Post-transplant outcomes of children bridged to transplant with the berlin heart EXCOR pediatric ventricular assist device

Circulation

Volumn 128, Issue SUPPL.1, 2013, Pages

  Eghtesady, Pirooz ^a   Almond, Christopher S D ^b   Tjossem, Christine ^c   Epstein, Deirdre ^a   Imamura, Michiaki ^d   Turrentine, Mark ^e   Tweddell, James ^f   Jaquiss, Robert D B ^g   Canter, Charles ^a  

^a ST LOUIS CHILDREN S HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c Berlin Heart Inc   (United States)

^d ARKANSAS CHILDREN S HOSPITAL   (United States)

^e RILEY HOSPITAL FOR CHILDREN   (United States)

^f Children's Hospital of Wisconsin ^*  (United States)

^g DUKE CHILDREN S HOSPITAL   (United States)

Author keywords

Heart failure; Heart assist device; Pediatrics; Surgery; Transplantation

Indexed keywords

ADOLESCENT; ARTICLE; CARDIOMYOPATHY; CONGENITAL HEART DISEASE; HEART GRAFT; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; PRIORITY JOURNAL; RISK FACTOR; SURVIVAL; TREATMENT OUTCOME; VENTRICULAR ASSIST DEVICE;

HEART FAILURE; HEART-ASSIST DEVICE; PEDIATRICS; SURGERY; TRANSPLANTATION;

ADOLESCENT; BERLIN; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; HEART TRANSPLANTATION; HEART-ASSIST DEVICES; HUMANS; MALE; POSTOPERATIVE CARE; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84883805851     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.000446     Document Type: Article

References (22)

1. FDA approval (h100004) of the Berlin heart EXCOR pediatric ventricular assist device. Available at http://www.fda.gov/NewsEvents/Newsroom/ PressAnnouncements/ucm283956.htm. Accessed August 4, 2013.
2. Fraser CD Jr, Jaquiss RD, Rosenthal DN, Humpl T, Canter CE, Blackstone EH, Naftel DC, Ichord RN, Bomgaars L, Tweddell JS, Massicotte MP, Turrentine MW, Cohen GA, Devaney EJ, Pearce FB, Carberry KE, Kroslowitz R, Almond CS; Berlin Heart Study Investigators. Prospective trial of a pediatric ventricular assist device. N Engl J Med. 2012;367:532-541.
3. Almond CS, Singh TP, Gauvreau K, Piercey GE, Fynn-Thompson F, Rycus PT, Bartlett RH, Thiagarajan RR. Extracorporeal membrane oxygenation for bridge to heart transplantation among children in the United States: Analysis of data from the Organ Procurement and Transplant Network and Extracorporeal Life Support Organization Registry. Circulation. 2011;123:2975-2984.
4. Morales DL, Zafar F, Rossano JW, Salazar JD, Jefferies JL, Graves DE, Heinle JS, Fraser CD Jr. Use of ventricular assist devices in children across the United States: Analysis of 7.5 million pediatric hospitalizations. Ann Thorac Surg. 2010;90:1313-1318; discussion 1318.
5. Almond CS, Buchholz H, Massicotte P, Ichord R, Rosenthal DN, Uzark K, Jaquiss RD, Kroslowitz R, Kepler MB, Lobbestael A, Bellinger D, Blume ED, Fraser CD Jr, Bartlett RH, Thiagarajan R, Jenkins K. Berlin Heart EXCOR Pediatric ventricular assist device Investigational Device Exemption study: Study design and rationale. Am Heart J. 2011;162:425-435.e6.
6. Schwartz GJ, Haycock GB, Edelmann CM Jr, Spitzer A. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics. 1976;58:259-263.
7. Alba AC, Rao V, Ivanov J, Ross HJ, Delgado DH. Usefulness of the INTERMACS scale to predict outcomes after mechanical assist device implantation. J Heart Lung Transplant. 2009;28:827-833.
8. Jaski BE, Kim JC, Naftel DC, Jarcho J, Costanzo MR, Eisen HJ, Kirklin JK, Bourge RC; Cardiac Transplant Research Database Research Group. Cardiac transplant outcome of patients supported on left ventricular assist device vs. intravenous inotropic therapy. J Heart Lung Transplant. 2001;20:449-456.
9. Almond CS, Morales DL, Blackstone EH, Turrentine MW, Imamura M, Massicotte MP, Jordan LC, Devaney EJ, Ravishankar C, Kanter KR, Holman W, Kroslowitz R, Tjossem C, Thuita L, Cohen GA, Buchholz H, St Louis JD, Nguyen K, Niebler RA, Walters HL 3rd, Reemtsen B, Wearden PD, Reinhartz O, Guleserian KJ, Mitchell MB, Bleiweis MS, Canter CE, Humpl T. Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children. Circulation. 2013;127:1702-1711.
10. Morales DL, Almond CS, Jaquiss RD, Rosenthal DN, Naftel DC, Massicotte MP, Humpl T, Turrentine MW, Tweddell JS, Cohen GA, Kroslowitz R, Devaney EJ, Canter CE, Fynn-Thompson F, Reinhartz O, Imamura M, Ghanayem NS, Buchholz H, Furness S, Mazor R, Gandhi SK, Fraser CD Jr. Bridging children of all sizes to cardiac transplantation: The initial multicenter North American experience with the Berlin Heart EXCOR ventricular assist device. J Heart Lung Transplant. 2011;30:1-8.
11. Karamlou T, Gelow J, Diggs BS, Tibayan FA, Mudd JM, Guyton SW, Slater MS, Song HK. Mechanical circulatory support pathways that maximize post-heart transplant survival. Ann Thorac Surg. 2013;95:480-485; discussion 485.
12. Patlolla V, Patten RD, Denofrio D, Konstam MA, Krishnamani R. The effect of ventricular assist devices on post-transplant mortality an analysis of the United network for organ sharing thoracic registry. J Am Coll Cardiol. 2009;53:264-271.
13. Bittner HB, Lehmann S, Rastan A, Garbade J, Binner C, Mohr FW, Barten MJ. Outcome of extracorporeal membrane oxygenation as a bridge to lung transplantation and graft recovery. Ann Thorac Surg. 2012;94:942-949; author reply 949.
14. Arnaoutakis GJ, George TJ, Kilic A, Weiss ES, Russell SD, Conte JV, Shah AS. Effect of sensitization in us heart transplant recipients bridged with a ventricular assist device: Update in a modern cohort. J Thorac Cardiovasc Surg. 2011;142:1236-1245, 1245 e1231.
15. DeNofrio D, Rho R, Morales FJ, Kamoun M, Kearns J, Dorozinsky C, Rosengard BR, Acker MA, Loh E. Detection of anti-HLA antibody by flow cytometry in patients with a left ventricular assist device is associated with early rejection following heart transplantation. Transplantation. 2000;69:814-818.
16. John R, Pagani FD, Naka Y, Boyle A, Conte JV, Russell SD, Klodell CT, Milano CA, Rogers J, Farrar DJ, Frazier OH. Post-cardiac transplant survival after support with a continuous-flow left ventricular assist device: Impact of duration of left ventricular assist device support and other variables. J Thorac Cardiovasc Surg. 2010;140:174-181.
17. Drakos SG, Kfoury AG, Kotter JR, Reid BB, Clayson SE, Selzman CH, Stehlik J, Fisher PW, Merida M 3rd, Eckels DD, Brunisholz K, Horne BD, Stoker S, Li DY, Renlund DG. Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of postimplantation human leukocyte antigen-allosensitization. J Heart Lung Transplant. 2009;28:838-842.
18. Kirsch L, Timmermans T, Van Caenegem O, Gurne O, Noirhomme P, Jacquet LM, Latinne D, Poncelet AJ. Allosensitization in bridge to transplant Novacor left ventricular assist device patients: Analysis of longterm outcomes with regard to acute rejection and chronic allograft vasculopathy. Eur J Cardiothorac Surg. 2008;34:268-274; discussion 274.
19. Malickaite R, Rucinskas K, Staneviciene A, Miniauskas S, Maneikiene V, Zuoziene G, Sirvydis V. Sensitisation and post-transplant course after the implantation of ventricular assist device. Interact Cardiovasc Thorac Surg. 2009;8:339-342; discussion 342.
20. Ameduri RK, Zheng J, Schechtman KB, Hoffman TM, Gajarski RJ, Chinnock R, Naftel DC, Kirklin JK, Dipchand AI, Canter CE. Has late rejection decreased in pediatric heart transplantation in the current erä. A multi-institutional study. J Heart Lung Transplant. 2012;31:980-986.
21. Engin C, Ayik F, Oguz E, Eygi B, Yagdi T, Karakula S, Ozbaran M. Ventricular assist device as a bridge to heart transplantation in adults. Transplant Proc. 2011;43:927-930.
22. Fan Y, Weng YG, Huebler M, Cowger J, Morales D, Franz N, Xiao YB, Potapov E, Hetzer R. Predictors of in-hospital mortality in children after long-term ventricular assist device insertion. J Am Coll Cardiol. 2011;58:1183-1190.