An increase in the clinical isolation of acquired AmpC β-Lactamase- producing klebsiella pneumoniae in Korea from 2007 to 2010

Annals of Laboratory Medicine

Volumn 33, Issue 5, 2013, Pages 353-355

  Park, Min Jeong ^a   Kim, Taek Kyung ^b   Song, Wonkeun ^a   Kim, Jae Seok ^a   Kim, Han Sung ^a   Lee, Jacob ^a  

^a Hallym University College of Medicine   (South Korea)

^b Kangnam Sacred Heart Hospital   (South Korea)

Author keywords

AmpC lactamases; CMY 2; DHA 1; Klebsiella pneumoniae

Indexed keywords

AMPC BETA LACTAMASES; AMPC BETA-LACTAMASES; ANTIINFECTIVE AGENT; BACTERIAL DNA; BACTERIAL PROTEIN; BETA LACTAMASE;

AMPC Β-LACTAMASES; ARTICLE; CMY-2; DHA-1; DRUG EFFECT; ENTEROBACTERIACEAE INFECTION; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIPLEX POLYMERASE CHAIN REACTION; PHYSIOLOGY; PROTEUS MIRABILIS; SOUTH KOREA; STATISTICS; UNIVERSITY HOSPITAL;

AMPC Β-LACTAMASES; CMY-2; DHA-1; KLEBSIELLA PNEUMONIAE;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; DNA, BACTERIAL; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; HOSPITALS, UNIVERSITY; HUMANS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MULTIPLEX POLYMERASE CHAIN REACTION; PROTEUS MIRABILIS; REPUBLIC OF KOREA;

EID: 84883796199     PISSN: 22343806     EISSN: 22343814     Source Type: Journal    
DOI: 10.3343/alm.2013.33.5.353     Document Type: Article

References (12)

1. Philippon A, Arlet G, Jacoby GA. Plasmid-determined AmpC -lactamases. Antimicrob Agents Chemother 2002;46:1-11.
2. Bauernfeind A, Chong Y, Schweighart S. Extended broad spectrum -lactamase in Klebsiella pneumoniae including resistance to cephamycins. Infection 1989;17:316-21.
3. Song W, Kim JS, Kim HS, Yong D, Jeong SH, Park MJ, et al. Increasing trend in the prevalence of plasmid-mediated AmpC -lactamases in Enterobacteriaceae lacking chromosomal ampC gene at a Korean university hospital from 2002 to 2004. Diagn Microbiol Infect Dis 2006;55:219-24.
4. Prez-Prez FJ and Hanson ND. Detection of plasmid-mediated AmpC -lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol 2002;40:2153-62.
5. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Nineteenth informational supplement, M100-S21. Wayne, PA: CLSI, 2011.
6. Song W, Jeong SH, Kim HS, Kim HS, Shin DH, Roh KH, et al. Use of boronic acid disk methods to detect the combined expression of plasmid-mediated AmpC -lactamases and extended-spectrum -lactamases in clinical isolates of Klebsiella spp., Salmonella spp., and Proteus mirabilis. Diagn Microbiol Infect Dis 2007;57:315-8.
7. Anderson KF, Lonsway DR, Rasheed JK, Biddle J, Jensen B, McDougal LK, et al. Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae. J Clin Microbiol 2007;45:2723-5.
8. Giske CG, Gezelius L, Samuelsen O, Warner M, Sundsfjord A, Woodford N. A sensitive and specific phenotypic assay for detection of metallo-lactamases and KPC in Klebsiella pneumoniae with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin. Clin Microbiol Infect 2011;17:552-6.
9. Kaczmarek FM, Dib-Hajj F, Shang W, Gootz TD. High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of blaACT-1 -lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin PhoE. Antimicrob Agents Chemother 2006;50:3396-406.
10. Song W, Kim JS, Kim MN, Kim EC, Park YJ, Yong D, et al. Occurrence and genotypic distributions of plasmid-mediated AmpC -lactamase-producing Escherichia coli and Klebsiella pneumoniae in Korea. Korean J Lab Med 2002;22:410-6.
11. Song W, Suh B, Choi JY, Jeong SH, Jeon EH, Lee YK, et al. In vivo selection of carbapenem-resistant Klebsiellae pneumonia by OmpK36 loss during meropenem treatment. Diagn Microbiol Infect Dis 2009;65:447-9.
12. Shin SY, Bae IK, Kim J, Jeong SH, Yong D, Kim JM, et al. Resistance to carbapenems in sequence type 11 Klebsiella pneumoniae is related to DHA-1 and loss of OmpK35 and/or OmpK36. J Med Microbiol 2012;61:239-45.