Application of a novel tool for diagnosing bile acid diarrhoea

Sensors (Switzerland)

Volumn 13, Issue 9, 2013, Pages 11899-11912

  Covington, James A ^a   Westenbrink, Eric W ^a   Ouaret, Nathalie ^a   Harbord, Ruth ^a   Bailey, Catherine ^b   O'Connell, Nicola ^b   Cullis, James ^b   Williams, Nigel ^b   Nwokolo, Chuka U ^b   Bardhan, Karna D ^a,c   Arasaradnam, Ramesh P ^a,b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY HOSPITALS COVENTRY AND WARWICKSHIRE NHS TRUST   (United Kingdom)

^c ROTHERHAM GENERAL HOSPITAL   (United Kingdom)

Author keywords

Bile acid diarrhea (bad); Bile acid malabsoprtion (bam); Electronic nose; Faims; Fermentome

Indexed keywords

DIAGNOSIS; DISEASES; GAS CHROMATOGRAPHY; ION MOBILITY SPECTROMETERS; MASS SPECTROMETRY; TOOLS; VOLATILE ORGANIC COMPOUNDS;

BILE ACID; ELECTRONIC NOSE; FAIMS; FERMENTOME; LINEAR DISCRIMINANT ANALYSIS; STATISTICAL DIFFERENCES; ULCERATIVE COLITIS; VOLATILE ORGANIC COMPOUND (VOC);

BODY FLUIDS;

EID: 84883792318     PISSN: 14248220     EISSN: None     Source Type: Journal    
DOI: 10.3390/s130911899     Document Type: Article

References (13)

1. Talley, N.J.; O'Keefe, E.A.; Zinsmeister, A.R.; Melton, L.J., 3rd. Prevalence of gastrointestinal symptoms in the elderly: A population-based study. Gastroenterology 1992, 102, 895-901.
2. Smith, M.; Cherian, P.; Raju, G.; Dawson, B.F.; Mahon, S.; Bardhan, K.D. Bile acid malabsorption in persistent diarrhoea. J. R. Coll. Physicians 2000, 34, 448-451.
3. Fauci, A.S.; Braunwald, E.; Isselbacher, K.J.; Wilson, J.D.; Martin, J.B.; Kasper, D.L.; Hauser, S.L.; Longo, D.L. The Practice of Medicine. Harrison's Principles of Internal Medicine, 14th ed.; McGraw-Hill: New York: NY, USA, 1998.
4. Walters, J.F.; Tasleem, A.M.; Omer, O.S.; Brydon, W.G.; Dew, T.; le Roux, C.W. A new mechanism for bile acid diarrhea: Defective feedback inhibition of bile acid biosynthesis. Clin. Gastroenterol. Hepatol. 2009, 7, 1189-1194.
5. Arasaradnam, R.P.; Pharaoh, M.W.; Williams, G.J.; Nwoloko, C.U.; Bardhan, K.D.; Kumar, S. Colonic fermentation-More than meets the nose. Med. Hypotheses 2009, 73, 753-756.
6. Arasaradnam, R.P.; Bardhan, K.D. Diet, Epigentics, and Colonic Fermentation and Their Role in Colorectal Cancer. In Bioactive Foods and Extracts-Cancer Treatment and Prevention, 1st ed.; Watson, R.R., Preedy, V.R., Eds.; Taylor Francis: New York, NY, USA, 2010; Chapter 27, pp. 427-440.
7. Gardner, J.W.; Craven, M.; Dow, C.; Hines, E.L. The prediction of bacteria type and culture growth phase by an electronic nose with a multi-layer perceptron network. Meas. Sci. Technol. 1998, 9, 120-127.
8. Covington, J.A.; Wedlake, L.; Andreyev, J.; Ouaret, N.; Thomas, M.G.; Nwokolo, C.U.; Bardhan, K.D.; Arasaradnam, R.P. The detection of patients at risk of gastrointestinal toxicity during pelvic radiotherapy by electronic nose and FAIMS: A pilot study. Sensors 2012, 12, 13002-13018.
9. Arasaradnam, R.P.; Ouaret, N.; Thomas, M.G.; Gold, P.; Quraishi, M.N.; Nwokolo, C.U.; Bardhan, K.D.; Covington, J.A. Evaluation of gut bacterial populations using an electronic e-nose and field asymmetric ion mobility spectrometry: Further i ig t i t 'ferme t mi ' Med. Eng. Technol. 2012, 36, 333-337.
10. Arasaradnam, R.P.; Quraishi, N.; Kyrou, I.; Nwoloko, C.U.; Joseph, M.; Kumar, S.; Bardhan, K.U.; Covington, J.A. Insights into 'fermentonomics': evalution of volatile organic compounds (VOCs) in himan disease using an electronic 'e-nose'. J. Med. Eng. Technol. 2011, 35, 87-91.
11. Wilson, A.D.; Baietto, M. Advances in electronic-nose technologies developed for biomedical applications. Sensors 2011, 11, 1105-1176.
12. Arasaradnam, R.P.; Ouaret, N.; Thomas, M.G.; Quraishi, N.; Heatherington, E.; Nwokolo, C.U.; Bardhan, K.D.; Covington, J.A. A novel tool for noninvasive diagnosis and tracking of patients with inflammatory bowel disease. Inflamm. Bowel Dis. 2013, 19, 999-1003.
13. Marchesi, J.R.; Holmes, E.; Khan, F.; Kochhar, S.; Scanlan, P.; Shanahan, F.; Wilson, I.D.; Wang, Y. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. J. Proteome Res. 2007, 6, 546-551.