.1    Cruz, I.2    Fonseca, F.G.3    Gouveia, N.L.4    Serrão, J.E.5    Zanuncio, J.C.6
  • 53
    • 0022177313 scopus 로고
    • Neem leaf poisoning. Reply from the authors
    • Sivashanmugam R Neem leaf poisoning. Reply from the authors. J Assoc Physicians India 1985, 33:817.
    • (1985) J Assoc Physicians India , vol.33 , pp. 817
    • Sivashanmugam, R.1
  • 54
    • 0020034712 scopus 로고
    • Reye-like syndrome due to margosa oil poisoning: report of a case with postmortem findings
    • Sinniah D, Baskaran G, Looi LM, Leong KL Reye-like syndrome due to margosa oil poisoning: report of a case with postmortem findings. Am J Gastroenterol 1982, 77(3):158-161.
    • (1982) Am J Gastroenterol , vol.77 , Issue.3 , pp. 158-161
    • Sinniah, D.1    Baskaran, G.2    Looi, L.M.3    Leong, K.L.4
  • 56
    • 0025175066 scopus 로고
    • Margosa oil poisoning as a cause of toxic encephalopathy
    • Lai SM, Lim KW, Cheng HK Margosa oil poisoning as a cause of toxic encephalopathy. Singapore Med J 1990, 31(5):463-465.
    • (1990) Singapore Med J , vol.31 , Issue.5 , pp. 463-465
    • Lai, S.M.1    Lim, K.W.2    Cheng, H.K.3
  • 57
    • 0021091387 scopus 로고
    • Mutagenicity testing of two tropical plant materials with pesticidal potential in Salmonella typhimurium: Phytolacca dodecandra berries and oil from seeds of Azadirachta indica
    • Jongen WMF, Koeman JH Mutagenicity testing of two tropical plant materials with pesticidal potential in Salmonella typhimurium: Phytolacca dodecandra berries and oil from seeds of Azadirachta indica. Environ Mutagen 1983, 5(5):687-694.
    • (1983) Environ Mutagen , vol.5 , Issue.5 , pp. 687-694
    • Jongen, W.M.F.1    Koeman, J.H.2
  • 58
    • 0023472693 scopus 로고
    • Mutagenicity tests of cashewnut shell liquid, rice-bran oil and other vegetable oils using the Salmonella typhimurium/microsome system
    • Polasa K, Rukmini C Mutagenicity tests of cashewnut shell liquid, rice-bran oil and other vegetable oils using the Salmonella typhimurium/microsome system. Food Chem Toxicol 1987, 25(10):763-766.
    • (1987) Food Chem Toxicol , vol.25 , Issue.10 , pp. 763-766
    • Polasa, K.1    Rukmini, C.2


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