Basic concepts and principles of stoichiometric modeling of metabolic networks

Biotechnology Journal

Volumn 8, Issue 9, 2013, Pages 997-1008

  Maarleveld, Timo R ^a,b,c   Khandelwal, Ruchir A ^b   Olivier, Brett G ^b   Teusink, Bas ^b,d   Bruggeman, Frank J ^b,d  

^a CWI   (Netherlands)

^b AMSTERDAM INSTITUTE FOR MOLECULES   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d KLUYVER CENTRE FOR GENOMICS OF INDUSTRIAL FERMENTATION   (Netherlands)

Author keywords

Constraint based modeling; Flux balance analysis; Flux modes; Metabolism; Optimal solution space

Indexed keywords

CONSTRAINT-BASED MODELING; ENVIRONMENTAL CONDITIONS; FLUX BALANCE ANALYSIS; INDISPENSABLE TOOLS; MATHEMATICAL DEFINITIONS; METABOLIC NETWORK; OPTIMAL SOLUTIONS; STOICHIOMETRIC MODELS;

CHEMICAL ANALYSIS;

METABOLISM;

FLUX BALANCE ANALYSIS; FLUX VARIABILITY ANALYSIS; MATHEMATICAL MODEL; METABOLIC PARAMETERS; METABOLISM; METABOLITE; PRIORITY JOURNAL; REVIEW; STEADY STATE; STEADY STATE FLUX MODE; STOICHIOMETRY;

CONSTRAINT-BASED MODELING; FLUX BALANCE ANALYSIS; FLUX MODES; METABOLISM; OPTIMAL SOLUTION SPACE;

ALGORITHMS; CELLS; COMPUTER SIMULATION; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL;

EID: 84883809652     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201200291     Document Type: Review

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