Analysis of manganese superoxide dismutase (MnSOD: Ala-9Val) and glutathione peroxidase (GSH-Px: Pro 197 Leu) gene polymorphisms in mood disorders

Bosnian Journal of Basic Medical Sciences

Volumn 13, Issue 2, 2013, Pages 109-113

  Cumurcu, Birgül Elbozan ^a   Ozyurt, Huseyin ^b   Ates, Omer ^b   Gul, Isil Gogcegoz ^c   Demir, Suleyman ^d   Karlidag, Rifat ^a  

^a INONU UNIVERSITY   (Turkey)

^b GAZIOSMANPASA UNIVERSITY   (Turkey)

^c Siverek State Hospital   (Turkey)

^d Diyarbakir Training and Research Hospital ^*  (Turkey)

Author keywords

Bipolar I disorder; Glutathione peroxidase; Major depressive disorder; Manganese superoxide dismutase; Polymorphism

Indexed keywords

EID: 84883764072     PISSN: 15128601     EISSN: 18404812     Source Type: Journal    
DOI: 10.17305/bjbms.2013.2390     Document Type: Article

References (19)

1. Serafini M, Del Rio D. Understanding the association between dietary antioxidants, redox status and disease: is the total antioxidant capacity the right tool? Redox Rep 2004;9(3):145-152.
2. Herken H, Uz E, Ozyurt H, Virit O, Akyol O. Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation are increased in diff erent forms of schizophrenia. Mol Psychiatry 2001;6(1):66-73.
3. Lei XG, Cheng WH, McClung JP. Metabolic regulation and function of glutathione peroxidase-i. Annu Rev Nutr 2007;27:41-61.
4. Hori H, Ohmori O, Shinkai T, Kojima H, Okano C, Suzuki T., et al. Manganese superoxide dismutase gene polymorphism and schizophrenia: relation to tardive dyskinesia. Neuropsychopharmacology. 2000; 23(2):].70-177.
5. Fagiolini A. Medical monitoring in patients bipolar disorders: a review of data. J Clin Psychiatry 2008; 69 (6):16-18.
6. Kuloglu M, Ustundag B, Atmaca M, Canatan H, Tezcan AE, Bosn J Basic Med Sci 2013; 13 (2): 112-113
7. Cinkilinc N. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct 2002;2o(2):171-175.
8. Kunz M, Gama CS, Andreazza AC, Salvador M, Ceresér KM, Gomes FA., et al. Elevated serum superoxide dismutase and thio-barbituric acid reactive substances in diff erent phases of bipolar disorder and in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2008; 32(7):].677-1681.
9. Machado-Vieira R, Andreazza AC, Viale CI, Zanatto V, Cereser V Jr, da Silva Vargas R, et al. Oxidative stress parameters in un-medicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects. Neurosci Lett 2007;421(1):33-36.
10. Ozcan ME, Gulec M, Ozerol E, Polat R, Akyol O. Antioxidant enzyme activities and oxidative stress in aff ective disorders. Int Clin Psychopharmacol 2004;19(2):89-95.
11. Kotan VO, Sarandol E, Kirhan E, Ozkaya G, Kirli S. effects of long-term antidepressant treatment on oxidative status in major depressive disorder: a 24-week follow-up study. Prog Neuropsychopharmacol Biol Psychiatry 2011;3:1284-1290.
12. Cumurcu BE, Ozyurt H, Etikan I, Demir S, Karlidag R. Total antioxidant capacity and total oxidant status in patients with major depression: impact of antidepressant treatment. Psychiatry Clin Neurosci 2009; 63:639-645.
13. Pae CU, Yoon SJ, Patkar A, Kim JJ, Jun TY, Lee C, Paik IH. Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism and mood disorders: A preliminary study. Prog Neuropsychopharmacol Biol Psychiatry 2006; 3o(7):326-329.
14. Galecki P, Smigielski J, Florkowski A, Bobinska K, Pietras T, Szem-raj J. Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-s8T r and Ala-9Val) in patients with recurrent depressive disorder. Psychiatry Res 2010; 179(1):43-46.
15. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th edition. Washington DC: APA; 1994.
16. First MB, Spitzer RL, Gibbon M, Williams JBW, Gibbon M. Structured clinical interview of DSM-IV disorders-clinician version (SCID-CV). Washington, DC: APA; 1997.
17. Shinkai T, De Luca V, Zai G, Shaikh S, Matsumoto C, Arnold PD, et al. No association between the Proi97Leu polymorphism in the glutathione peroxidase (GPXi) gene and schizophrenia. Psychiatr Genet 2004;i4(3):177-i8o.
18. Al Hadithy AF, Ivanova SA, Pechlivanoglou P, Wilffert B, Semke A, Fedorenko O, et al. Missense polymorphisms in three oxidative-stress enzymes (GSTPi, SOD2, and GPXi) and dyskinesias in Russian psychiatric inpatients from Siberia. Hum Psychopharmacol 2010; 25(1):84-91.
19. Shinkai T, Müller DJ, De Luca V, Shaikh S, Matsumoto C, Hwang R., et al. Genetic association analysis of the glutathione peroxidase (GPXi) gene polymorphism (Proi97Leu) with tardive dyskinesia Psychiatry Res. 2006;141 (2):123-128.