Functional Analysis in Mouse Embryonic Stem Cells Reveals Wild-Type Activity for Three Msh6 Variants Found in Suspected Lynch Syndrome Patients

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Wielders, Eva A L ^a   Houlleberghs, Hellen ^a   Isik, Gözde ^a   te Riele, Hein ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; PROTEIN MSH6;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; EMBRYO; EMBRYONIC STEM CELL; GENE TARGETING; GENETIC VARIABILITY; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; MISMATCH REPAIR; MISSENSE MUTATION; MOUSE; MSH6 GENE; NONHUMAN; PROTEIN BLOOD LEVEL;

ALLELES; ANIMALS; CODON; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; HETEROZYGOTE; HUMANS; MICE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MUTATION, MISSENSE; MUTS HOMOLOG 2 PROTEIN; PHENOTYPE; RECOMBINATION, GENETIC;

EID: 84883754132     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074766     Document Type: Article

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