Matrix metalloproteinase-9 deletion is associated with decreased mid-term vein wall fibrosis in experimental stasis DVT

Thrombosis Research

Volumn 132, Issue 3, 2013, Pages 360-366

  Deatrick, Kristopher B ^a   Obi, Andrea ^a   Luke, Catherine E ^a   Elfline, Megan A ^a   Sood, Vikram ^a   Upchurch, Gilbert R ^a   Jaffer, Farouc ^b   Wakefield, Thomas W ^a   Henke, Peter K ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Inflammation; Matrix metalloproteinases; Monocytes; Venous thrombosis

Indexed keywords

GELATINASE B; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROCOLLAGEN; PROCOLLAGEN 1; PROCOLLAGEN 3; TRANSFORMING GROWTH FACTOR BETA; TROPOELASTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN METABOLISM; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; ENZYME ACTIVITY; FIBROSIS; GENE DELETION; GENE EXPRESSION; INFERIOR CAVA VEIN; INFLAMMATION; LEUKOCYTE; MALE; MONOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VEIN WALL;

INFLAMMATION; MATRIX METALLOPROTEINASES; MONOCYTES; VENOUS THROMBOSIS;

ANIMALS; DISEASE MODELS, ANIMAL; FIBROSIS; GENE EXPRESSION; LEUKOCYTES, MONONUCLEAR; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; VEINS; VENOUS THROMBOSIS;

EID: 84883769919     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2013.06.027     Document Type: Article

References (38)

1. D. Lloyd-Jones, R.J. Adams, T.M. Brown, M. Carnethon, S. Dai, and G. De Simone Heart disease and stroke statistics - 2010 update. A report from the american heart association Circulation 121 2009 e92 e93
2. J.J. Bergan, G.W. Schmid-Schonbein, P.D. Smith, A.N. Nicolaides, M.R. Boisseau, and B. Eklof Chronic venous disease N Engl J Med 355 2006 488 498
3. B.F. Johnson, R.A. Manzo, R.O. Bergelin, and D.E. Strandness Jr. Relationship between changes in the deep venous system and the development of the postthrombotic syndrome after an acute episode of lower limb deep vein thrombosis: A one- to six-year follow-up J Vasc Surg 21 1995 307 312 [discussion 313]
4. P.K. Henke, and A.J. Comerota An update on etiology, prevention, and therapy of postthrombotic syndrome J Vasc Surg 53 2011 500 509
5. P.K. Henke, M.R. Varma, D.K. Moaveni, N.A. Dewyer, A.J. Moore, and E.M. Lynch Fibrotic injury after experimental deep vein thrombosis is determined by the mechanism of thrombogenesis Thromb Haemost 98 2007 1045 1055
6. K.B. Deatrick, J.L. Eliason, E.M. Lynch, A.J. Moore, N.A. Dewyer, and M.R. Varma Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model J Vasc Surg 42 2005 140 148
7. S. Dahi, J.G. Lee, D.H. Lovett, and R. Sarkar Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin J Vasc Surg 42 2005 539 545
8. P.K. Henke, M.R. Varma, K.B. Deatrick, N.A. Drewyer, E.M. Lynch, and A.J. Moore Neutrophils modulate post-thrombotic vein wall remodeling but not thrombus neovascularization Thromb Haemost 95 2006 272 281
9. N.A. Dewyer, V. Sood, E.M. Lynch, C.E. Luke, G.R. Upchurch Jr., and T.W. Wakefield Plasmin inhibition increases mmp-9 activity and decreases vein wall stiffness during venous thrombosis resolution J Surg Res 142 2007 357 363
10. V. Sood, C. Luke, E. Miller, M. Mitsuya, G.R. Upchurch Jr., and T.W. Wakefield Vein wall remodeling after deep vein thrombosis: Differential effects of low molecular weight heparin and doxycycline Ann Vasc Surg 24 2010 233 241
11. K.B. Deatrick, M. Elfline, N. Baker, C.E. Luke, S. Blackburn, C. Stabler, T.W. Wakefield, and P.K. Henke Postthrombotic vein wall remodeling: Preliminary observations J Vasc Surg 53 2011 139 146
12. P.K. Henke, A. Varga, S. De, C.B. Deatrick, J. Eliason, and D.A. Arenberg Deep vein thrombosis resolution is modulated by monocyte cxcr2-mediated activity in a mouse model Arterioscler Thromb Vasc Biol 24 2004 1130 1137
13. P.K. Henke, C.G. Pearce, D.M. Moaveni, A.J. Moore, E.M. Lynch, and C. Longo Targeted deletion of ccr2 impairs deep vein thombosis resolution in a mouse model J Immunol 177 2006 3388 3397
14. P.K. Henke, M. Mitsuya, C.E. Luke, M.A. Elfline, J.F. Baldwin, K.B. Deatrick, J.A. Diaz, V. Sood, G.R. Upchurch, T.W. Wakefield, C. Hogaboam, and S.L. Kunkel Toll-like receptor 9 signaling is critical for early experimental deep vein thrombosis resolution Arterioscler Thromb Vasc Biol 31 2011 43 49
15. V. Sood, C.E. Luke, K.B. Deatrick, J. Baldwin, E.M. Miller, and M. Elfline Urokinase plasminogen activator independent early experimental thrombus resolution: Mmp2 as an alternative mechanism Thromb Haemost 104 2010 1174 1183
16. L.C. Junqueira, G. Bignolas, and R.R. Brentani Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections Histochem J 11 1979 447 455
17. L. Cuttle, M. Nataatmadja, J.F. Fraser, M. Kempf, R.M. Kimble, and M.T. Hayes Collagen in the scarless fetal skin wound: Detection with picrosirius-polarization Wound Repair Regen 13 2005 198 204
18. D.D. Myers Jr., P.K. Henke, P.W. Bedard, S.K. Wrobleski, N. Kaila, and G. Shaw Treatment with an oral small molecule inhibitor of p selectin (psi-697) decreases vein wall injury in a rat stenosis model of venous thrombosis J Vasc Surg 44 2006 625 632
19. D.K. Moaveni, E.M. Lynch, C. Luke, V. Sood, G.R. Upchurch, and T.W. Wakefield Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin J Vasc Surg 47 2008 616 624
20. Z.S. Galis, and J.J. Khatri Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly Circ Res 90 2002 251 262
21. I. Singh, K.G. Burnand, M. Collins, A. Luttun, D. Collen, and B. Boelhouwer Failure of thrombus to resolve in urokinase-type plasminogen activator gene-knockout mice: Rescue by normal bone marrow-derived cells Circulation 107 2003 869 875
22. J.F. Baldwin, V. Sood, M.A. Elfline, C.E. Luke, N.A. Dewyer, and J.A. Diaz The role of urokinase plasminogen activator and plasmin activator inhibitor-1 on vein wall remodeling in experimental deep vein thrombosis J Vasc Surg 56 2012 1089 1097
23. W.C. Parks, C.L. Wilson, and Y.S. Lopez-Boado Matrix metalloproteinases as modulators of inflammation and innate immunity Nat Rev Immunol 4 2004 617 629
24. A. Cho, and M.A. Reidy Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injury Circ Res 91 2002 845 851
25. J. Zhang, L. Nie, M. Razavian, M. Ahmed, L.W. Dobrucki, and A. Asadi Molecular imaging of activated matrix metalloproteinases in vascular remodeling Circulation 118 2008 1953 1960
26. C.M. Ripplinger, C.W. Kessinger, C. Li, J.W. Kim, J.R. McCarthy, and R. Weissleder Inflammation modulates murine venous thrombosis resolution in vivo: Assessment by multimodal fluorescence molecular imaging Arterioscler Thromb Vasc Biol 32 2012 2616 2624
27. M.S. Pepper Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis Arterioscler Thromb Vasc Biol 21 2001 1104 1117
28. C. Johnson, and Z.S. Galis Matrix metalloproteinase-2 and -9 differentially regulate smooth muscle cell migration and cell-mediated collagen organization Arterioscler Thromb Vasc Biol 24 2004 54 60
29. M. Kuzuya, S. Kanda, T. Sasaki, N. Tamaya-Mori, X.W. Cheng, and T. Itoh Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia Circulation 108 2003 1375 1381
30. J.L. Johnson, A. Dwivedi, M. Somerville, S.J. George, and A.C. Newby Matrix metalloproteinase (mmp)-3 activates mmp-9 mediated vascular smooth muscle cell migration and neointima formation in mice Arterioscler Thromb Vasc Biol 31 2011 e35 e44
31. X. Yan, and Y.G. Chen Smad7: Not only a regulator, but also a cross-talk mediator of tgf-beta signalling Biochem J 434 2011 1 10
32. A.K. Ghosh, and D.E. Vaughan Pai-1 in tissue fibrosis J Cell Physiol 227 2012 493 507
33. B. Vaillant, M.G. Chiaramonte, A.W. Cheever, P.D. Soloway, and T.A. Wynn Regulation of hepatic fibrosis and extracellular matrix genes by the th response: New insight into the role of tissue inhibitors of matrix metalloproteinases J Immunol 167 2001 7017 7026
34. T.A. Wynn, and L. Barron Macrophages: Master regulators of inflammation and fibrosis Semin Liver Dis 30 2010 245 257
35. M. Nosaka, Y. Ishida, A. Kimura, and T. Kondo Immunohistochemical detection of mmp-2 and mmp-9 in a stasis-induced deep vein thrombosis model and its application to thrombus age estimation Int J Legal Med 124 2010 439 444
36. A.S. Antonov, G.N. Antonova, M. Fujii, P. ten Dijke, V. Handa, and J.D. Catravas Regulation of endothelial barrier function by tgf-beta type i receptor alk5: Potential role of contractile mechanisms and heat shock protein 90 J Cell Physiol 227 2012 759 771
37. K.T. Preissner, and U. Reuning Vitronectin in vascular context: Facets of a multitalented matricellular protein Semin Thromb Hemost 37 2011 408 424
38. R. Visse, and H. Nagase Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry Circ Res 92 2003 827 839