-
1
-
-
33847035824
-
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
-
Abdelmohsen K, Pullmann R Jr, Lal A, Kim HH, Galban S, Yang X, Blethrow JD, Walker M, Shubert J, Gillespie DA, Furneaux H, Gorospe M (2007) Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell. 25, 543-557.
-
(2007)
Mol Cell.
, vol.25
, pp. 543-557
-
-
Abdelmohsen, K.1
Pullmann Jr., R.2
Lal, A.3
Kim, H.H.4
Galban, S.5
Yang, X.6
Blethrow, J.D.7
Walker, M.8
Shubert, J.9
Gillespie, D.A.10
Furneaux, H.11
Gorospe, M.12
-
2
-
-
40149096226
-
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence
-
Abdelmohsen K, Kuwano Y, Kim HH, Gorospe M (2008) Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol. Chem. 389, 243-255.
-
(2008)
Biol. Chem.
, vol.389
, pp. 243-255
-
-
Abdelmohsen, K.1
Kuwano, Y.2
Kim, H.H.3
Gorospe, M.4
-
3
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM (2011) Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232-236.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
LeBrasseur, N.K.4
Childs, B.G.5
van de Sluis, B.6
Kirkland, J.L.7
van Deursen, J.M.8
-
4
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
5
-
-
77958517467
-
MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts
-
Bonifacio LN, Jarstfer MB (2010) MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts. PLoS One 5, e12519.
-
(2010)
PLoS One
, vol.5
-
-
Bonifacio, L.N.1
Jarstfer, M.B.2
-
6
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
-
Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120, 513-522.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
7
-
-
80054715378
-
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
-
Cesana M, Cacchiarelli D, Legnini I, Santini T, Sthandier O, Chinappi M, Tramontano A, Bozzoni I (2011) A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 147, 358-369.
-
(2011)
Cell
, vol.147
, pp. 358-369
-
-
Cesana, M.1
Cacchiarelli, D.2
Legnini, I.3
Santini, T.4
Sthandier, O.5
Chinappi, M.6
Tramontano, A.7
Bozzoni, I.8
-
8
-
-
74949127989
-
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo
-
Debacq-Chainiaux F, Erusalimsky JD, Campisi J, Toussaint O (2009) Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat. Protoc. 4, 1798-1806.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1798-1806
-
-
Debacq-Chainiaux, F.1
Erusalimsky, J.D.2
Campisi, J.3
Toussaint, O.4
-
10
-
-
33847129281
-
Relationship between mRNA stability and length: an old question with a new twist
-
Feng L, Niu DK (2007) Relationship between mRNA stability and length: an old question with a new twist. Biochem. Genet. 45, 131-137.
-
(2007)
Biochem. Genet.
, vol.45
, pp. 131-137
-
-
Feng, L.1
Niu, D.K.2
-
11
-
-
77952105389
-
Inflammatory networks during cellular senescence: causes and consequences
-
Freund A, Orjalo AV, Desprez PY, Campisi J (2010) Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med. 16, 238-246.
-
(2010)
Trends Mol Med.
, vol.16
, pp. 238-246
-
-
Freund, A.1
Orjalo, A.V.2
Desprez, P.Y.3
Campisi, J.4
-
12
-
-
79951495822
-
lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements
-
Gong C, Maquat LE (2011) lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements. Nature 470, 284-288.
-
(2011)
Nature
, vol.470
, pp. 284-288
-
-
Gong, C.1
Maquat, L.E.2
-
13
-
-
79956315291
-
MicroRegulators come of age in senescence
-
Gorospe M, Abdelmohsen K (2011) MicroRegulators come of age in senescence. Trends Genet. 27, 233-241.
-
(2011)
Trends Genet.
, vol.27
, pp. 233-241
-
-
Gorospe, M.1
Abdelmohsen, K.2
-
14
-
-
84864395101
-
Long non-coding RNAs and human disease
-
Harries LW (2012) Long non-coding RNAs and human disease. Biochem. Soc. Trans. 40, 902-906.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 902-906
-
-
Harries, L.W.1
-
15
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37, 614-636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
16
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, Desmet CJ, Aarden LA, Mooi WJ, Peeper DS (2008) Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133, 1019-1031.
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
17
-
-
78349257844
-
The essence of senescence
-
Kuilman T, Michaloglou C, Mooi WJ, Peeper DS (2010) The essence of senescence. Genes Dev. 24, 2463-2479.
-
(2010)
Genes Dev.
, vol.24
, pp. 2463-2479
-
-
Kuilman, T.1
Michaloglou, C.2
Mooi, W.J.3
Peeper, D.S.4
-
18
-
-
46849122501
-
p16(INK4a) translation suppressed by miR-24
-
Lal A, Kim HH, Abdelmohsen K, Kuwano Y, Pullmann R Jr, Srikantan S, Subrahmanyam R, Martindale JL, Yang X, Ahmed F, Navarro F, Dykxhoorn D, Lieberman J, Gorospe M (2008) p16(INK4a) translation suppressed by miR-24. PLoS One 3, e1864.
-
(2008)
PLoS One
, vol.3
-
-
Lal, A.1
Kim, H.H.2
Abdelmohsen, K.3
Kuwano, Y.4
Pullmann Jr., R.5
Srikantan, S.6
Subrahmanyam, R.7
Martindale, J.L.8
Yang, X.9
Ahmed, F.10
Navarro, F.11
Dykxhoorn, D.12
Lieberman, J.13
Gorospe, M.14
-
19
-
-
84871069553
-
Epigenetic regulation by long noncoding RNAs
-
Lee JT (2012) Epigenetic regulation by long noncoding RNAs. Science 338, 1435-1439.
-
(2012)
Science
, vol.338
, pp. 1435-1439
-
-
Lee, J.T.1
-
20
-
-
77950826971
-
Microglia in the aging brain: relevance to neurodegeneration
-
Luo XG, Ding JQ, Chen SD (2010) Microglia in the aging brain: relevance to neurodegeneration. Mol. Neurodegener. 5, 12.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 12
-
-
Luo, X.G.1
Ding, J.Q.2
Chen, S.D.3
-
21
-
-
69249228684
-
Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts
-
Maes OC, Sarojini H, Wang E (2009) Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts. J. Cell. Physiol. 221, 109-119.
-
(2009)
J. Cell. Physiol.
, vol.221
, pp. 109-119
-
-
Maes, O.C.1
Sarojini, H.2
Wang, E.3
-
22
-
-
77957566465
-
MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence
-
Marasa BS, Srikantan S, Martindale JL, Kim MM, Lee EK, Gorospe M, Abdelmohsen K (2010) MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence. Aging 2, 333-343.
-
(2010)
Aging
, vol.2
, pp. 333-343
-
-
Marasa, B.S.1
Srikantan, S.2
Martindale, J.L.3
Kim, M.M.4
Lee, E.K.5
Gorospe, M.6
Abdelmohsen, K.7
-
23
-
-
84861469589
-
Cellular senescence: a double-edged sword in the fight against cancer
-
Ohtani N, Takahashi A, Mann DJ, Hara E (2012) Cellular senescence: a double-edged sword in the fight against cancer. Exp. Dermatol. 21(Suppl 1), 1-4.
-
(2012)
Exp. Dermatol.
, vol.21
, Issue.SUPPL 1
, pp. 1-4
-
-
Ohtani, N.1
Takahashi, A.2
Mann, D.J.3
Hara, E.4
-
24
-
-
80051941094
-
Identification of novel transcripts in annotated genomes using RNA-Seq
-
Roberts A, Pimentel H, Trapnell C, Pachter L (2011a) Identification of novel transcripts in annotated genomes using RNA-Seq. Bioinformatics 27, 2325-2329.
-
(2011)
Bioinformatics
, vol.27
, pp. 2325-2329
-
-
Roberts, A.1
Pimentel, H.2
Trapnell, C.3
Pachter, L.4
-
25
-
-
79952709611
-
Improving RNA-Seq expression estimates by correcting for fragment bias
-
Roberts A, Trapnell C, Donaghey J, Rinn JL, Pachter L (2011b) Improving RNA-Seq expression estimates by correcting for fragment bias. Genome Biol. 12, R22.
-
(2011)
Genome Biol.
, vol.12
-
-
Roberts, A.1
Trapnell, C.2
Donaghey, J.3
Rinn, J.L.4
Pachter, L.5
-
26
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F, Campisi J (2011) Four faces of cellular senescence. J. Cell Biol. 192, 547-556.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
27
-
-
77955727216
-
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase
-
Sanduja S, Kaza V, Dixon DA (2009) The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase. Aging 1, 803-817.
-
(2009)
Aging
, vol.1
, pp. 803-817
-
-
Sanduja, S.1
Kaza, V.2
Dixon, D.A.3
-
28
-
-
84868705910
-
Long noncoding RNAs in cardiac development and pathophysiology
-
Schonrock N, Harvey RP, Mattick JS (2012) Long noncoding RNAs in cardiac development and pathophysiology. Circ. Res. 111, 1349-1362.
-
(2012)
Circ. Res.
, vol.111
, pp. 1349-1362
-
-
Schonrock, N.1
Harvey, R.P.2
Mattick, J.S.3
-
29
-
-
84872512759
-
NF90 coordinately represses the senescence-associated secretory phenotype
-
Tominaga-Yamanaka K, Abdelmohsen K, Martindale JL, Yang X, Taub DD, Gorospe M (2012) NF90 coordinately represses the senescence-associated secretory phenotype. Aging 4, 695-708.
-
(2012)
Aging
, vol.4
, pp. 695-708
-
-
Tominaga-Yamanaka, K.1
Abdelmohsen, K.2
Martindale, J.L.3
Yang, X.4
Taub, D.D.5
Gorospe, M.6
-
30
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, Salzberg SL, Wold BJ, Pachter L (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-515.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
Williams, B.A.2
Pertea, G.3
Mortazavi, A.4
Kwan, G.5
van Baren, M.J.6
Salzberg, S.L.7
Wold, B.J.8
Pachter, L.9
-
31
-
-
84876003231
-
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB
-
e1003368
-
Tripathi V, Shen Z, Chakraborty A, Giri S, Freier SM, Wu X, Zhang Y, Gorospe M, Prasanth SG, Lal A, Prasanth KV (2013) Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet. 9, e1003368.
-
(2013)
PLoS Genet.
, vol.9
-
-
Tripathi, V.1
Shen, Z.2
Chakraborty, A.3
Giri, S.4
Freier, S.M.5
Wu, X.6
Zhang, Y.7
Gorospe, M.8
Prasanth, S.G.9
Lal, A.10
Prasanth, K.V.11
-
32
-
-
0037011958
-
p53 mutant mice that display early ageing-associated phenotypes
-
Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA (2002) p53 mutant mice that display early ageing-associated phenotypes. Nature 415, 45-53.
-
(2002)
Nature
, vol.415
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Igelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
Park, S.H.11
Thompson, T.12
Karsenty, G.13
Bradley, A.14
Donehower, L.A.15
-
33
-
-
0034908634
-
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence
-
Wang W, Yang X, Cristofalo VJ, Holbrook NJ, Gorospe M (2001) Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence. Mol. Cell. Biol. 21, 5889-5898.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5889-5898
-
-
Wang, W.1
Yang, X.2
Cristofalo, V.J.3
Holbrook, N.J.4
Gorospe, M.5
-
34
-
-
80053609114
-
MicroRNA regulation of ionizing radiation-induced premature senescence
-
Wang Y, Scheiber MN, Neumann C, Calin GA, Zhou D (2011) MicroRNA regulation of ionizing radiation-induced premature senescence. Int. J. Radiat. Oncol. Biol. Phys. 81, 839-848.
-
(2011)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.81
, pp. 839-848
-
-
Wang, Y.1
Scheiber, M.N.2
Neumann, C.3
Calin, G.A.4
Zhou, D.5
-
35
-
-
79957840356
-
Long noncoding RNAs and human disease
-
Wapinski O, Chang HY (2011) Long noncoding RNAs and human disease. Trends Cell Biol. 21, 354-361.
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 354-361
-
-
Wapinski, O.1
Chang, H.Y.2
-
36
-
-
84867291885
-
Long noncoding RNA: its physiological and pathological roles
-
Yan B, Wang Z (2012) Long noncoding RNA: its physiological and pathological roles. DNA Cell Biol. 31(Suppl 1), S34-S41.
-
(2012)
DNA Cell Biol.
, vol.31
, Issue.SUPPL 1
-
-
Yan, B.1
Wang, Z.2
-
37
-
-
84883806117
-
Posttranscriptional gene regulation by long noncoding RNA
-
doi:10.1016/j.jmb.2012.11.024
-
Yoon JH, Abdelmohsen K, Gorospe M (2012) Posttranscriptional gene regulation by long noncoding RNA. J. Mol. Biol.. doi:10.1016/j.jmb.2012.11.024.
-
(2012)
J. Mol. Biol.
-
-
Yoon, J.H.1
Abdelmohsen, K.2
Gorospe, M.3
|